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Angiotensinogen

An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver and secreted into blood circulation. Angiotensinogen is the inactive precursor of natural angiotensins. Upon successive enzyme cleavages, angiotensinogen yields angiotensin I, II, and III with amino acids numbered at 10, 8, and 7, respectively.
Also Known As:
Proangiotensin; Renin Substrate Tetradecapeptide; Serpin A8; Renin Substrate; Tetradecapeptide, Renin Substrate; Hypertensinogen; Renin-Substrate; Angiotensinogen (protein renin substrate)
Networked: 1430 relevant articles (10 outcomes, 250 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kobori, Hiroyuki: 47 articles (06/2015 - 02/2002)
2. Urushihara, Maki: 18 articles (06/2015 - 08/2008)
3. Navar, L Gabriel: 17 articles (08/2015 - 02/2002)
4. Nishiyama, Akira: 15 articles (04/2015 - 01/2003)
5. Ohashi, Naro: 14 articles (11/2015 - 05/2007)
6. Sigmund, Curt D: 13 articles (07/2013 - 02/2002)
7. Ingelfinger, Julie R: 10 articles (10/2015 - 12/2002)
8. Satou, Ryousuke: 10 articles (08/2015 - 06/2007)
9. Kumar, Ashok: 10 articles (02/2015 - 09/2002)
10. Lalouel, Jean-Marc: 10 articles (06/2012 - 01/2002)

Related Diseases

1. Hypertension (High Blood Pressure)
2. Pre-Eclampsia (Preeclampsia)
3. Anoxia (Hypoxia)
4. Obesity
5. IGA Glomerulonephritis (IGA Nephropathy)

Related Drugs and Biologics

1. Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
2. Renin
3. Messenger RNA (mRNA)
4. Angiotensins
5. Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
6. candesartan
7. Endothelins (Endothelin)
8. eplerenone (Inspra)
9. bosentan (Tracleer)
10. Type 1 Angiotensin Receptor

Related Therapies and Procedures

1. Transplants (Transplant)
2. Kidney Transplantation
3. Ligation
4. Heart Transplantation (Grafting, Heart)
5. Coronary Balloon Angioplasty (Percutaneous Transluminal Coronary Angioplasty)