|4.||Amebic Liver Abscess
|1.||Petri, William A: 15 articles (01/2014 - 10/2002)|
|2.||Orozco, Esther: 8 articles (01/2013 - 02/2005)|
|3.||Chadee, Kris: 8 articles (02/2009 - 09/2002)|
|4.||Nozaki, Tomoyoshi: 7 articles (01/2015 - 10/2003)|
|5.||Tannich, Egbert: 7 articles (12/2013 - 12/2004)|
|6.||Haque, Rashidul: 6 articles (04/2013 - 02/2006)|
|7.||Marchat, Laurence A: 5 articles (08/2015 - 08/2008)|
|8.||Azam, Amir: 5 articles (11/2014 - 06/2005)|
|9.||Houpt, Eric: 5 articles (05/2013 - 02/2006)|
|10.||Bhattacharya, Alok: 5 articles (01/2011 - 03/2004)|
|1.||Metronidazole (Metric)FDA LinkGeneric
01/01/1976 - "Metronidazole is a drug of proven efficacy in amoebiasis; however its use is restricted in patients who cannot take the drug by mouth, because of severe complications of the disease. "
02/01/1984 - "We found metronidazole effective in the treatment of both pyogenic and amebic abscesses."
06/01/2009 - "The aim was to evaluate the efficacy of Saccharomyces boulardii (Sb) in addition to metronidazole in amebiasis. "
08/01/2000 - "He had been treated for amebiasis with metronidazole, and had improved. "
04/02/2002 - "Studies on the development of oral colon targeted drug delivery systems for metronidazole in the treatment of amoebiasis."
01/01/2008 - "histolytica antigens via T3SS may constitute a suitable oral vaccine carrier against amoebiasis and that an effective IFN-gamma response is required for protection against invasive amoebiasis."
07/01/2007 - "Therefore, the stimulation of intestinal secretory response by mucosal delivery of amoebic antigens has been positioned as a promising strategy for inducing protection against human amoebiasis."
01/01/1998 - "histolytica, and find out antigens which have both immunodiagnostic and prophylactic potential against amoebiasis. "
02/01/2015 - "We concluded that EhMSP-1 is a promising antigen that warrants further study to determine its full potential as a target for therapy and/or prevention of invasive amebiasis. "
09/01/2002 - "The results of the study suggest that the 35-kDa polypeptide antigen can be a diagnostic marker in active amoebiasis."
01/01/1962 - "[Colo-hepato-pulmonary amebiasis: complete clinical cure with 2-dehydro-emetine]."
12/01/1957 - "[Amebic abscess of right lobe apparently cured by emetine; value of gammagraphy & colored laparophotography]."
01/01/2013 - "Emetine dihydrochloride hydrate, an anti-protozoal drug previously used for intestinal and tissue amoebiasis was shown to have potent inhibitory properties (IC₅₀ doses of ~ 47 nM) in the multidrug resistant K1 strain of P. "
10/01/1966 - "[2-Dehyro-emetine administered orally in the treatment of amebiasis. "
05/01/1965 - "[2-Dehydro-emetine administered orally in the treatment of amebiasis. "
|4.||Chloroquine (Aralen)FDA LinkGeneric
01/01/1952 - "[Hepatic amebic abscess cured with chloroquine (Baskir compound)]."
05/01/1964 - "[DIAGNOSIS OF AMEBIC ABSCESS OF THE LIVER BY THE CHLOROQUINE THERAPEUTIC TEST]."
05/01/1962 - "[Chloroquine therapy of amebic abscess of the liver]."
01/01/1954 - "[Amebic abscess of the liver; report of two cases treated with puncture and aspiration, using chloroquine locally and orally]."
07/01/1953 - "Pulmonary amoebiasis; with particular reference to chloroquine therapy."
05/01/1976 - "The excellent results obtained in this trial indicate that tinidazole is a drug worthy of extensive evaluation in the treatment of amoebiasis, as three single daily doses is a simple form of treatment. "
01/01/1983 - "We cannot, therefore, recommend tinidazole alone in this dosage as a treatment for non-invasive amoebiasis."
05/01/1976 - "Clinical evaluation in tinidazole in amoebiasis in children."
07/01/1973 - "Tinidazole in amoebiasis."
01/01/1978 - "Tinidazole has been reported to be highly effective against trichomoniasis, giardiasis and amoebiasis. "
|6.||diloxanide furoate (diloxanide)IBA
02/01/1962 - "Comparative experiments on both activity and toxicity were carried out on M&B 4321 and diloxanide, since the latter compound had already been administered safely to man and had shown good activity against non-dysenteric amoebiasis. "
07/01/1964 - "[ENTAMIDE FUROATE IN THE TREATMENT OF COLIC AMEBIASIS]."
