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Akinetic Mutism (Coma Vigil)

A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance. Bilateral FRONTAL LOBE dysfunction involving the anterior cingulate gyrus and related brain injuries are associated with this condition. This may result in impaired abilities to communicate and initiate motor activities. (From Adams et al., Principles of Neurology, 6th ed, p348; Fortschr Neurol Psychiatr 1995 Feb;63(2):59-67)
Also Known As:
Coma Vigil; Akinetic Autism; Coma Vigilans; Akinetic Mutisms; Autism, Akinetic; Vigil, Coma; Vigils, Coma; Mutism, Akinetic
Networked: 75 relevant articles (11 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Stroke (Strokes)
2. Neurologic Manifestations (Neurological Manifestations)
3. Movement Disorders (Movement Disorder)
4. Bruxism
5. Poisoning

Experts

1. Iwasaki, Yasushi: 4 articles (10/2015 - 01/2012)
2. Yoshida, Mari: 2 articles (10/2015 - 06/2014)
3. Kitamoto, Tetsuyuki: 2 articles (10/2015 - 06/2014)
4. Mimuro, Maya: 2 articles (10/2015 - 06/2014)
5. Mariën, Peter: 2 articles (10/2013 - 01/2013)
6. Verhoeven, Jo: 2 articles (10/2013 - 01/2013)
7. Akagi, Akio: 1 article (10/2015)
8. Caralt, M: 1 article (11/2014)
9. Lazaro, J: 1 article (11/2014)
10. Dopazo, C: 1 article (11/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Akinetic Mutism:
1. Bromocriptine (Parlodel)FDA LinkGeneric
2. Dopamine Agonists (Dopamine Agonist)IBA
3. zolpidem (Ambien)FDA LinkGeneric
4. BaclofenFDA LinkGeneric
5. Cyclosporine (Ciclosporin)FDA LinkGeneric
6. Trihexyphenidyl (Artane)FDA LinkGeneric
7. Levodopa (L Dopa)FDA LinkGeneric
8. GABA Agonists (GABA Receptor Agonists)IBA
9. Metoprolol (Lopressor)FDA LinkGeneric
10. Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric

Therapies and Procedures

1. Enteral Nutrition (Feeding, Tube)
2. Aftercare (After-Treatment)
3. Active Euthanasia
4. Transplants (Transplant)
5. Chemoprevention