|5.||Weight Loss (Weight Reduction)
|1.||Laviano, Alessandro: 24 articles (08/2013 - 01/2002)|
|2.||Meguid, Michael M: 24 articles (02/2009 - 01/2002)|
|3.||Inui, Akio: 21 articles (08/2015 - 02/2002)|
|4.||Kuo, Dong-Yih: 21 articles (05/2015 - 09/2002)|
|5.||Hsieh, Yih-Shou: 15 articles (05/2015 - 04/2005)|
|6.||Hattori, Tomohisa: 14 articles (01/2015 - 06/2008)|
|7.||Asakawa, Akihiro: 14 articles (07/2013 - 02/2002)|
|8.||Langhans, Wolfgang: 13 articles (09/2013 - 01/2003)|
|9.||Rossi Fanelli, Filippo: 13 articles (08/2013 - 09/2002)|
|10.||Jatoi, Aminah: 13 articles (10/2010 - 01/2002)|
|1.||Megestrol Acetate (Borea)FDA LinkGeneric
01/01/2013 - "In addition to exercise training, administration of megestrol acetate has been proven to be effective in improving anorexia and muscle wasting in HD patients. "
05/21/2014 - "Anorexia and megestrol acetate: treatment versus placebo controlled study."
01/01/2010 - "[Treatment of uraemic anorexia with megestrol acetate]."
01/01/2006 - "Megestrol acetate use for anorexia in the older subject."
02/01/1994 - ""Treatment of anorexia with megestrol acetate"."
06/16/2010 - "[Ghrelin--new promising treatment in anorexia and catabolic conditions]."
04/01/2008 - "Further studies are necessary to confirm the efficacy of ghrelin treatment for anorexia-related disorders."
12/01/2006 - "This study provides evidence that ghrelin is an orexigenic peptide capable of antagonizing IL-1beta-induced anorexia."
12/01/2006 - "In the present study, we investigated if ghrelin could reverse IL-1beta-induced anorexia. "
10/01/2002 - "This study provides evidence of an age-related decline of plasma ghrelin concentrations, which might explain, at least partially, the somatotroph dysregulation and the anorexia of the elderly subject."
|3.||Serotonin (5 Hydroxytryptamine)IBA
02/01/2001 - "Because LPS increases CNS serotonin (5-HT) turnover, and because increases in CNS 5-HT turnover are associated with a decrease in food intake, we conducted a series of studies to examine 5-HT's potential role in LPS-induced anorexia. "
01/01/1980 - "Further studies on the mechanism of serotonin-dependent anorexia in rats."
01/01/2013 - "It is suggested that, although serotonin participates in IL-1β anorexia, other mechanisms recruited by IL-1β in normal rats are able to override the absence of the serotonergic hypophagic influence."
01/01/2013 - "These results identify CRF, UI and 5-HT as anorexigenic agents in rainbow trout, and suggest that 5-HT-induced anorexia may be at least partially mediated by CRF- and/or UI-secreting neurons. "
07/01/2012 - "The activity-based anorexia model suggests alterations in mesolimbic DA and serotonin occur as a result of restricted eating coupled with excessive wheel running. "
|4.||Cisplatin (Platino)FDA LinkGeneric
08/01/2013 - "These results suggest that RKT may have therapeutic potential for anorexia induced by cisplatin. "
01/01/2011 - "Rikkunshito, a traditional Japanese medicine, suppresses cisplatin-induced anorexia in humans."
06/01/2008 - "Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism."
06/30/2006 - "In these rats, each cisplatin injection produced both acute anorexia and rebound hyperphagic responses. "
09/02/2011 - "Rikkunshito (RKT), a Japanese traditional medicine, has been shown to stimulate food intake in rats with cisplatin-induced anorexia; however, the underlying mechanisms remain unknown. "
|5.||Adrenal Cortex Hormones (Corticosteroids)IBA
04/01/2014 - "Subjects were adult patients with life-limiting diagnoses prescribed corticosteroids for anorexia in any care setting. "
04/01/2014 - "Anorexia is a significant problem in patients approaching the end of life, for which corticosteroids are widely prescribed. "
05/01/2004 - "Successful approaches in treating anorexia have been undertaken with corticosteroids and gestagenes."
