|1.||Cao, Lin: 1 article (01/2010)|
|2.||Zhou, Jieyun: 1 article (01/2010)|
|3.||Gui, Youlun: 1 article (01/2010)|
|4.||Lu, Yingying: 1 article (01/2010)|
|5.||Xie, Shuwu: 1 article (01/2010)|
|6.||Ma, Li: 1 article (01/2010)|
|7.||Zhu, Yan: 1 article (01/2010)|
|8.||Qian, Guoqing: 1 article (03/2008)|
|9.||Ling, Xiao: 1 article (03/2008)|
|10.||et al,: 1 article (03/2008)|
01/01/1974 - " U-5897 induced temporary sterility as demonstrated by blocked transport of spermatozoa, and spermatogenic cells eliminated from the spermatogenic epithelium which became blocked in the caudal part of the epididymis. "
01/01/1983 - " High doses of alpha-chlorohydrin can be neurotoxic, nephrotoxic, and in rats, leads to prolonged or permanent infertility. "
01/01/1983 - "High doses of alpha-chlorohydrin can be neurotoxic, nephrotoxic and, in rats, lead to prolonged or permanent infertility. "
12/01/1981 - "Daily administration of 9 mg/kg alpha-chlorohydrin for 7--14 days and 24 mg/kg 6CDG for 14--21 days induced sterility in male rats and imparied the capacity of the cauda epididymal spermatozoa to initiate motility. "
05/01/1979 - "When rats were injected with the derivatives at a dose equivalent to 5 mg/kg of alpha-chlorohydrin on a molar basis, the phosphorylated and amino acid derivatives produced complete infertility within 7 days; however, there were some signs of toxicity. "
|2.||Body Weight (Weight, Body)
07/01/1986 - "The present study was undertaken to determine the effects of alpha-chlorohydrin at a dosage of 50, 100 or 150 mg/kg body weight and were killed 2 or 10 days later. "
11/01/1995 - "alpha-Chlorohydrin (ACH) was administered daily for 4 days to male hamsters at 0, 33, 49, 66, and 83 mg/kg body weight. "
12/01/1979 - "Effect of single oral dose (90 mg/kg body weight), multiple doses (90 mg/kg body weight for 7 days) or even higher doses (180-300 mg/kg body weight) of alpha-chlorohydrin on the testis-epididymis complex of dog, rat, cryptorchid rat, hedgehog, domestic fowl, lizard, frog, and toad has been studied. "
06/01/1976 - "2, 5, 10 and 20 days) following injection of a lesion-forming dose (90 mg/kg body weight) of alpha-chlorohydrin and bilateral ligation of the vasa efferentia. "
05/01/1979 - "Administration of vasodilator, sodium nitrite (20 mg/kg body weight), 30 min before alpha-chlorohydrin treatment (90 mg/kg body weight) prevented the chlorohydrin-induced lesion in rat testis--epididymis complex. "
|3.||Wounds and Injuries (Trauma)
03/01/2008 - "(1) In Comparison with control groups, the mating index and male fertility index in male mice exposed to S-alpha-chlorohydrin for two months at any dose level were not changed; (2) There were no significant changes in cauda sperm count between treated and control groups, and no obvious histopathological injuries were observed in testes and epididymides of treated mice. "
08/01/1983 - "Reported similarities in the acute toxic effects of 1,2-dibromo-3-chloropropane (DBCP), 3-chloro-1,2-propaneoxide (epichlorohydrin, ECH), 3-chloro-1,2-propanediol (alphachlorohydrin, ACH), and oxalic acid (OA) have been suggested as presumptive evidence that the metabolism of DBCP to OA, via ECH and ACH, is the cause of the resulting injuries to the kidney and, perhaps, to the epididymis and testis. "
07/01/1977 - "2. Chronic administration of alpha-chlorohydrin alone (140 mg/day for 40 days) caused testicular lesion resulting in a massive atrophy of the spermatogenic elements. "
03/01/1975 - "A single high dose of alpha-chlorohydrin increased the total cholesterol/g of wet testis tissue which could be correlated with the testicular atrophy. "
|5.||Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
|2.||Oxalic Acid (Acid, Oxalic)