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Ambroxol (Mucosolvan)

163  relevant articles (18 outcomes, 32 trials/studies) found for this Bio-Agent

Description: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.

Also Known As:
Mucosolvan; 4-(((2-Amino-3,5-dibromophenyl)methyl)amino)cyclohexanol; AMBROPP; Abrohexal; Ambril; Ambro-Puren; Ambrobeta; Ambrofur; Ambrohexal; Ambrolitic; Ambrolös; Ambroten; Ambroxin; Ambroxocompren; Berlin-Chemie Brand of Abmbroxol Hydrochloride; Betapharm Brand of Ambroxol Hydrochloride; Bisolvon AM; Boehringer Ingelheim Brand of Ambroxol Hydrochloride; Bronchopront; Bronchowern; Broxol; Carnot Brand of Ambroxol Hydrochloride; Cascan Brand of Ambroxol Hydrochloride; Chiesi Brand of Ambroxol Hydrochloride; Contac Husten-Trunk; Degort's Brand of Ambroxol Hydrochloride; Diba Brand of Ambroxol Hydrochloride; Dinobroxol; Duramucal; Ebromin; Esparma Brand of Ambroxol Hydrochloride; Europharma Brand of Ambroxol Hydrochloride; Expeflen; Expit; Farmabroxol; Farmasan Brand of Ambroxol Hydrochloride; Flavamed; Frenopect; Fustery Brand of Ambroxol Hydrochloride; Gelopol; Glaxo Wellcome Brand of Ambroxol Hydrochloride; Hefa Brand of Ambroxol Hydrochloride; Hexal Brand of Ambroxol Hydrochloride; Isis Brand of Ambroxol Hydrochloride; Larylin Husten-Löser; Lasolvan; Lichtenstein Brand of Ambroxol Hydrochloride; Mack Brand of Ambroxol Hydrochloride; Marjan Brand of Ambroxol; Merck Brand of Ambroxol Hydrochloride; Mibrox; Motosol; Muco-Fips; Mucotablin; NA-872; Nattermann Brand of Ambroxol Hydrochloride; Orion Brand of Ambroxol Hydrochloride; Pect Hustenlöser; Promeco Brand of Ambroxol Hydrochloride; Pulmonal S; Pulmopharm Brand of Ambroxol Hydrochloride; Pädia Brand of Ambroxol; Pädiamuc; Rentschler Brand of Ambroxol Hydrochloride; Ringelheimer Pulmonal; Sankyo Brand of Ambroxol Hydrochloride; Schaper & Brümmer Brand of Ambroxol Hydrochloride; Sekretovit; SmithKline Beecham Brand of Ambroxol Hydrochloride; Stada Brand of Ambroxol Hydrochloride; Surbronc; Teva Brand of Ambroxol Hydrochloride; Therapin Hustenlöser; Thomae Brand of Ambroxol Hydrochloride; Wernigerode Brand of Ambroxol Hydrochloride; stas-Hustenlöser; AM, Bisolvon; Ambro Puren; AmbroPuren; Ambroxol Marjan Brand; Ambroxol Pädia Brand; Berlin Chemie Brand of Abmbroxol Hydrochloride; Contac Husten Trunk; Contac HustenTrunk; Hustenlöser, Pect; Hustenlöser, Therapin; Larylin Husten Löser; Larylin HustenLöser; Metabolite VIII, Bromhexine; Muco Fips; MucoFips; NA 872; NA872; Pulmonal, Ringelheimer; stas Hustenlöser; stasHustenlöser; Bromhexine Metabolite VIII; Cyclohexanol, 4-(((2-amino-3,5-dibromophenyl)methyl)amino)-, trans-

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gillissen, Adrian: 2 articles (11/2005 - 01/2002)
2. Pschorn, Uwe: 2 articles (01/2002 - 01/2002)
3. Peil, Hubertus: 2 articles (01/2002 - 01/2002)
4. Aicher, Bernhard: 2 articles (01/2002 - 01/2002)
5. Müller, Achim: 2 articles (01/2002 - 01/2002)
6. de Mey, Christian: 2 articles (01/2002 - 01/2002)
7. Dai, Hong-song: 1 article (09/2007)
8. Bachet, P: 1 article (10/2006)
9. Giannoli, C: 1 article (10/2006)
10. Vial, T: 1 article (10/2006)

Related Diseases

1. Syndrome
2. Cough
3. Chronic Bronchitis
4. Pain (Aches)
12/01/2005 - "Ambroxol (1g/kg) was only weakly effective in models for acute pain, but effectively reduced pain symptoms in all other models; in some cases it completely reversed pain behaviour. "
01/01/2002 - "RESULTS: All treatments led to a reduction of pain intensity; the means (+/- SD) SPIDnorm after the 1st lozenge were 0.53 +/- 0.28 or 0.50 +/- 0.30 or 0.38 +/- 0.28 with 20 mg or 30 mg ambroxol hydrochloride or placebo respectively in study I, and 0.53 +/- 0.30 or 0.60 +/- 0.28 or 0.39 +/- 0.31 in study II; the effect of treatment was statistically significant (p: 0.0002 or p: 0.0033 in study I and p: 0.0005 or p: 0.0001 in study II, respectively, for the comparison of 20 mg or 30 mg ambroxol hydrochloride vs. placebo). "
01/01/2008 - "Detailed investigations of ambroxol with modern pharmacological methods yielded additional interesting results: ambroxol has been found to have profound effects on neuronal voltage-gated Na(+), as well as Ca(2+) channels, and to effectively reduce chronic inflammatory and neuropathic pain in rodents. "
12/01/2005 - "Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain."
01/01/2002 - "RESULTS: Both treatments led to a reduction of pain intensity; the mean (+/- SD) SPIDnorm after the 1st lozenge were 0.39 +/- 0.27 and 0.28 +/- 0.25 for 20 mg ambroxol hydrochloride and placebo, respectively; the treatment effect of ambroxol was statistically significantly superior compared to placebo (p: 0.0029; 95% confidence interval estimate of the mean treatment difference for ambroxol minus placebo: 0.04 to 0.18). "
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5. Pharyngitis (Sore Throat)

Related Drugs and Biologics

1. Cyclohexanols
2. Acetylcysteine (Siran)
3. Methacholine Chloride (Methacholine)
4. Carbocysteine (S-Carboxymethylcysteine)
5. Placebos
6. Amoxicillin (Wymox)
7. ditec
8. Ambroxol (Mucosolvan)
9. Steroids
10. Betamethasone (Celestone)

Related Therapies and Procedures

1. Artificial Respiration (Mechanical Ventilation)
2. Intravenous Infusions
3. Aftercare (After-Treatment)
4. Oral Administration
5. Transplants (Transplant)

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