Anthocyanins (Anthocyanin)

A group of FLAVONOIDS derived from FLAVONOLS, which lack the ketone oxygen at the 4-position. They are glycosylated versions of cyanidin, pelargonidin or delphinidin. The conjugated bonds result in blue, red, and purple colors in flowers of plants.

Also Known As:

Networked: 1720 relevant articles (175 outcomes, 428 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Ling, Wenhua: 30 articles (07/2022 - 08/2006)
2.	Shin, Sung Chul: 19 articles (11/2020 - 02/2006)
3.	Yang, Yan: 17 articles (07/2022 - 04/2011)
4.	Zheng, Xiaodong: 16 articles (06/2022 - 01/2013)
5.	Lee, Won Sup: 16 articles (03/2021 - 04/2009)
6.	Cassidy, Aedín: 15 articles (01/2022 - 12/2009)
7.	Xia, Min: 15 articles (04/2015 - 08/2006)
8.	Chen, Wei: 14 articles (12/2021 - 01/2013)
9.	Choi, Yung Hyun: 13 articles (03/2021 - 04/2009)
10.	Kim, Myeong Ok: 13 articles (01/2021 - 10/2013)

Related Diseases

1.	Inflammation (Inflammations) 06/22/2019 - "Results indicate that consumption of whole fruit high in anthocyanins can be beneficial for reducing inflammation and oxidative stress." 07/20/2021 - "Regarding anthocyanins' effects on inflammatory markers, there is a need for long-term clinical trials allowing for the quantifiable progression of inflammation. " 02/01/2020 - "This study indicated that berry anthocyanins reduced oxidative stress and inflammation via the inhibition of the NF-ƙB signaling pathway, which contributes to mitigating the diabetes-induced up-regulation of NF-ƙB." 01/01/2020 - "Impact of dietary anthocyanins on systemic and vascular inflammation: Systematic review and meta-analysis on randomised clinical trials." 05/27/2019 - "There is growing evidence from animal studies and human clinical trials that diets rich in anthocyanins, which are pigments in fruits and vegetables, protect against inflammation and increased gut permeability as well as improve colon health through their ability to alter bacterial metabolism and the microbial milieu within the intestines. "
2.	Neoplasms (Cancer) 01/01/2020 - "Pigmented food are an important part of the human diet, and anthocyanins have demonstrable protection against tumor production in mouse models and beneficial effects on human liver chemistry. " 01/01/2022 - "Anthocyanins are known for their therapeutic efficacy for many human diseases, including cancer. " 11/08/2023 - "Our study found a total anthocyanidin-rich diet was associated with a reduced risk of biliary cancer in Americans aged 55 to 74 years." 11/08/2023 - "This study provides evidence of an inverse association between total anthocyanidins intake and biliary cancer incidence. " 11/08/2023 - "This study used data from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial to investigate the relationship between total anthocyanidins intake and biliary cancer incidence. "
3.	Cardiovascular Diseases (Cardiovascular Disease) 07/10/2022 - "Many animal and in vitro experiments have also proven that anthocyanins have protective effects on cardiovascular-disease-related dysfunction. " 04/01/2012 - "Epidemiological studies have indicated a positive association between the intake of foods rich in anthocyanins and the protection against cardiovascular diseases. " 02/16/1998 - "Our results suggest that anthocyanins could be the key component in red wine in light of the protection against cardiovascular diseases, although this hypothesis needs in vivo evidence." 03/01/2023 - "Intervention trials and subsequent meta-analyses have suggested that anthocyanins could reduce the risks of cardiovascular diseases. " 12/01/2020 - "The Postprandial Effect of Anthocyanins on Cardiovascular Disease Risk Factors: a Systematic Literature Review of High-Fat Meal Challenge Studies."
4.	Obesity 03/01/2015 - "Here, we summarize the data on anthocyanin-mediated protection against obesity and T2DM and the underlying mechanisms. " 01/01/2023 - "Anthocyanin supplementation improves obesity-related inflammatory characteristics: A systematic review and meta-analysis of randomized controlled trials." 06/01/2022 - "The present study aimed to explore the beneficial effects of pomegranate peel anthocyanins (PPA) on obesity and gut microbiota in mice with high-fat diet (HFD)-induced obesity. " 06/21/2021 - "Effects of Anthocyanin Supplementation on Reduction of Obesity Criteria: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." 01/01/2021 - "Previous animal and in vitro studies indicated that anthocyanidins might contribute to the prevention of obesity, while epidemiological evidences were scarce and had not been conducted in children. "
5.	Insulin Resistance 10/01/2016 - "Mulberry anthocyanin extract ameliorates insulin resistance by regulating PI3K/AKT pathway in HepG2 cells and db/db mice." 01/01/2018 - "Studies conducted on humans and experimental animals showed that anthocyanins decrease insulin resistance. " 03/01/2017 - "The present study examined, at a molecular level, the effects of cyanidin-3-O-glucoside (C3G), a widely distributed anthocyanin, on PA-induced endothelial dysfunction and insulin resistance in human umbilical vein endothelial cells (HUVECs). " 11/20/2020 - "Once absorbed, anthocyanins positively modulate GLUT4 density and function in both skeletal muscle and adipose tissues via the upregulation of AMPK and restoration of insulin sensitivity. " 01/01/2020 - "We demonstrate the mechanism by which C3G, a major dietary anthocyanin, regulates energy metabolism and insulin sensitivity. "

Related Drugs and Biologics

1.	Anthocyanins (Anthocyanin)
2.	Antioxidants
3.	Polyphenols
4.	Flavonoids
5.	Glucose (Dextrose)
6.	Curcumin
7.	Resveratrol
8.	Biomarkers (Surrogate Marker)
9.	cyanidin
10.	Phytochemicals

Related Therapies and Procedures

1.	Oral Administration
2.	Chemoprevention
3.	Therapeutics
4.	Glycemic Control
5.	Radiotherapy