|1.||Yuki, Nobuhiro: 13 articles (12/2015 - 03/2002)|
|2.||Kuwabara, Satoshi: 13 articles (01/2015 - 03/2002)|
|3.||Suzuki, Hiroshi: 13 articles (04/2010 - 01/2002)|
|4.||Saito, Reiko: 13 articles (04/2010 - 01/2002)|
|5.||Suzuki, Yasushi: 9 articles (04/2010 - 09/2006)|
|6.||Went, Gregory T: 8 articles (05/2015 - 09/2008)|
|7.||Pinto, Lawrence H: 8 articles (04/2013 - 06/2006)|
|8.||Webster, Robert G: 8 articles (08/2010 - 02/2002)|
|9.||Nguyen, Jack T: 7 articles (02/2014 - 09/2008)|
|10.||Sova, Petr: 7 articles (10/2007 - 01/2004)|
|1.||Human Influenza (Influenza)
10/01/1996 - "In this epidemic, the combination of amantadine and vaccine was most effective in reducing the rate of influenza-associated sequelae. "
01/01/1994 - "In conclusion, rapid identification of the outbreak and prompt administration of amantadine hydrochloride prophylactically appears to be safe and effective in preventing further spread of influenza A."
10/01/1987 - "Compared with placebo, 100 mg of amantadine significantly reduced the frequency of illness (9 of 22 versus 2 of 22 volunteers, P less than 0.04) and provided 78% protection against influenza illness. "
09/01/2003 - "Earlier recognition and faster resolution of influenza outbreaks, fewer outbreaks, reduced pressure on acute care, greater compliance with amantadine prophylaxis, and improved immunization rates in seniors and health care workers. "
05/15/2001 - "Amantadine was judged effective in controlling 76% of the influenza A outbreaks and was discontinued because of side effects in 3% of the residents. "
|2.||Chronic Hepatitis C
01/01/2004 - "In 1997, it was suggested that amantadine monotherapy could be used successfully to treat patients with chronic hepatitis C who had previously failed IFN alfa therapy, but ensuing studies could not support these findings. "
10/01/2000 - "In conclusion, combination therapy IFN-alpha plus amantadine is as effective as IFN-alpha monotherapy in previously untreated patients with chronic hepatitis C."
10/01/2000 - "Although the antiviral effects of amantadine sulphate (1-aminoadamantan sulphate) have not been characterized for the hepatitis C virus (HCV), previous pilot studies have suggested promising results in patients with chronic hepatitis C. "
04/01/1999 - "However, few studies about efficacy of amantadine in chronic hepatitis C are available with controversial results. "
06/01/2003 - "The antiviral efficacy of amantadine in patients with chronic hepatitis C is controversial. "
|3.||Parkinson Disease (Parkinson's Disease)
02/01/2001 - "Amantadine has been proved to be beneficial in Parkinson's disease. "
03/01/1988 - "The rapid efficacy of amantadine on akinesia and rigidity in Parkinson's disease is generally known. "
01/01/2012 - "Open-label studies have suggested that intravenous (IV) amantadine is effective against FOG resistant to dopaminergic therapy in Parkinson's disease (PD). "
07/01/2015 - "Amantadine hydrochloride is an antiviral agent that is also effective in the treatment of Parkinson's disease. "
11/01/2001 - "The antiviral drug amantadine, that is effective in idiopathic Parkinson's disease (PD), may affect the composition and function of peripheral blood lymphocytes. "
09/21/2008 - "Finally, using our models we estimated that the maximum efficacy of amantadine in blocking viral infection is approximately 74%, and showed that this low maximum efficacy is likely due to the rapid development of drug resistance."
07/01/1980 - "These findings demonstrate that amantadine significantly inhibits the replication of dengue viruses in vitro and indicate a need to determine the efficacy of this drug against dengue virus infections in vivo."
12/01/2000 - "[Therapeutic efficacy of amantadine hydrochloride in patients with epidemic influenza A virus infection]."
11/01/2000 - "Recent preliminary data have suggested that amantadine (AMA) is effective against HCV infection. "
05/01/1980 - "During a study of efficacy of amantadine prophylaxis of influenza A virus infection in young adults, gross and subtle side effects were monitored. "
07/30/2007 - "The only currently available drug with an evidence-based recommendation on efficacy for dyskinesia is amantadine. "
02/01/2001 - "After 15 days with amantadine treatment all patients improved with an average 38% reduction in dyskinesias (p<0.001). "
03/01/2013 - "This study resolves 2 major issues useful for future testing of new antidyskinesia treatments: among tested scales, the UDysRS, having both subjective and objective dyskinesia ratings, is superior for detecting treatment effects; and the magnitude of the UDysRS effect size from amantadine sets a clear standard for comparison for new agents."
07/01/2012 - "This meta-analysis provides an update on the clinical trials and confirms the short-term benefits of amantadine therapy in the treatment of dyskinesia. "
01/01/2010 - "Results from the present study demonstrated that amantadine exhibited efficacious effects against dyskinesias in 60-70% of patients. "
|4.||Levodopa (L Dopa)
|8.||Antiviral Agents (Antivirals)
|9.||Interferon-alpha (Interferon Alfa)
|2.||Drug Therapy (Chemotherapy)
|3.||Home Nursing (Nursing, Home)