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Unstable Angina

Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
Also Known As:
Angina, Unstable; Anginas, Preinfarction; Anginas, Unstable; Myocardial Preinfarction Syndromes; Preinfarction Angina; Preinfarction Anginas; Preinfarction Syndrome, Myocardial; Preinfarction Syndromes, Myocardial; Syndrome, Myocardial Preinfarction; Syndromes, Myocardial Preinfarction; Unstable Anginas; Angina at Rest; Angina, Preinfarction; Myocardial Preinfarction Syndrome
Networked: 4720 relevant articles (297 outcomes, 935 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Myocardial Infarction
2. Acute Coronary Syndrome
3. Coronary Artery Disease (Coronary Atherosclerosis)
4. Chest Pain (Chest Pains)
5. Stroke (Strokes)

Experts

1. Cannon, Christopher P: 27 articles (09/2015 - 10/2002)
2. Roe, Matthew T: 26 articles (06/2015 - 12/2002)
3. Ohman, E Magnus: 24 articles (08/2013 - 08/2002)
4. Peterson, Eric D: 20 articles (06/2015 - 06/2003)
5. Harrington, Robert A: 19 articles (11/2014 - 01/2002)
6. Murphy, Sabina A: 18 articles (09/2015 - 07/2002)
7. Califf, R M: 18 articles (04/2015 - 01/2000)
8. Crea, Filippo: 18 articles (09/2009 - 07/2002)
9. Topol, E J: 18 articles (12/2001 - 01/2000)
10. Braunwald, Eugene: 17 articles (10/2013 - 02/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Unstable Angina:
1. Heparin (Liquaemin)FDA LinkGeneric
2. Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
3. Glycoproteins (Glycoprotein)IBA
4. Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
5. CalciumIBA
6. Diltiazem (Cardizem)FDA LinkGeneric
7. Enoxaparin (Lovenox)FDA LinkGeneric
8. tirofiban (Aggrastat)FDA Link
9. Nitroglycerin (Dynamite)FDA LinkGeneric
10. clopidogrel (Plavix)FDA Link
03/15/2005 - "The efficacy of platelet inhibition with clopidogrel for up to one year after ACS was demonstrated in the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial, a randomized trial of 12,562 patients in 28 countries that was conducted between 1998 and 2000. "
10/01/2013 - "This study aimed to evaluate the impact of PON1 Q192R in parallel to that of CYP2C19*2 (rs4244285) on clopidogrel responsiveness in a cohort of Chinese patients with unstable angina pectoris. "
10/30/2012 - "With the use of the Clopidogrel in Unstable Angina to Prevent Recurrent Events trial for Plavix as an example, this article proposes Multiple Comparisons with Control (Subgroup) and Multiple Comparisons with the Best (Subgroup) as methods to infer whether some subgroups of patients derive more or less benefit than wild-type patients and which subgroup or subgroups of patients derive maximum benefit or practically maximum benefit from the drug."
03/01/2012 - "Randomized studies were post hoc analyses of the Clopidogrel as Adjunctive Reperfusion Therapy (CLARITY), Clopidogrel for the Reduction of Events During Observation (CREDO), and Clopidogrel in Unstable Angina to Prevent Recurrent Ischemic Events trials. "
07/01/2008 - "Our objective was to conduct a comprehensive cost-effectiveness analysis of pre-treatment and long-term treatment with clopidogrel in percutaneous coronary intervention (PCI) in three European countries based on a meta-analysis of the PCI-Clopidogrel in Unstable angina to prevent Recurrent Events (CURE), Clopidogrel for the Reduction of Events During Observation (CREDO) and PCI-Clopidogrel as Adjunctive Therapy (CLARITY) trials. "

Therapies and Procedures

1. Angioplasty (Angioplasty, Transluminal)
2. Coronary Balloon Angioplasty (Percutaneous Transluminal Coronary Angioplasty)
3. Stents
4. Coronary Artery Bypass (Coronary Artery Bypass Surgery)
5. Transplants (Transplant)