Amantadine (Aman)

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1444 relevant articles (182 outcomes, 207 trials/studies) found for this Drug

Description: An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.

Also Known As:

Aman; Symmetrel; tregor; Symadine; 1-Aminoadamantane; AbZ Brand of Amantadine Hydrochloride; Adamantylamine; Adekin; Aliud Brand of Amantadine Sulfate; Alliance Brand of Amantadine Hydrochloride; Amanta; Amanta-HCI-AZU; Amanta-Sulfate-AZU; Amantadin AL; Amantadin AZU; Amantadin Stada; Amantadin-neuraxpharm; Amantadin-ratiopharm; Amantadina Juventus; Amantadina Llorente; Amantadine Hydrochloride; Amantadine Sulfate; Amixx; Azupharma Brand of Amantadine Hydrochloride; Azupharma Brand of Amantadine Sulfate; Cerebramed; Ciba-Geigy Brand of Amantadine Hydrochloride; Desitin Brand of Amantadine Hydrochloride; Du Pont Brand of Amantadine Hydrochloride; Endantadine; Endo Brand of Amantadine Hydrochloride; Gen-Amantadine; Genpharm Brand of Amantadine Hydrochloride; Hexal Brand of Amantadine Sulfate; Hormosan Brand of Amantadine Sulfate; Infecto-Flu; Infectopharm Brand of Amantadine Hydrochloride; Infex; Juventus Brand of Amantadine Hydrochloride; Krewel Brand of Amantadine Hydrochloride; Llorente Brand of Amantadine Hydrochloride; Mantadix; Merz Brand of Amantadine Sulfate; Midantan; Neuro Hexal Brand of Amantadine Sulfate; Novartis Brand of Amantadine Hydrochloride; Orion Brand of Amantadine Hydrochloride; PMS-Amantadine; Pharmascience Brand of Amantadine Hydrochloride; Solvay Brand of Amantadine Hydrochloride; Stada Brand of Amantadine Hydrochloride; Stada Brand of Amantadine Sulfate; Thiemann Brand of Amantadine Hydrochloride; Viregyt; Wiregyt; neuraxpharm Brand of Amantadine Sulfate; ratiopharm Brand of Amantadine Hydrochloride; 1 Aminoadamantane; AL, Amantadin; AZU, Amantadin; Amanta HCI AZU; Amanta Sulfate AZU; AmantaHCIAZU; AmantaSulfateAZU; Amantadin neuraxpharm; Amantadin ratiopharm; Amantadinneuraxpharm; Amantadinratiopharm; Ciba Geigy Brand of Amantadine Hydrochloride; Gen Amantadine; GenAmantadine; Hydrochloride, Amantadine; Infecto Flu; InfectoFlu; Juventus, Amantadina; Llorente, Amantadina; PMS Amantadine; PMSAmantadine; Stada, Amantadin; Sulfate, Amantadine; Tricyclo(3.3.1.13,7)decan-1-amine

Relationship Network

Drug Context: Research Results

Experts

1.	Rivetti, D: 5 articles (01/2006 - 01/2000)
2.	Demicheli, V: 5 articles (01/2006 - 01/2000)
3.	Saito, Reiko: 4 articles (02/2008 - 09/2006)
4.	Li, Danjuan: 4 articles (02/2008 - 09/2006)
5.	Suzuki, Hiroshi: 4 articles (02/2008 - 09/2006)
6.	Sova, Petr: 4 articles (07/2006 - 01/2004)
7.	Kozubík, Alois: 4 articles (07/2006 - 01/2004)
8.	Kroutil, Ales: 4 articles (07/2006 - 01/2004)
9.	Deeks, J J: 4 articles (01/2004 - 01/2000)
10.	Berg, T: 4 articles (10/2003 - 10/2000)

