|2.||Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
|1.||Mumford, Sunni L: 16 articles (10/2015 - 10/2009)|
|2.||Schisterman, Enrique F: 16 articles (10/2015 - 10/2009)|
|3.||Wactawski-Wende, Jean: 16 articles (10/2015 - 10/2009)|
|4.||Perkins, Neil J: 13 articles (10/2015 - 10/2009)|
|5.||Schliep, Karen C: 10 articles (10/2015 - 03/2013)|
|6.||Sjaarda, Lindsey A: 6 articles (10/2015 - 06/2014)|
|7.||Laven, Joop S E: 6 articles (04/2015 - 11/2002)|
|8.||van Wely, Madelon: 6 articles (01/2014 - 01/2004)|
|9.||van der Veen, Fulco: 6 articles (01/2014 - 01/2004)|
|10.||Pollack, Anna Z: 6 articles (12/2013 - 08/2011)|
|1.||Clomiphene (Clomifene)FDA LinkGeneric
01/01/1990 - "Ovarian stimulation with pure urinary FSH (Fertinorm, Serono Freiburg, FRG) shows therapeutic efficacy in patients with chronic clomiphene-resistant anovulation and elevated androgen levels. "
05/01/1995 - "In conclusion, this study shows that the applied step-down regimen for gonadotrophin induction of ovulation can be a safe and effective treatment alternative for patients with clomiphene-resistant anovulation. "
01/01/2013 - "The M-OVIN study: does switching treatment to FSH and / or IUI lead to higher pregnancy rates in a subset of women with world health organization type II anovulation not conceiving after six ovulatory cycles with clomiphene citrate - a randomised controlled trial."
05/01/2011 - "Chinese herbal medicine and clomiphene citrate for anovulation: a meta-analysis of randomized controlled trials."
08/01/1996 - "Infertile female patients (n = 234) suffering from WHO group II anovulation, and who failed to became pregnant with clomiphene citrate, were included in a multicenter, prospective, clinical study of treatment with a protocol of chronic low-dose and small incremental rises with urinary purified or highly purified FSH. "
|2.||Metformin (Glucophage)FDA LinkGeneric
01/01/2003 - "Metformin is an effective treatment for anovulation in women with PCOS. "
09/01/2007 - "The aim of the study was to compare in a clinical setting the efficacy of CC and metformin as first-line approaches for treating anovulation in infertile PCOS patients. "
09/01/2013 - "These finding have implications for the use of metformin in the treatment of anovulation in women with PCOS."
04/01/2005 - "Does metformin modify ovarian responsiveness during exogenous FSH ovulation induction in normogonadotrophic anovulation? "
01/01/2003 - "Thus, similarly to obese PCOS women, nonobese PCOS subjects with anovulation may also benefit from metformin treatment."
03/01/1975 - "Gonadotropin therapy yielded good results in cases treated for anovulation (30% pregnancies) and for slight oligoasthenospermia (32.65% pregnancies). "
01/01/1983 - " Clinical trials with the formulation have shown it to be a safe and effective ultra-low dose combined OC agent whose mode of action is primarily gonadotropin suppression and subsequent anovulation."
08/01/1980 - "The purpose of this study was to determine which specific structures within the medial preoptic-anterior hypothalamic area are necessary to maintain cyclic ovulation in the rat, and to define the deifcit(s) in the feedback regulation of gonadotropin secretion associated with lesions that result in anovulation. "
01/01/1975 - "The study of longitudinal evolution of plasmatic gonadotropins in women receiving sulpirid, a psychotropic drug with a strong anti-ovulatory effect, shows the coexistence of anovulation and the peristance of a physiological pattern of gonadotropins during the first cycle of treatment. "
10/01/2012 - "Kisspeptin administration restored gonadotropin secretion and ovarian cyclicity, suggesting that kisspeptin neurons play a major role in hyperprolactinemic anovulation. "
|4.||Estrogens (Estrogen)FDA Link
10/01/1988 - "The present results indicate that development of PF and persistent anovulation are due to the direct action of estrogen (E) derived from T upon neonatal ovarian follicles and the neonatal hypothalamo-hypophysial system, and that T itself can induce ovary-independent vaginal changes, although 5 alpha-reduced androgen and estrogen derived from T seem to be more effective in this regard."
09/01/2013 - "Early onset of anovulation leading to prolonged estrogen exposure might be a risk factor for uterine carcinogenesis."
08/01/2013 - "A major factor for this increased malignancy risk is prolonged exposure of the endometrium to unopposed estrogen that results from anovulation. "
01/01/2007 - "Ovulation disorders: Part II. Anovulation associated with normal estrogen."
