|1.||Sundsfjord, Arnfinn: 3 articles (02/2016 - 01/2013)|
|2.||Lindbæk, Morten: 2 articles (07/2014 - 01/2014)|
|3.||Søraas, Arne: 2 articles (01/2014 - 01/2013)|
|4.||Jenum, Pål A: 2 articles (01/2014 - 01/2013)|
|5.||Småbrekke, Lars: 1 article (02/2016)|
|6.||Zykov, Ilya Nikolaevich: 1 article (02/2016)|
|7.||Samuelsen, Ørjan: 1 article (02/2016)|
|8.||Kahlmeter, Gunnar: 1 article (12/2015)|
|9.||Zimmermann, S: 1 article (12/2015)|
|10.||Åhman, Jenny: 1 article (12/2015)|
01/01/1982 - "The steady-state volume of distribution was calculated to be 0.26 liter/kg. Urinary concentrations of amdinocillin were far in excess of the usual inhibitory concentrations for susceptible pathogens and were as high as 3,000 micrograms/ml. Dose of amdinocillin every 4 h provide plasma and urine concentrations which should be effective for the treatment of infections."
01/01/1988 - "It is concluded that the activity of amdinocillin alone or in combination with another beta-lactam antibiotic should not be more effective in the treatment of infections by gram-negative bacilli than just using the beta-lactam antibiotic alone at a higher dose."
08/29/1983 - "Eleven of 15 infections responded favorably to amdinocillin, and seven were cured. "
08/29/1983 - "Efficacy of amdinocillin and lack of nephrotoxicity when combined with a second beta-lactam antibiotic for therapy of serious gram-negative bacillary infections."
01/01/1979 - "The five patients with septicaemia were all cured of their infection, this result being attributed solely to mecillinam in two cases, while a combined action of mecillinam and another antibiotic produced a cure in the other three cases. "
|2.||Urinary Tract Infections (Urinary Tract Infection)
01/01/1985 - "Amdinocillin, as a single agent, is effective in the treatment of urinary tract infections caused by susceptible strains of E. "
01/01/2014 - "A population-based study was performed to investigate the efficacy of mecillinam treatment of community-acquired urinary tract infections (CA-UTI) caused by extended-spectrum β-lactamase (ESBL) producing Escherichia coli. "
01/01/2014 - "High rate of per oral mecillinam treatment failure in community-acquired urinary tract infections caused by ESBL-producing Escherichia coli."
11/01/1998 - "We conclude that mecillinam should be reevaluated for potential use in the treatment of community-acquired urinary tract infections."
08/29/1983 - "It was concluded that amdinocillin is a satisfactory antibiotic for the treatment of complicated urinary tract infections with susceptible organisms."
10/01/2012 - "Mecillinam may be useful in uncomplicated cystitis caused by ESBL producers with low MICs. "
04/01/1987 - "We studied the transfer of mecillinam into the serum, and found that the extent of transfer varied with the method to cause experimental cystitis and also occurred even in the normal bladder. "
01/01/2014 - "Ibuprofen versus mecillinam for uncomplicated cystitis--a randomized controlled trial study protocol."
07/01/2014 - "In the targeted emergency department, there was a significant (p < 0.0001) reduction in ciprofloxacin prescribing for cystitis, while the use of mecillinam increased (p = 0.042). "
01/01/2014 - "If treatment of uncomplicated cystitis with ibuprofen is as effective as mecillinam for symptom relief, we can potentially reduce the use of antibiotics on a global scale. "
|4.||Typhoid Fever (Typhoid)
07/01/1977 - "In vitro studies carried out in this Department confirmed the high activity of mecillinam against Salmonella spp. As a result we set up a study to investigate the efficacy of mecillinam in patients suffering from enteric fever. "
03/03/1979 - "Twelve consecutive patients with enteric fever entered a trial of 14 days' treatment with mecillinam. "
08/29/1983 - "Management of enteric fever with amdinocillin."
07/01/1980 - "Mecillinam and enteric fever."
03/03/1979 - "Although all organisms recovered were fully sensitive to mecillinam, this drug is not an effective or consistent treatment for enteric fever."
01/01/1981 - "The resistance of mecillinam of Escherichia coli strain RF292, which was isolated from a patient during relapse of septicemia, was investigated. "
09/01/1987 - "Chemotherapeutic efficacy of mecillinam and dioxidine was studied on a model of Escherichia coli septicemia of albino mice caused by polyresistant variants of E. "
01/01/1980 - "Of 20 patients with gram-negative septicemia treated with mecillinam alone or in combination with ampicillin, successful therapeutic results were obtained in 16. "
01/01/1980 - "Mecillinam and ampicillin separately or combined in gram-negative septicemia."
09/01/1980 - "Mecillinam or a placebo was added to a combination of cefazolin and carbenicillin as an early therapy of septicemia caused by gram-negative organisms in patients with serious underlying diseases, none of whom was neutropenic, however. "
|1.||Cefoxitin (Cefoxitin Sodium)
|2.||Anti-Bacterial Agents (Antibiotics)
|3.||Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)
|5.||Amdinocillin Pivoxil (Pivmecillinam)
|8.||Thymidine Monophosphate (TMP)
|2.||Renal Dialysis (Hemodialysis)
|3.||Drug Therapy (Chemotherapy)