An acute infection caused by the spore-forming bacteria BACILLUS ANTHRACIS. It commonly affects hoofed animals such as sheep and goats. Infection in humans often involves the skin (cutaneous anthrax), the lungs (inhalation anthrax), or the gastrointestinal tract. Anthrax is not contagious and can be treated with antibiotics.
Networked: 1592 relevant articles (140 outcomes, 146 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infection
2. Plague (Bubonic Plague)
3. Tularemia
4. Inflammation
5. Human Influenza (Influenza)


1. Leppla, Stephen H: 74 articles (11/2015 - 02/2002)
2. Moayeri, Mahtab: 40 articles (10/2015 - 02/2002)
3. Quinn, Conrad P: 27 articles (11/2015 - 10/2002)
4. Liu, Shihui: 24 articles (10/2015 - 02/2002)
5. Tang, Wei-Jen: 20 articles (07/2015 - 01/2002)
6. Bhatnagar, Rakesh: 19 articles (12/2015 - 04/2002)
7. Schneewind, Olaf: 17 articles (12/2015 - 07/2005)
8. Frankel, Arthur E: 17 articles (10/2015 - 02/2002)
9. Beyer, Wolfgang: 15 articles (07/2015 - 07/2003)
10. Duesbery, Nicholas S: 15 articles (01/2013 - 03/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Anthrax:
1. AntigensIBA
2. anthrax toxin (anthrax lethal factor)IBA
3. AntibodiesIBA
4. VaccinesIBA
5. Anti-Bacterial Agents (Antibiotics)IBA
6. Cutaneous anthraxIBA
7. Ciprofloxacin (Cipro)FDA LinkGeneric
8. Anthrax VaccinesIBA
9. DNA (Deoxyribonucleic Acid)IBA
10. Neutralizing AntibodiesIBA

Therapies and Procedures

1. Injections
2. Intramuscular Injections
02/12/2014 - "Effect of reduced dose schedules and intramuscular injection of anthrax vaccine adsorbed on immunological response and safety profile: a randomized trial."
10/01/2006 - "This MAb was effective in prophylactic and postsymptomatic treatment of rabbits exposed to aerosolized anthrax spores, and a single intramuscular injection of 1 mg/kg of body weight fully protected cynomolgus monkeys challenged with aerosolized anthrax spores. "
11/01/2012 - "A three-dose intramuscular injection schedule of anthrax vaccine adsorbed generates sustained humoral and cellular immune responses to protective antigen and provides long-term protection against inhalation anthrax in rhesus macaques."
09/01/2007 - "This recombinant Protective Antigen anthrax vaccine, when given with the adjuvant Alhydrogel to healthy adults in two intramuscular injections four weeks apart, is very well-tolerated and highly immunogenic."
01/01/2009 - "In addition, ChimeriVax-JE against yellow fever was administered to nonhuman primates by microneedles and generated protective levels of neutralizing antibodies that were more than seven times greater than those obtained with subcutaneous delivery; DNA plasmids encoding hepatitis B surface antigen were administered to mice and antibody and T cell responses at least as strong as hypodermic injections were generated; recombinant protective antigen of Bacillus anthracis was administered to rabbits and provided complete protection from lethal aerosol anthrax spore challenge at a lower dose than intramuscular injection; and DNA plasmids encoding four vaccinia virus genes administered to mice in combination with electroporation generated neutralizing antibodies that apparently included both Th1 and Th2 responses. "
3. Intranasal Administration
4. Therapeutics
5. Antibiotic Prophylaxis