|2.||Hypercalcemia (Milk Alkali Syndrome)
|3.||Hypertension (High Blood Pressure)
|5.||Body Weight (Weight, Body)
|1.||Lin, Shih-Hua: 11 articles (03/2015 - 05/2002)|
|2.||Tajima, Toshihiro: 5 articles (02/2012 - 02/2002)|
|3.||Goss, Greg G: 4 articles (04/2015 - 03/2002)|
|4.||Yang, Sung-Sen: 4 articles (03/2015 - 05/2007)|
|5.||Hsu, Yu-Juei: 4 articles (03/2015 - 02/2004)|
|6.||Faisy, Christophe: 4 articles (01/2014 - 05/2010)|
|7.||Wakabayashi, Ichiro: 4 articles (11/2006 - 05/2003)|
|8.||Zuccarello, M: 4 articles (12/2000 - 08/2000)|
|9.||Rapoport, R M: 4 articles (12/2000 - 08/2000)|
|10.||Chau, Tom: 3 articles (03/2015 - 10/2003)|
12/01/2010 - "She responded well to the treatment and the calcium concentration, renal function and metabolic alkalosis were normalized. "
01/01/2015 - "The plasma anion gap increases in non-hypoproteinemic metabolic alkalosis due to an increased negative charge equivalent on albumin and the free ionized calcium (Ca(++)) content of plasma decreases. "
01/01/2014 - "This occurs through the effects of Alkalosis upon cerebral vasoconstriction and the amount of ionized calcium in the serum. "
09/01/2012 - "Further, the influence of alkalosis in reducing ionized calcium has been well known for a long time. "
03/01/2010 - "It inhibits coagulation by binding to ionized calcium and leads to metabolic alkalosis. "
|2.||Acetazolamide (Diamox)FDA LinkGeneric
09/01/1991 - "We conclude that in patients with metabolic alkalosis, once fluid and electrolyte abnormalities have been corrected, acetazolamide is an effective and safe form of therapy with a quick onset and long duration of action."
11/01/2014 - "Acetazolamide for the management of chronic metabolic alkalosis in neonates and infants."
10/01/1986 - "This study shows that administration of acetazolamide or HCl results in a dose-dependent decrease of plasma and tissue pH, and that both agents may be used as a logical and safe therapy during severe metabolic alkalosis in rats."
01/01/2015 - " severe metabolic alkalosis can be safely and successfully treated with acetazolamide."
01/01/2015 - "Treatment of metabolic alkalosis with acetazolamide was thus initiated and pH levels successfully lowered. "
02/01/1994 - "This case also shows that life-threatening alkalemia can be safely and effectively treated by defining and removing the causes of alkalosis and applying aggressive supportive therapy with fluid repletion and potassium and electrolyte replacement. "
02/01/1990 - "Studies were performed on previously nephrectomized dogs to examine roles of hormonal factors in plasma potassium alterations in acute alkalosis. "
10/01/1988 - "Studies were performed to investigate the role of concomitant chloride depletion in potassium-depletion alkalosis in the rat and the relationship between potassium depletion, plasma bicarbonate (PHCO3), and net acid excretion. "
07/01/1988 - "These studies suggest that the ability to excrete a base load remains intact despite potassium or chloride depletion or metabolic alkalosis. "
05/01/1955 - "Interrelationship of acute alkalosis and potassium metabolism: a clinical study."
|4.||Lactic AcidFDA LinkGeneric
12/01/2001 - "The supposition that accumulation of lactate may protect the brain of LS patients from alkalosis-related damage requires further study. "
03/01/1991 - "Rebound alkalosis and persistent lactate: multinuclear (1H, 13C, 31P) NMR spectroscopic studies in rats."
04/01/2012 - "There was a reduction in blood lactate and an increase in pH during the withdrawal phase, possibly because of an increase in fluid retention, plasma volume, and cellular alkalosis. "
01/01/2008 - "Augmented serum lactic acid combined with metabolic alkalosis: a case report."
02/01/2004 - "Such brain alkalosis may be detrimental to cell survival and may increase glycolytic rate in astrocytes leading to an increased production of lactate."
