Aminoimidazole Carboxamide

An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.

Also Known As:

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ahn, Soon-Cheol: 1 article (01/2017)
2.	Baek, Su Youn: 1 article (01/2017)
3.	Jang, Mi Hee: 1 article (01/2017)
4.	Kim, Joung-Hee: 1 article (01/2017)
5.	Kim, Keuk-Jun: 1 article (01/2017)
6.	Kim, Kwang-Youn: 1 article (01/2017)
7.	Kim, Sang Chan: 1 article (01/2017)
8.	Kim, Young Woo: 1 article (01/2017)
9.	Lee, Eun Hye: 1 article (01/2017)
10.	Lee, Hyeong Sik: 1 article (01/2017)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 01/25/2017 - "FLL treatment significantly blocked these pathological changes and the mitochondrial dysfunction caused by AA + iron, which were similar with the effect of aminoimidazole-carboxamide-β-d-ribofuranoside (AICAR). "
2.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 10/01/1999 - "Abbreviations used are: tRNA-transfer ribonucleic acid, TMS-trimethylsilyl, RP-HPLC--reverse phase high performance liquid chromatography, EI--electron impact, cm5U-5-carboxymethyluridine, mcm5U-5-methoxycarbonylmethyluridine, cm5s2U-5-carboxymethyl-2-thiouridine, mcm5s2U-5-methoxycarbonylmethyl-2-thiouridine, t6A-9-beta-D-ribofuranosyl-[N(purin-6-yl)carbamoyl]-1-threonine, C-cytidine, acp3u-3-(3-amino-3-carboxypropyl)uridine, AICR-aminoimidazole carboxamide riboside, alpha-4-PCNR & beta-4-PCNR-9-alpha-D-(or beta-D)-ribofuranosyl-pyridin-4-one-3-carboxamide, H x 7R-7-beta-D-ribofuranosyl hypoxanthine, m3U-3-methyluridine, m1I-1-methylinosine, m1G-1-methylguanosine, DI-5'-deoxyinosine, dms5OA-5'-deoxy-5'-methylthioadenosine sulfoxide, m2(2)G-N2-dimethylguanosine, psi-psi-uridine, A-adenosine, I-inosine, CML-chronic myelogenous leukemia mam5s2U-5-methylaminomethyl-2-thiouridine, ncm5U-5-carbamoylmethyluridine, ncm5s2U-5-carbamoylmethyl-2-thiouridine, UV-ultraviolet, NMR-nuclear magnetic resonance, HPLC-high performance liquid chromatography, GC-MS-gas chromatography-mass spectrometry."
3.	Fatty Liver 05/01/1965 - "The effects of inosine and aminoimidazole carboxamide upon the ethionine fatty liver."
4.	Body Weight (Weight, Body) 01/01/2013 - "Rats were fed a control (C), or a high fat (HF) diet (60% fat) for 6 weeks and injected with saline or a daily aminoimidazole carboxamide ribnucleotide (AICAR) dose of 0.5 mg/g body weight. "
5.	Experimental Arthritis 08/01/1998 - "The effect of methotrexate and 7-hydroxymethotrexate on rat adjuvant arthritis and on urinary aminoimidazole carboxamide excretion."

Related Drugs and Biologics

1.	Inosine
2.	AICA ribonucleotide (ZMP)
3.	Hypoxanthine
4.	Uridine
5.	Threonine (L-Threonine)
6.	Transfer RNA (tRNA)
7.	RNA (Ribonucleic Acid)
8.	Methotrexate (Mexate)
9.	Ethionine
10.	Cytidine