Related Diseases

1.	Human Influenza (Influenza) 10/01/1996 - "CONCLUSION: In this epidemic, the combination of amantadine and vaccine was most effective in reducing the rate of influenza-associated sequelae" 01/01/1994 - "In conclusion, rapid identification of the outbreak and prompt administration of amantadine hydrochloride prophylactically appears to be safe and effective in preventing further spread of influenza A." 10/01/1987 - "Compared with placebo, 100 mg of amantadine significantly reduced the frequency of illness (9 of 22 versus 2 of 22 volunteers, P less than 0.04) and provided 78% protection against influenza illness" 09/01/2003 - "OUTCOMES: Earlier recognition and faster resolution of influenza outbreaks, fewer outbreaks, reduced pressure on acute care, greater compliance with amantadine prophylaxis, and improved immunization rates in seniors and health care workers" 05/15/2001 - "Amantadine was judged effective in controlling 76% of the influenza A outbreaks and was discontinued because of side effects in 3% of the residents" Order ALL the reference details at left...
2.	Chronic Hepatitis C 01/01/2004 - "In 1997, it was suggested that amantadine monotherapy could be used successfully to treat patients with chronic hepatitis C who had previously failed IFN alfa therapy, but ensuing studies could not support these findings" 10/01/2000 - "In conclusion, combination therapy IFN-alpha plus amantadine is as effective as IFN-alpha monotherapy in previously untreated patients with chronic hepatitis C." 10/01/2000 - "Although the antiviral effects of amantadine sulphate (1-aminoadamantan sulphate) have not been characterized for the hepatitis C virus (HCV), previous pilot studies have suggested promising results in patients with chronic hepatitis C" 04/01/1999 - "However, few studies about efficacy of amantadine in chronic hepatitis C are available with controversial results" 06/01/2003 - "The antiviral efficacy of amantadine in patients with chronic hepatitis C is controversial" Order ALL the reference details at left...
3.	Infection 09/21/2008 - "Finally, using our models we estimated that the maximum efficacy of amantadine in blocking viral infection is approximately 74%, and showed that this low maximum efficacy is likely due to the rapid development of drug resistance." 07/01/1980 - "These findings demonstrate that amantadine significantly inhibits the replication of dengue viruses in vitro and indicate a need to determine the efficacy of this drug against dengue virus infections in vivo." 12/01/2000 - "Therapeutic efficacy of amantadine hydrochloride in patients with epidemic influenza A virus infection]" 11/01/2000 - "Recent preliminary data have suggested that amantadine (AMA) is effective against HCV infection" 05/01/1980 - "During a study of efficacy of amantadine prophylaxis of influenza A virus infection in young adults, gross and subtle side effects were monitored" Order ALL the reference details at left...
4.	Parkinson Disease (Parkinson's Disease) 02/01/2001 - "Amantadine has been proved to be beneficial in Parkinson's disease" 03/01/1988 - "The rapid efficacy of amantadine on akinesia and rigidity in Parkinson's disease is generally known" 11/01/2001 - "The antiviral drug amantadine, that is effective in idiopathic Parkinson's disease (PD), may affect the composition and function of peripheral blood lymphocytes" 08/01/1976 - "Amantadine is a putative dopaminergic compound known to be therapeutically effective in idiopathic and postencephalitic Parkinson's disease" 07/01/1975 - "Amantadine appears effective in the long-term treatment of some patients with Parkinson's disease." Order ALL the reference details at left...
5.	Dyskinesias (Dyskinesia) 07/30/2007 - "The only currently available drug with an evidence-based recommendation on efficacy for dyskinesia is amantadine" 02/01/2001 - "After 15 days with amantadine treatment all patients improved with an average 38% reduction in dyskinesias (p<0.001)" 05/01/2001 - "Intravenous amantadine improves levadopa-induced dyskinesias: an acute double-blind placebo-controlled study." 04/11/2006 - "3. Amantadine may be considered to reduce dyskinesia (Level C)" 02/01/2006 - "Patients were scored using the dyskinesia scale and started treatment with 400 mg amantadine (po) for 4 days within the first postoperative week with no effect on dyskinesia score or its phenomenology" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Rimantadine
2.	Ribavirin (Virazole)
3.	Interferons
4.	Levodopa (L Dopa)
5.	Antiviral Agents (Antivirals)
6.	Interferon-alpha (Interferon Alfa)
7.	N-Methylaspartate (NMDA)
8.	Oseltamivir (Tamiflu)
9.	Zanamivir (Relenza)
10.	Dopamine (Intropin)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Drug Therapy (Chemotherapy)
3.	Home Nursing (Nursing, Home)
4.	Transplants (Transplant)
5.	Chemoprevention

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