|5.||Sodium Bicarbonate (Baking Soda)FDA LinkGeneric
10/01/1990 - "The efficacy of sodium bicarbonate is presently debated, considering the risk to worsen hyperlactatemia and to induce hyperosmolarity or rebound alkalosis. "
08/15/2015 - "The present study demonstrates that outwardly-directed sodium bicarbonate cotransport via electrogenic sodium bicarbonate cotransporter 1 (NBCe1) mediates the major fraction of H(+) i regulation from cytosolic alkalosis in mouse cortical astrocytes. "
05/01/2005 - "Previous studies have shown that induced metabolic alkalosis, via sodium bicarbonate (NaHCO3) ingestion, can improve short-term, repeated-sprint ability. "
05/01/2004 - "The purpose of this study was to assess the effects of induced metabolic alkalosis, via sodium bicarbonate (NaHCO3) ingestion, on muscle metabolism and power output during repeated short-duration cycle sprints. "
07/01/1996 - "The purpose of the present study was to assess the effect of induced-metabolic alkalosis produced by administration of sodium bicarbonate on dyspneic sensation. "
|6.||Furosemide (Lasix)FDA LinkGeneric
04/01/1994 - "These studies demonstrate that Cl- repletion corrects chronic furosemide-induced metabolic alkalosis predominantly by a renal mechanism and that combined administration of K+ and Cl-, but not of Cl- alone, corrects the augmented H+ secretion in the distal tubule in this model of chronic alkalosis."
04/01/1994 - "The present studies used in vivo microperfusion micropuncture to investigate whether combined repletion of K+ and Cl- corrected the augmented H+ secretion in the distal tubule of rats with chronic furosemide-induced metabolic alkalosis. "
02/01/2002 - "It is known that furosemide causes a metabolic alkalosis. "
07/01/1999 - "Frusemide at both dosages induced a significant metabolic alkalosis associated with a decrease in plasma çhloride[ in both arterial and mixed venous blood. "
04/01/1998 - "Chronic metabolic alkalosis was induced with furosemide followed by minimum electrolyte diet and HCO3 drinking water. "
|7.||Epinephrine (Adrenaline)FDA LinkGeneric
05/01/2002 - "The purpose of this study was to determine the effects of alkalosis on epinephrine concentrations in response to a 90 s maximal exercise test. "
05/01/2002 - "The primary finding of this investigation was that orally-induced alkalosis does not significantly affect plasma epinephrine concentrations or performance following 90 s of maximal cycle exercise in untrained men."
05/01/2002 - "Effect of alkalosis on plasma epinephrine responses to high intensity cycle exercise in humans."
12/01/1993 - "In the first protocol, hemodynamic responses to epinephrine during pure metabolic acidemia or metabolic alkalosis were studied in eight lambs. "
04/01/1975 - "Most of metabolic actions of epinephrine and isoproterenal known to be mediated via the beta receptor were significantly reduced but not completely abolished during alkalosis. "
|8.||Parathyroid Hormone (Parathormone)IBA
08/01/1982 - "Parathyroid-hormone-induced metabolic alkalosis in dogs."
01/01/1980 - "Effect of metabolic acidosis and alkalosis on the renal response to parathyroid hormone infusion in normal man."
11/01/2012 - "He developed altered behavior and generalized weakness, and on investigation, hypercalcemia, hypokalemia, and metabolic alkalosis with low parathyroid hormone levels were detected. "
11/01/1965 - "Parathyroid hormone-secreting renal carcinoma associated with hypercalcemia and metabolic alkalosis."
09/01/2011 - "Laboratory analysis revealed hypocalcemia, hypokalemia, alkalosis with hypercalciuria, and low-normal parathormone (PTH) at first and elevated PTH at the second admission. "
02/27/2009 - "Alkalosis impairs the natriuretic response to diuretics, but the underlying mechanisms are unclear. "
01/01/1995 - "Diuretics-induced metabolic alkalosis decreased intensification of natriuresis and diuresis resultant from large-dose KCl treatment."
02/27/1989 - "A case of hypokalaemia and metabolic alkalosis precipitated by a self-composed slimming diet in a woman treated with diuretics is presented. "
05/01/1980 - "The findings raise the possibility that direct enhancement of renal H+ secretion may play a role in the metabolic alkalosis induced by some diuretics."
02/01/1956 - "Response to mercurial diuretics during alkalosis: a comparison of acute metabolic and chronic hypokalemic alkalosis in the dog."
|10.||Spironolactone (Aldactone)FDA LinkGeneric
02/01/1992 - "Long-term treatment with spironolactone controlled the hypertension and prevented hypokalemic alkalosis in this patient, without any deleterious effects on steroid biosynthesis. "
01/01/1980 - "The pressure fall induced by spironolactone was also associated with a persistent contraction in plasma volume (p less than 0.05) and a secondary hyperaldosteronism that was not accompanied by hypokalemic alkalosis. "
05/01/1977 - "Reversal of the hypertension and hypokalemic alkalosis occurred when spironolactone was administered. "
05/01/1977 - "Hypertension and hypokalemic alkalosis were corrected by spironolactone or a low sodium diet. "
12/01/1986 - "Treatment with spironolactone alone for 2 months corrected hypertension, hypokalemic alkalosis, and all laboratory and radiologic evidence of rickets and hyperparathyroidism, resulting in acceleration of growth rate. "
|1.||Renal Dialysis (Hemodialysis)
08/01/2009 - "Metabolic alkalosis was corrected and the patient's clinical condition was relieved with negative-bicarbonate hemodialysis. "
04/01/2001 - "The metabolic alkalosis improved with hemodialysis using a low-bicarbonate bath."
