|1.||Scheinberg, Phillip: 16 articles (09/2015 - 07/2006)|
|2.||Young, Neal S: 16 articles (05/2015 - 08/2002)|
|3.||Kröger, Nicolaus: 14 articles (06/2010 - 12/2002)|
|4.||Kojima, Seiji: 11 articles (11/2015 - 04/2003)|
|5.||Bacigalupo, Andrea: 11 articles (10/2014 - 09/2002)|
|6.||Ayuk, Francis: 9 articles (05/2009 - 12/2002)|
|7.||Blaise, Didier: 8 articles (05/2015 - 07/2003)|
|8.||Russell, James A: 8 articles (08/2014 - 03/2007)|
|9.||Wu, Colin O: 8 articles (06/2014 - 12/2008)|
|10.||Zabelina, Tatjana: 8 articles (09/2008 - 12/2002)|
|1.||Aplastic Anemia (Anemia, Hypoplastic)
08/01/1987 - "Antithymocyte globulin (ATG), a horse antihuman thymus antiserum highly effective in the majority of patients with aplastic anemia, was studied for its in vitro effects on hematopoietic progenitor cells. "
12/01/1989 - "In contrast, two kinds of antilymphocyte globulin (ALG) were effective for 9.4% and 15.6% of the severe form of aplastic anemia, and two kinds of antithymocytoglobulin (ATG) were effective in 30.8% and 37.2% of the patients, although the difference between ALG and ATG was not statistically significant. "
09/01/2010 - "The aim of this study was to compare hematological response and overall survival in patients submitted to horse or rabbit antithymocyte globulin as first-line treatment for severe aplastic anemia. "
05/15/1991 - "Therapy with antilymphocyte globulin (ALG) has been shown to be effective in restoring hematopoiesis to some patients with aplastic anemia. "
01/20/1983 - "These data indicate that antithymocyte globulin is effective in improving hematopoiesis in some patients with aplastic anemia."
|2.||Graft vs Host Disease (Graft-Versus-Host Disease)
09/01/2008 - "Inclusion of antithymocyte globulin led to a better day 100 overall response rate (93% vs. 78%, p=0.03) and complete response rate (59% vs. 39%, p=0.04), to a lower incidence of both acute grade III/IV graft-versus-host-disease (11% vs. 22%, p=0.10) and chronic graft-versus-host disease (23% vs. 65%, p<0.001) and to a trend to improved event-free survival at 3 years (39% vs. 27%, p=0.5). "
09/01/2002 - "The efficacy of antithymocyte globulin (ATG) in the treatment of graft-versus-host disease (GvHD) is controversial. "
01/01/2015 - "Recent studies showing the addition of antithymocyte globulin (ATG) to the conditioning regimen improves engraftment and reduces the risk of graft-versus-host disease (GVHD).There are currently two ATG preparations in the USA, equine (or horse) and rabbit ATG. "
08/01/2007 - "The objective of study was to investigate the effect of low-dose antithymocyte globulin (ATG) on steroid-resistant severe acute graft versus host disease (aGVHD). "
11/01/2005 - "Results from few randomized trials show that antithymocyte globulin reduces acute and chronic graft-versus-host disease, and this is in keeping with results from retrospective analysis on large number of patients. "
05/01/1990 - "Time-related rates of infection by etiologic agents have shown a significant reduction in early bacterial, viral, and nocardial infections between groups I and III. With rabbit antithymocyte globulin 200 mg intramuscularly every day for 3 days, our current protocol, T-cells are significantly reduced and local and systemic toxicity is almost unnoticeable. "
04/26/1990 - "We conclude that 33B3.1 is as effective as antithymocyte globulin in the prevention of renal-transplant rejection, and its use results in fewer infections and side effects."
04/01/1983 - "This study suggests that infection with DHF induces predominately cold-reactive antilymphocyte antibodies in DHF patients that could potentially interact with peripheral blood cells of patients and modulate the humoral immune responses of patients during infection."
12/01/1980 - "Studies involving immune spleen cell transfer and treatment with antilymphocyte serum demonstrated the importance of cell-mediated immunity in HSV-2 infection. "
10/01/2015 - "In vivo T-cell depletion with anti-thymocyte globulin (ATG) can attenuate GvHD but may increase infection and relapse risks. "
|4.||Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/01/1996 - "In acquired aplastic anaemia, a high incidence of myelodysplastic syndrome (MDS) was noted in patients with aplastic anaemia, seemingly cured of their aplasia by antilymphocyte globulins (ALG). "
11/01/2003 - "The purpose of this study was to determine the efficacy of and tolerance to antithymocyte globulin (ATG)-based therapy in patients with myelodysplastic syndrome (MDS). "
05/01/1993 - "They responded well to antilymphocyte globulin (ALG) and presently have no evidence of a clonal disorder such as myelodysplastic syndrome (MDS) or paroxysmal nocturnal haemoglobinuria (PNH). "
07/01/2014 - "A phase II multicenter rabbit anti-thymocyte globulin trial in patients with myelodysplastic syndromes identifying a novel model for response prediction."
03/01/2004 - "A prospective, randomised, phase II study of horse antithymocyte globulin vs rabbit antithymocyte globulin as immune-modulating therapy in patients with low-risk myelodysplastic syndromes."
04/01/2003 - "Induction of complete remission of hypoplastic leukemia with antithymocyte globulin."
01/01/2010 - "The study assessed the results of 92 allo-HCTs depending on the presence or absence of ATG in conditioning modes, the doses of Atgam (60 mg/kg or more), the presence or absence of acute leukemia (AL) in remission before HCT. "
04/01/2003 - "These findings suggest the efficacy of antithymocyte globulin in treating certain hypoplastic leukemias."
01/01/2013 - "Therefore, there were no effects of KIR ligand incompatibility in the GVH direction on single CBT outcomes for acute leukemia patients without anti-thymocyte globulin use. "
10/01/2012 - "The possibility of antileukemic activity of antithymocyte globulin (ATG) was investigated in 8 human leukemic cell lines and primary leukemic cells from 15 leukemia patients. "
|9.||Granulocyte Colony-Stimulating Factor (G-CSF)
|10.||Antilymphocyte Serum (Anti-Thymocyte Globulin)
|2.||Transplantation (Transplant Recipients)
|3.||Stem Cell Transplantation
|4.||Homologous Transplantation (Allograft)
|5.||Bone Marrow Transplantation (Transplantation, Bone Marrow)