04/01/2014 - "The study objective was to identify the evidence for the use of corticosteroids, and the most safe and effective dosing regimen for management of anorexia in palliative care patients. "
04/01/2014 - "Corticosteroids are beneficial in treating anorexia in palliative care patients with malignancies; however there is no evidence for their use in anorexia due to end-stage nonmalignant disease. "
|6.||Granisetron (Kytril)FDA LinkGeneric
01/01/2011 - "X-ray and chemotherapeutic agents induced anorexia in all rats, but anorexia was not recovered by pretreatment with granisetron. "
08/01/1996 - "Complete control of anorexia was achieved in 91.6% (11/12 cases) of patients receiving the combination compared to 58.3% (7/12 cases) of patients receiving granisetron alone. "
12/01/1994 - "[Clinical effects of granisetron and methylpredonisolone against delayed emesis and anorexia induced by anticancer agents]."
08/01/2003 - "There is evidence to suggest that there is a significant trend towards an improved efficacy of granisetron-in both the control of emesis and secondary end-points such as nausea and anorexia-with increasing doses, up to 40 micro g/kg, in adults. "
08/01/1996 - "Moreover there was a significant improvement of delayed clinical symptoms including nausea, vomiting, and anorexia in the patients receiving the combination of granisetron plus MPL. "
07/01/1991 - "In particular, the frequency of leukopenia was a high 75.5%, while there was a decrease in hemoglobin in 38.8% and anorexia in 30.6%. "
07/01/1987 - "Clinical signs included lethargy, anorexia, and weakness; hemoglobin was 6.8 g/dl, PCV was 21%, and WBC was 1,500/dl. "
10/01/2014 - "The common adverse drug reactions were a decrease in hemoglobin levels, hypoalbuminemia, and anorexia, which were mild in severity (grades 1-2). "
04/01/2008 - "The major adverse events were anorexia, fatigue, hemoglobin reduction, nausea and pigmentation change, although most were tolerable and reversible. "
06/01/2007 - "Major adverse reactions included a decreased hemoglobin level, diarrhea, nausea and anorexia of grade 3 or worse (each occurred in 10% of the patients). "
|8.||Tryptophan (L-Tryptophan)FDA Link
04/01/2007 - "Attenuation of stress-induced anorexia in brown trout (Salmo trutta) by pre-treatment with dietary l-tryptophan."
01/01/2002 - "The development and severity of depressive symptoms, especially anorexia, pessimistic thoughts, suicidal ideation and loss of concentration were positively correlated with the magnitude of the decreases in tryptophan concentrations during treatment. "
01/01/1998 - "The decreases of both food intake and growth rate were smaller in tryptophan injected (food intake 23.9% p<0.05; growth rate 2.9% p<0.05) than saline injected (food intake 78.5% p<0.01; growth rate 6.1% p<0.01) rats suggesting that tryptophan administration inhibits restraint-induced anorexia. "
01/01/1998 - "Inhibition of restraint-induced anorexia by injected tryptophan."
01/01/1996 - "Tryptophan and secondary anorexia."
12/01/2014 - "Activity-based anorexia (ABA) is a rodent model of AN that shares symptoms with AN, including over-exercise, elevation of stress hormones, and genetic links to anxiety traits. "
01/01/2013 - "Anorexia of aging and gut hormones."
05/01/2009 - "The impaired response of these hunger regulatory hormones with age might contribute to the mechanisms of anorexia associated with aging."
09/01/2008 - "Thus, alterations in taste and smell, gastric motility, intestinal overgrowth and changes in gastrointestinal hormone release are the basis of the physiological anorexia of aging. "
09/01/2005 - "Moreover, we determined whether circulating levels of other gut hormones are modulated by OEA and whether CCK is involved in OEA-induced anorexia. "
|10.||Dopamine (Intropin)FDA LinkGeneric
06/18/1986 - "Behavioural studies have shown that the perifornical hypothalamus (PFH) plays a fundamental role in mediating dopamine-induced anorexia. "
01/01/2015 - "Dopamine D2/3 receptor antagonism reduces activity-based anorexia."