12/01/2011 - "Prolonged immobilization as a potential etiology of metabolic alkalosis in hemodialysis patients."
07/01/2011 - "Severe metabolic alkalosis in a hemodialysis patient."
01/01/2006 - "[Severe asymptomatic mixed alkalosis in a female patient during hemodialysis]."
03/01/2008 - "These effects on base excess were partly offset by a greater metabolic alkalosis in the transplant group caused by a marked effect of decreased albumin on base excess (5.8 +/-1.5 mmol/L). "
12/01/2003 - "The authors encountered a patient who had profound hypochloremic metabolic alkalosis after developing profuse diarrhea related to rejection of her small bowel transplant. "
04/01/1989 - "Prompt diagnosis and treatment are necessary for hypertension, hypokalemia, severe metabolic alkalosis, fever, altered mental status, oliguria, and signs of graft failure in liver transplant patients. "
11/01/1994 - "Sixteen and 28 h after graft reperfusion, when plasma DCA had been eliminated, plasma lactate and degree of metabolic alkalosis did not differ between groups. "
05/01/1999 - "It is consistent with, but does not prove, the concept that the graft liver responds to metabolic alkalosis by augmenting Ra urea, thus increasing HCO-3 consumption and moderating the severity of metabolic alkalosis produced elsewhere."
|3.||Mechanical Ventilators (Ventilator)
12/01/2009 - "Post-hypercapnic alkalosis is associated with ventilator dependence and increased ICU stay."
10/01/1989 - "Alkalosis produced by respirator hyperventilation increased the arterial pH from 7.41 +/- 0.03 to 7.60 +/- 0.03 (n = 8, p less than 0.01), with a fall in ED90 from 13 +/- 4 to 8 +/- 3 J (p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)"
05/01/1990 - "2. Artificial ventilation with room air at a fixed volume of 10 ml kg-1 successfully induced combinations of hypoxaemia, hypercarbia and acidosis at a ventilator rate of 37 strokes min-1 and of hyperoxaemia, hypocarbia and alkalosis at 160 strokes min-1. "
12/01/1999 - "Although extrapolation of data from normal piglets to infants and children with pulmonary hypertension must be done with caution, this study suggests that sustained alkalosis may be of limited efficacy in treating acute hypoxia-induced pulmonary hypertension and the risks of pulmonary hypertension must be considered when using ventilator strategies resulting in permissive hypercapnic acidosis."
09/01/1989 - "The studies were carried out in placebo control and metabolic alkalosis induced by oral administration of NaHCO3. "
06/01/1988 - "The studies were performed after oral administration of NaHCO3 (alkalosis) and CaCO3 (placebo). "
11/01/1984 - "The studies were carried out after oral administration of CaCO3 (control), NH4Cl (metabolic acidosis), and NaHCO3 (metabolic alkalosis). "
01/01/2004 - "Rates of ureagenesis were measured in eight healthy volunteers during control, chronic metabolic acidosis (induced by oral administration of CaCl2 3.2 mmol.kg body wt-1.day-1 for 11 days), and recovery as well as during bicarbonate infusion (200 mmol over 240 min; acute metabolic alkalosis). "
09/01/1981 - "1. Five males were studied on three occasions, after oral administration of CaCO3 (control), NH4Cl (acidosis) and NaHCO3 (alkalosis), in a dose of 0.3 g/kg, taken over a 3 h period at rest. "
07/01/1984 - "During 6 h of isocapnic metabolic alkalosis, produced by intravenous infusion of Na2CO3 solution, plasma [HCO3-] was increased by approximately 14 meq/l in both groups. "
10/01/1983 - "Similarly, metabolic alkalosis of renal origin, at least in part, occurred when PTH was administered by chronic continuous intravenous infusion (group II). "
09/01/1990 - "Acidosis or alkalosis was produced by intravenous infusion of 1 mol/L HCl or 1 mol/L NaHCO3 respectively, in animals artificially ventilated with room air. "
08/01/1981 - "We have measured the brain surface pH during 30 min of isocapnic metabolic acidosis or alkalosis induced by intravenous infusion of 0.2 N HCl or NaOH in anesthetized dogs. "
11/01/2011 - "IVT with equal amount of FFP and crystalloids is optimal for liver transplantation surgery because it prevents development of metabolic acidosis wich appears due to intravenous infusion large dose of crystalloids on the other had it prevent metabolic alkalosis at the end of the surgery because of considerable amount of FFP."