01/01/2007 - "Ovulation disorders: part I anovulation associated with estrogen deficiency."
|5.||Gonadotropin-Releasing Hormone (GnRH)FDA Link
11/01/1999 - "The low dose GnRH agonist treatment regimen induced anovulation in as much as 56% of patients, but these subjects were significantly older than those women who maintained ovulatory cycles throughout the study. "
01/01/1977 - "[Orientation studies on the management of anovulation using LH-releasing hormone]."
03/01/2014 - "Data illustrate that continuous administration of native GnRH is a highly efficient option for managing seasonal anovulation in mares and could be effectively used in the breeding industry if a user-friendly delivery option were available. "
01/01/2014 - "These data demonstrate that a selective loss of RP3V kisspeptin inputs to GnRH neurons during lactation is the likely mechanism causing lactational anovulation in the mouse. "
01/01/2014 - "Lactational anovulation in mice results from a selective loss of kisspeptin input to GnRH neurons."
04/01/1996 - "The "gold standard" for anovulation was weekly serum samples < or = 2 ng/ml progesterone. "
10/01/1992 - "To study the daily levels of salivary progesterone (P) during the menstrual cycles of adolescent girls 14 to 19 years of age and the occurrence of anovulations and defective luteal phases. "
10/01/2015 - "Serum progesterone was measured at 35 and 49 (±7) DIM (14 d apart); cows were considered to have prolonged anovulation if progesterone was <1ng/mL at both times. "
03/01/2015 - "High versus low daily stress was also associated with lower luteal progesterone (-10.4% [95% CI = -19.7% to -0.10%]) and higher odds of anovulation (adjusted odds ratio = 2.2 [95% CI = 1.0 to 4.7]). "
07/01/2014 - "Sporadic anovulation was identified using peak progesterone concentration. "
|7.||Follicle Stimulating Hormone (Follitropin)FDA Link
08/01/1997 - "In this current study we tested the efficacy of coculture with the buffalo rat liver cell line on pregnancy rates in women with a potentially poor prognosis for success with in vitro fertilization (previous in vitro fertilization failure, advanced maternal age, increased early follicular follicle-stimulating hormone levels, and anovulation). "
01/01/2004 - "Inadequate follicle-stimulating hormone is hypothesized to be a proximate cause of anovulation. "
12/01/1998 - "High frequency of luteal phase deficiency and anovulation in recreational women runners: blunted elevation in follicle-stimulating hormone observed during luteal-follicular transition."
03/01/1996 - "Our purpose was to determine whether decreased follicle stimulating hormone (FSH) activity, either systemic or at the follicular level, is involved in impaired follicle growth associated with normogonadotrophic anovulation. "
06/01/2012 - "It prevents folliculogenesis by reducing follicle sensitivity to follicle-stimulating hormone (FSH), and leads to anovulation when secreted in excess amounts in polycystic ovary syndrome (PCOS). "
06/01/2014 - "The objective of the study was to evaluate whether sporadic anovulation was associated with higher T and anti-müllerian hormone (AMH; marker of ovarian follicle count) concentrations in eumenorrheic women. "
06/01/1992 - "Although induction of ovulation with HMG in patients with anovulation is a complex procedure requiring strict clinical vigilance and advanced technological resources, in this clinical study it was possible to obtain similar results to other series, using high resolution ultrasound only, without daily measurements of hormones."
06/04/1971 - "[Comparative hormone-analyzing studies on corpus luteum insufficiency and anovulation during puberty and premenopause]."
10/01/2015 - "We assessed the relation between acute alcohol consumption, reproductive hormones, and markers of menstrual cycle dysfunction including sporadic anovulation, irregular cycle length, luteal phase deficiency, long menses, and heavy blood loss. "
07/01/2015 - "Few associations were found between analgesic medication use and reproductive hormones, but use during the follicular phase was associated with decreased odds of sporadic anovulation after adjusting for potential confounders. "
|9.||Insulin (Novolin)FDA Link
01/01/2006 - "Insulin is implicated in the mechanism of both anovulation and deficient oocyte development. "
08/01/2000 - "Hence, patients with HH have impaired insulin sensitivity to a degree similar to that seen in PCOS, suggesting a direct effect of anovulation on insulin sensitivity."
04/01/1996 - "It may represent a primary disturbance of insulin secretion in PCOS or may be associated with the perturbed steroid balance in anovulation. "
09/01/1993 - "This is consistent with PCO and insulin insensitivity being separate abnormalities which when combined are associated with anovulation."