03/01/2009 - "These data support a role for dopamine in anorexia associated hyperactivity. "
12/17/2003 - "Previously, using daily food intake (DFI) as an indicator, we found that both dopamine (DA) D1 and D2 receptors were involved in AMPH anorexia. "
02/01/2003 - "Furthermore, food restriction in animals and anorexia in humans is associated with impaired dopamine signaling. "
|1.||Drug Therapy (Chemotherapy)
08/01/2015 - "Moreover, the pre-chemotherapy total energy intake, measured according to the hospital meal consumption of patients, was lower among those with than among those without anorexia. "
06/01/2015 - "The frequency of grade 3 chemotherapy-induced anorexia was higher in patients with CC than those without CC at T2 (15.4 vs. 0.0 %, P = 0.0044). "
03/01/2015 - "We tested these agents in combination, in a pilot study to assess tolerability in patients indicating 4/10 or worse anorexia on the Edmonton Symptom Assessment System, and who were not currently on chemotherapy. "
09/09/2014 - "Grade 2 anorexia was the most frequent chemotherapy-related toxicity and no toxic death was noted. "
08/06/2013 - "Grade 3/4 toxicities during the S-1 chemotherapy included anaemia (7.3%), neutropaenia (3.7%), and anorexia (3.7%). "
|2.||Palliative Care (Palliative Medicine)
01/01/2014 - "This study aimed at establishing the frequency of anorexia-cachexia, as well as its relationship to GI symptoms in the context of palliative care patients at the Instituto Nacional de Cancerología, México City. "
05/01/2010 - "It has also been studied in the palliative care of patients with cytokine-based syndromes such as anorexia-cachexia syndrome. "
09/01/2008 - "[Anorexia-cachexia in palliative care]."
12/01/2001 - "Clinicians involved in oncology and hospice/palliative care should have a clear understanding of this process and appropriate interventions for patients experiencing anorexia/cachexia."
09/01/2000 - "Anorexia is one of the most frequent complaints in patients who have reached the palliative-care phase of lung cancer. "
01/01/2013 - "The mechanism of action for anorexia, which continues during or after treatment, is, however, still unclear. "
03/01/1985 - "A long lasting anorectic effect was observed for 20 U/kg of sCT with a parallelism between hypocalcaemia and anorexia in the first 8 hours after treatment; on the contrary, rats continued to eat less than controls in the following hours when their serum Ca++ concentrations had risen to normal or even higher levels. "
12/01/2009 - "Symptoms as oral greasy-sticky, thirsty, asthenia, abdominal distension and anorexia were improved after treatment in both groups (P < 0.05). "
09/01/2012 - "The ratios of anorexia and nausea in patients of the treatment group was lowered after treatment (P<0.05). "
07/15/1980 - "Mild to severe colic was observed up to six hours after treatment, diarrhoea and/or anorexia continuing to be present for one to six days after administration. "
|4.||Enteral Nutrition (Feeding, Tube)
05/01/2013 - "Dogs with NE tubes were significantly younger than dogs with NG tubes (P = 0.03) but there were no other significant differences in signalment, underlying disease, medications, duration of anorexia, percent of resting energy requirement achieved, or change in weight during tube feeding. "
02/01/2008 - "These effects were not linked to anorexia, since they were observed when rats were fed using continuous enteral nutrition. "
02/01/2008 - "Since TBI leads to a profound anorexia, in a second set of experiments TBI rats received enteral nutrition (TBI-EN group) for 4 days to specifically assess the role of anorexia in the hepatic disturbances. "
04/11/1992 - "Furthermore, we have observed additional marked loss of bone mass under tube feeding in underweight anorexia patients. "
04/11/1992 - "[Loss of bone mass in patients with anorexia on tube feeding and its prevention with biphosphonates]."
|5.||Nutritional Support (Artificial Feeding)
01/01/2011 - "Nutritional assessment and institution of nutritional support is crucial because dialysis only partially alleviates uremic anorexia. "
01/01/1987 - "Anorexia is of prime importance, differing in its cause from one patient to another and often presenting a barrier to successful nutritional support. "
12/01/2008 - "An eight-day admission within an each course to CDDP treatment and nutritional support were required for adverse events of anorexia (grade 3), but for other days home chemotherapy was done with good compliance of S-1 up to 6 courses. "
10/01/2001 - "Supplemental enteral feeds using a gastrostomy tube (G-tube) are commonly used for nutritional support to overcome the barrier posed by anorexia. "
05/01/2004 - "Early intervention and nutritional support may be helpful in preventing anorexia and further weight loss. "