Local Anti-Infective Agents (Antiseptics)

Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.

Also Known As:

Antiseptics; Anti-Infective Agents, Local; Antiinfective Agents, Local; Antiinfective Agents, Topical; Local Antiinfective Agents; Topical Anti-Infective Agents; Topical Antiinfective Agents; Agents, Local Anti-Infective; Agents, Local Antiinfective; Agents, Topical Anti-Infective; Agents, Topical Antiinfective; Anti Infective Agents, Local; Anti Infective Agents, Topical; Local Anti Infective Agents; Local Microbicides; Topical Anti Infective Agents; Topical Microbicides; Anti-Infective Agents, Topical; Antiseptic; Microbicides, Local; Microbicides, Topical

Networked: 3032 relevant articles (247 outcomes, 354 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Therapeutic Uses: 47080
    - Anti-Infective Agents: 8032
      - Local Anti-Infective Agents: 3032
        Hand Sanitizers: 320

Experts

1.	Kramer, A: 22 articles (03/2017 - 01/2002)
2.	Kramer, Axel: 19 articles (01/2022 - 01/2005)
3.	Assadian, Ojan: 17 articles (04/2019 - 03/2004)
4.	Assadian, O: 12 articles (07/2017 - 12/2006)
5.	Schwarz, Frank: 9 articles (11/2021 - 02/2005)
6.	Dumville, Jo C: 9 articles (01/2018 - 03/2013)
7.	Junka, Adam: 8 articles (01/2022 - 12/2014)
8.	Bartoszewicz, Marzenna: 8 articles (10/2021 - 12/2014)
9.	Dissemond, Joachim: 8 articles (10/2021 - 12/2010)
10.	Bae, Jong-Sup: 8 articles (06/2021 - 08/2015)

Related Diseases

1.	Infections 09/01/2018 - "22 patients (2.2%) developed a post-biopsy infection with a significant reduction in the group receiving topical rectal antiseptic (0.8 vs. 3.3%, p = 0.01). " 07/01/2018 - "Methods We used either CH or 10% PI as skin antiseptics before CVC insertion, and assessed which agent was more protective against CVC-related infection. " 01/01/2018 - "Enumerating the steps involved in surgical infection prevention using a process mapping technique helped identify opportunities for improving adherence and plotting contextually relevant solutions, resulting in superior compliance with antiseptic standards. " 10/01/2018 - "There was a clear trend in all studies suggesting that intraoperative topical antiseptics are effective in preventing periprosthetic infection. " 03/01/2016 - "Recent researches have shown that the application of antiseptics is effective in the prevention of infection and is a support to targeted treatment. "
2.	Wounds and Injuries (Trauma) 08/01/2016 - "The discovery and establishment of safe and effective alternative antiseptics are important issues for the treatment of infected wounds. " 03/01/1984 - "An antiseptic barrier incorporated into the drainage system reduced the incidence of positive bile cultures during the drainage period although this did not afford a significant reduction in bacteremic episodes and positive wound cultures. " 10/01/2015 - "After participating in this educational activity, the participant should be better able to:1. Summarize causes and treatments for moisture balance issues of chronic wounds.2. Recognize the properties of dressings used for treatment for moisture management of chronic wounds and antiseptic agent cytotoxicity.3. Explain study findings of the effectiveness of dressing choices for treatment of chronic wounds. " 10/01/2014 - "To perceive them more clearly, the potential problems or complications in the management of chronic wounds can be classified into the following groups: problems mostly related to the use of wound coverage and other etiology related specificities of wound treatment; problems related to incompatibility of the agents used in wound treatment; and problems arising from failure to ensure aseptic and antiseptic performance conditions." 11/09/2022 - "The Impact of Antiseptic-Loaded Bacterial Nanocellulose on Different Biofilms-An Effective Treatment for Chronic Wounds?"
3.	Sepsis (Septicemia) 08/01/2018 - "Corrigendum to 'Antiseptic barrier cap effective in reducing central line-associated bloodstream infections: A systematic review and meta-analysis' [Int J Nurs Stud. " 04/01/2017 - "Antiseptic barrier cap effective in reducing central line-associated bloodstream infections: A systematic review and meta-analysis." 01/01/2023 - "Antiseptic bathing did not reduce central-line (CL) associated bloodstream infection (CLABSI) rates in intensive care units (ICU) according to a recent cluster randomised controlled trial (cRCT). " 07/01/2016 - "Antiseptic effect of sea cucumber (Holothuria atra) against multi-organ failure induced by sepsis: Molecular and histopathological study." 01/01/2023 - "Mixed efficacy was found for the topical application of antiseptics before transrectal biopsy to decrease postprocedural sepsis. "
4.	Surgical Wound Infection 11/16/2023 - "No study has evaluated the efficacy of using preoperative antiseptic dressings in reducing the rate of surgical site infection (SSI) in spine surgery thus far. " 07/01/2009 - "To study the efficacy of the reduction of bacterial colonization and surgical wound infection among these antiseptic. " 07/01/2023 - "The Efficacy of Antiseptic Treatment of Surgical Drains on Bacterial Colonisation and Surgical Site Infection Post Breast Surgery: A Systematic Review and Meta-Analysis." 10/01/2022 - "Efficacy of different preoperative skin antiseptics on the incidence of surgical site infections: a systematic review, GRADE assessment, and network meta-analysis." 11/01/2023 - "Antiseptic Skin Agents to Prevent Surgical Site Infection After Clean Implant Surgery: Subgroup Analysis of the NEWSkin Prep Trial."
5.	Gingivitis 01/01/2014 - "Conventional Analysis of Covariance (ANCOVA) on whole mouth mean plaque and gingivitis scores were originally conducted to demonstrate efficacy of adjunctive use of Cool Mint® LISTERINE® Antiseptic (EO) compared to negative control [brushing (B) or brushing/flossing (BF)] in each of 5 studies containing a 4 week evaluation. " 01/01/2013 - "This study also confirmed that an antiseptic EO rinse can provide a clinically significant benefit in reducing existing plaque and gingivitis." 06/01/2010 - "Studies indicate that effective antiseptic mouth-washes can provide significant gingivitis reduction beyond what can be accomplished with only brushing and flossing. " 09/01/1972 - "A study of the effects of antiseptic agents and a pulsating irrigating device on plaque and gingivitis." 07/11/2014 - "The purpose of this review was to perform a systematic search in the literature on antiseptics used to control supragingival biofilm and gingivitis in orthodontic patients. "

Related Drugs and Biologics

1.	Povidone-Iodine (Betadine)
2.	Anti-Bacterial Agents (Antibiotics)
3.	Chlorhexidine
4.	Solutions
5.	octenidine
6.	polihexanide
7.	chlorhexidine gluconate (Dyna-Hex)
8.	Local Anti-Infective Agents (Antiseptics)
9.	Silver
10.	Mouthwashes

Related Therapies and Procedures

1.	Catheters
2.	Therapeutics
3.	Central Venous Catheters
4.	Debridement
5.	Sutures (Suture)