08/01/1985 - "Abnormal steroid secretion may contribute to anovulation in insulin dependent diabetic patients with amenorrhoea. "
|10.||Estradiol (Estrace)FDA LinkGeneric
06/01/2013 - "Experiment 1: DEX induced anovulation (zero of five DEX vs. four of four control cows ovulated) and decreased circulating estradiol (E2). "
10/01/2012 - "These results suggest that menstrual cycle length may be a relevant indicator of estradiol exposure and risk of anovulation among regularly cycling women."
10/01/2012 - "Short ovulatory cycles were associated with higher follicular phase estradiol, an earlier rise in FSH, and an increased risk of anovulation. "
07/01/2012 - "These results suggest that the catabolic environment induced by dietary restriction may ultimately cause anovulation by reducing oestradiol synthesis, FSH-responsiveness and IGF signaling in granulosa, and LH-responsiveness in theca cells of dominant follicles."
12/01/2011 - "These include: 1) reduced circulating estradiol (E2) concentrations near estrus, 2) ovulation of follicles that are larger than the optimal size, 3) increased double ovulation and twinning, and 4) increased incidence of anovulation with a distinctive pattern of follicle growth in anovular dairy cows. "
01/01/1997 - "Transvaginal interstitial laser treatment of the ovary for the management of chronic hyperandrogenic anovulation: first clinical experience."
08/01/2006 - "The ultrasound-guided transvaginal ovarian interstitial laser treatment may be an effective new method to manage anovulation in PCOS patients."
06/01/2010 - "To explore an optimal laser dose of transvaginal ultrasound-guided ovarian interstitial laser coagulation in management of anovulation in patients with polycystic ovary syndrome (PCOS). "
01/01/1997 - "The feasibility of ultrasound-guided transvaginal interstitial laser treatment of the ovary (TILT) and its efficacy for ovulation induction was investigated in 3 hormone-therapy-resistant patients with chronic hyperandrogenic anovulation. "
01/01/1996 - "Interstitial laser treatment (ILT) of the ovary might be a new surgical approach to restore ovulation with a minimal risk of adhesion formation in patients with chronic hyperandrogenic anovulation who are unresponsive to hormone therapy. "
05/01/1998 - "Four women with PCOS whose anovulation was successfully treated with laparoscopic ovarian diathermy (LOD) underwent repeat venous sampling following LOD. "
12/01/2007 - "Laparoscopic ovarian diathermy (LOD) is one of the options for managing women with anovulation secondary to polycystic ovarian syndrome. "
05/01/2012 - "Second-line surgical interventions for anovulation associated with PCOS include laparoscopic ovarian diathermy, which is as effective as medical induction of ovulation with gonadotropins, with a much reduced risk of multiple pregnancy. "
04/01/1999 - "The objective of this study is to report retrospectively on the clinical outcome of unilateral oophorectomy in 14 women with polycystic ovary syndrome who had undergone this treatment 14-18 years ago in our hospital for clomiphene citrate-resistant anovulation and long standing infertility or for severe hirsutism. "
04/01/2005 - "Persistence of anovulation after electrocautery could be predicted and women with a high risk of persisting anovulation could be distinguished. "
04/01/2005 - "Eighty-three women with CC-resistant PCOS were allocated to receive laparoscopic electrocautery followed by CC when anovulation persisted as part of a randomized controlled trial. "
10/01/2004 - "A total of 168 CC-resistant women with PCOS were randomly assigned to receive either the electrocautery strategy, entailing laparoscopic electrocautery of the ovaries followed by CC and recombinant FSH (rFSH) if anovulation persisted, or ovulation induction with rFSH. "
01/01/1999 - "[Persistent anovulation following laparoscopic electrocoagulation of the ovarian surface in a patient with polycystic ovary syndrome (PCOS)]."
01/01/1991 - "Treatment of anovulation due to polycystic ovarian syndrome by laparoscopic ovarian electrocautery."
|5.||Contraception (Birth Control)
05/01/1995 - "Contraception during breast feeding must take two points into account: the first physiological contraception due to anovulation which disappears at around the 9th week of lactation); the second pharmacological: any substance ingested by the mother during breast feeding is excreted in milk, chiefly by passive diffusion. "
01/01/1983 - " Family planning programs should coordinate the use of contraceptive methods with lactational anovulation. "
05/01/1979 - "The problem is to reduce overlap with postpartum anovulation, during which contraception is redundant, but simultaneously to reduce the proportion of women conceiving before contraception is inaugurated. "
05/01/1966 - " Relative frequency of anovulation following oral contraception is believed greater than suspected. "
12/01/1998 - "Reduction of metabolic fuel availability below the critical level by food restriction or increased expenditure is appropriately accompanied by activations of multiple neuroendocrine-metabolic changes resulting in anovulation and amenorrhea, an important device for endogenous hypothalamic contraception. "