12/26/1981 - "In amebiasis a luminal amebicide (diloxanide furoate) was prescribed in all instances after the first stool examination. "
07/01/1977 - "Treatment of amoebiasis with metronidazole and entamide furoate."
05/01/1997 - "Efficacy of a combined diloxanide furoate-metronidazole preparation in the treatment of amoebiasis and giardiasis."
|7.||Chlortetracycline (Aureomycin)FDA Link
09/10/1961 - "[The treatment of chronic amebiasis with demethyl-chlortetracycline]."
07/01/1952 - "[Aureomycin therapy of amebiasis; findings and evaluation of a fatal case with localizations in the colon, liver and lungs]."
04/01/1952 - "[Aureomycin therapy of amebiasis]."
03/01/1952 - "A long term evaluation of aureomycin in the treatment of amebiasis."
07/23/1951 - "[Treatment of amebiasis with aureomycin]."
07/01/2004 - "This study identifies the lectin epitopes to be studied in an amebiasis subunit vaccine designed to elicit mucosal immunity mimicking that of humans cured of ALA."
09/01/1995 - "Identification of immunogenic epitopes of the 170-kDa subunit adhesin of Entamoeba histolytica in patients with invasive amebiasis."
05/19/1997 - "These studies should enable us to develop an improved vaccine for amebiasis, and provide a model for the identification of protective and exacerbative epitopes of complex antigens."
08/01/2007 - "We designed an amebiasis subunit vaccine that is constructed by using four peptide epitopes of the galactose-inhibitable lectin heavy subunit that were recognized by intestinal secretory immunoglobulin A (IgA) antibodies from immune human subjects. "
08/01/1988 - "An open study was carried out to determine the clinical efficacy of secnidazole in the treatment of acute and chronic cases of amoebiasis. "
08/01/1988 - "Efficacy of a single dose of secnidazole in the treatment of acute and chronic amoebiasis."
07/01/1976 - "In view of these findings, the advantages which secnidazole might possess over other 5-nitroimidazoles already in use for the treatment of amebiasis and trichomoniasis are discussed."
03/01/1999 - "Secnidazole response in amoebiasis and giardiasis."
01/08/2009 - "Secnidazole (alpha,2-dimethyl-5-nitro-1H-imidazole-1-ethanol) is an antimicrobical drug, and it is particularly effective in the treatment of amebiasis, giardiasis, trichomoniasis, and bacterial vaginosis. "
|10.||Anti-Bacterial Agents (Antibiotics)IBA
04/01/2011 - "Nitroimidazole antibiotics are the mainstay of treatment of invasive amebiasis; however, few comparative studies of applicable antibiotics are available. "
08/01/2003 - "To compare the efficacy of antibiotics therapy alone with antibiotics and saccharomyces boulardii in treatment of acute amebiasis. "
08/01/2003 - "Efficacy of saccharomyces boulardii with antibiotics in acute amoebiasis."
09/01/1966 - "[Antibiotics in the therapy of amebiasis]."
03/27/1965 - "[ANTIBIOTICS IN THE TREATMENT OF AMEBIASIS]."
|1.||Drug Therapy (Chemotherapy)
05/01/1989 - "It is expected that this model will be useful to study host-parasite interactions, immunology and experimental chemotherapy of amoebiasis."
09/01/2012 - "[Current pharmacotherapy of amebiasis, advances in new drugs, and design of a vaccine]."
04/01/1999 - "histolytica may provide novel approaches for the chemotherapy of invasive amoebiasis."
10/01/1990 - "It is expected that this model might be useful in studying various parameters of host-parasitic interactions and experimental chemotherapy of amoebiasis with relative ease."
09/01/1980 - "The chemotherapy of amoebiasis."
07/09/2008 - "The aim of the research work was to develop cyst-targeted novel concanavalin-A (Con-A) conjugated mucoadhesive microspheres of diloxanide furoate (DF) for the effective treatment of amoebiasis. "
01/01/2013 - "The objective of this study is to develop stable, biodegradable chitosan-sodium alginate-based dual, ionic cross-linked multiparticulate system (microbeads) of tinidazole for targeted colon delivery and sustained drug release for the treatment of amoebiasis and thereby evaluating its targeting approach through in vivo gamma scintigraphic imaging technique. "
06/01/2012 - "The nitroimidazole compounds are the mainstay of treatment for giardia and amebiasis with no major advance in therapeutics since their role was appreciated. "
01/01/2011 - "The monocyte locomotion inhibitory factor an anti-inflammatory peptide; therapeutics originating from amebic abscess of the liver."