alpha-Glucosidases (Acid Maltase)

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868 relevant articles (39 outcomes, 73 trials/studies) found for this Bio-Agent

Description: Enzymes that catalyze the exohydrolysis of 1,4-alpha-glucosidic linkages with release of alpha-glucose. Deficiency of alpha-1,4-glucosidase may cause GLYCOGEN STORAGE DISEASE TYPE II.

Also Known As:

Acid Maltase; Maltases; Maltase-Glucoamylase; Neutral Maltase; Neutral alpha-Glucosidase; alpha-Glucosidase; Lysosomal alpha Glucosidase; Maltase Glucoamylase; Neutral alpha Glucosidase; alpha Glucosidase; alpha Glucosidases; alpha-Glucosidase, Lysosomal; alpha-Glucosidase, Neutral; Lysosomal alpha-Glucosidase; alpha-D-Glucoside glucohydrolases

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Raben, N: 4 articles (08/2008 - 10/2000)
2.	Reuser, Arnold J J: 4 articles (01/2007 - 01/2004)
3.	Kroos, Marian A: 4 articles (01/2007 - 01/2004)
4.	Keutzer, Joan: 3 articles (10/2008 - 05/2006)
5.	Bali, Deeksha: 3 articles (04/2007 - 05/2006)
6.	Bembi, Bruno: 3 articles (03/2007 - 09/2003)
7.	Raben, Nina: 3 articles (01/2007 - 03/2002)
8.	Bird, Andrew: 3 articles (12/2006 - 04/2003)
9.	Sun, Baodong: 3 articles (12/2006 - 04/2003)
10.	Koeberl, Dwight D: 3 articles (12/2006 - 04/2003)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 06/01/1994 - "OBJECTIVE--To compare the different therapeutic principles of alpha-glucosidase inhibitors and sulphonylureas as first-line treatment in non-insulin-dependent diabetes mellitus (NIDDM) patients with dietary failure. " 10/01/1997 - "OBJECTIVE: The purpose of the study was to examine the relationship between gastric emptying and the efficacy of an alpha-glucosidase inhibitor in NIDDM patients. " 12/01/1998 - "The purpose of this study was to evaluate a long-term effect of alpha-glucosidase inhibitor treatment with ordinary meals in late dumping patients with NIDDM because administration of alpha-glucosidase inhibitor is only ethically allowed for diabetic patients in Japan. " 08/01/1994 - "Two rat models for non-insulin-dependent diabetes mellitus (NIDDM) have been used in our laboratory to study the effects of alpha-glucosidase inhibitors. " 01/01/2005 - "OBJECTIVES: To assess the effects of alpha-glucosidase inhibitors s in patients with type 2 diabetes mellitus. " Order ALL the reference details at left...
2.	Glycogen Storage Disease Type II (Pompe's Disease) 12/01/2006 - "Enhanced efficacy of an AAV vector encoding chimeric, highly secreted acid alpha-glucosidase in glycogen storage disease type II." 09/01/2000 - "However, individuals with Pompe disease showed a marked decrease in acid alpha-glucosidase protein in both plasma and whole blood compared with unaffected controls. " 06/01/2009 - "Glycoengineered acid alpha-glucosidase with improved efficacy at correcting the metabolic aberrations and motor function deficits in a mouse model of Pompe disease." 01/01/2005 - "Impact of humoral immune response on distribution and efficacy of recombinant adeno-associated virus-derived acid alpha-glucosidase in a model of glycogen storage disease type II." 04/01/1995 - "Leaky splicing mutation in the acid maltase gene is associated with delayed onset of glycogenosis type II." Order ALL the reference details at left...
3.	Hyperglycemia 07/01/2002 - "These results suggest that the extract from ezoishige has potent alpha-glucosidase inhibitors and would be effective for suppressing postprandial hyperglycemia." 05/01/2007 - "This study shows that compared to alpha-glucosidase inhibitors, DPP-IV inhibitors may have more consistent efficacy to reduce postprandial hyperglycemia, independent of the types of carbohydrate contained in a meal, and that the combination of a DPP-IV inhibitor and an alpha-glucosidase inhibitor is expected to be a promising option for lowering postprandial hyperglycemia." 10/01/2003 - "This study examined the alpha-glucosidase inhibitory effects of hyssop extracts on intestinal carbohydrate absorption in rat everted gut sac and carbohydrate-loaded hyperglycemia in mice. " 10/01/2009 - "flowers on alpha-glucosidase activity and postprandial hyperglycemia in normal and diabetic rats." 05/01/2008 - "We propose that a more physiologically relevant explanation lies in the phenolic-linked antioxidant activity and alpha-glucosidase inhibitory potential of eggplant which could reduce hyperglycemia-induced pathogenesis. " Order ALL the reference details at left...
4.	Diabetes Mellitus 10/01/2009 - "Finding effective mammalian alpha-glucosidase inhibitors from natural sources can be beneficial in the prevention and treatment of diabetes mellitus. " 08/01/2009 - "Inhibitors of alpha glucosidase have potential use in the treatment of diabetes mellitus. " 11/01/2008 - "elliptica have potential as natural nutraceuticals to prevent diabetes mellitus because of their high alpha-glucosidase inhibitory activity." 08/01/2001 - "Thus, the alpha-glucosidase inhibitory TE demonstrated an antihyperglycemic effect and may prove useful for improving glycemic control in subjects suffering from borderline and type-2 diabetes mellitus." 11/01/2000 - "CONCLUSIONS: We recommend serial evaluation for complications of GSD III, and propose that an alpha-glucosidase inhibitor may be a favourable drug in treating diabetes mellitus secondary to GSD III." Order ALL the reference details at left...
5.	Hypertension (High Blood Pressure) 01/01/2006 - "This enhanced functionality in terms of high alpha -glucosidase and alpha -amylase inhibitory activities indicate the potential for diabetes management, and high ACE-I inhibitory activity indicates the potential for hypertension management." 01/01/2006 - "Water soluble cranberry-based phytochemical combinations with oregano, rosemary, and Rhodiola rosea were evaluated for total phenolic content, related antioxidant activity and inhibition of diabetes management-related alpha -glucosidase, pancreatic alpha-amylase inhibition, and hypertension-related ACE-I inhibitory activities. " 01/01/2010 - "Strawberry cultivars with combined inhibitory potential against alpha-glucosidase and ACE and with moderate or low alpha-amylase inhibitory potential could be targeted for potential management of hyperglycemia-linked type 2 diabetes and related complication of hypertension." 06/25/2008 - "Fruits of seven fully ripened strawberry cultivars grown in Brazil (Dover, Camp Dover, Camarosa, Sweet Charlie, Toyonoka, Oso Grande, and Piedade) were evaluated for total phenolics, antioxidant activity based on DPPH radical scavenging assay, and functionality such as inhibition of alpha-amylase, alpha-glucosidase, and angiotensin I-converting enzyme (ACE) relevant for potentially managing hyperglycemia and hypertension. " 01/01/2005 - "Recently, STOP-NIDDM trial revealed that acarbose (Glucobay), an alpha-glucosidase inhibitor, improved postprandial hyperglycemia and subsequently reduced the risk of development of type 2 diabetes and newly diagnosed hypertension in patients with impaired glucose tolerance. " Order ALL the reference details at left...

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Related Therapies and Procedures

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