|5.||B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
|1.||Kanegane, Hirokazu: 9 articles (01/2014 - 09/2002)|
|2.||Miyawaki, Toshio: 9 articles (03/2011 - 09/2002)|
|3.||Plebani, Alessandro: 7 articles (12/2010 - 03/2004)|
|4.||Cunningham-Rundles, Charlotte: 6 articles (08/2015 - 07/2006)|
|5.||Orange, Jordan S: 6 articles (08/2015 - 08/2003)|
|6.||Notarangelo, Luigi D: 6 articles (07/2008 - 03/2004)|
|7.||Oksenhendler, Eric: 4 articles (10/2014 - 05/2008)|
|8.||Sullivan, Kathleen E: 4 articles (01/2014 - 10/2007)|
|9.||Smith, C I Edvard: 4 articles (12/2013 - 02/2005)|
|10.||Aghamohammadi, Asghar: 4 articles (09/2012 - 03/2004)|
01/01/2014 - "Although the underlying cause of the primary hypogammaglobulinemia remains unclear, the patient's status improved under immunoglobulin replacement therapy. "
11/01/2009 - "The aim of this study was to review the clinical and laboratory records of patients with unclassified hypogammaglobulinemia and to evaluate whether these children experience changes in serum immunoglobulin concentrations during long-term followup and have an exact diagnosis in natural course of disease. "
05/01/2006 - "Prospective open-label study of pharmacokinetics, efficacy and safety of a new 10% liquid intravenous immunoglobulin in patients with hypo- or agammaglobulinemia."
09/01/1965 - "Immunoglobulin studies in six kindreds of patients with adult hypogammaglobulinemia."
12/01/2014 - "Intravenous immunoglobulin was approved by FDA (Food and Drug Administration) in USA in 1981 for the first time and was started to be primarily used in patients with immune deficiency with hypogammaglobulinemia. "
|2.||Immunoglobulin G (IgG)IBA
07/01/2005 - "Serum IgG levels between 300-500 mg/dl are sufficient for effective treatment of hypogammaglobulinemias. "
01/01/2012 - "Seven of the eight patients identified in our search demonstrated simultaneous improvement in AD and serum IgG levels within 2 years of initial presentation, suggesting a diagnosis of transient hypogammaglobulinemia. "
01/01/2015 - "This study has shown IgG protein fraction stability in bovine fresh frozen plasma collected for transfusion; therefore, bovine fresh frozen plasma seems to be suitable for the treatment of hypogammaglobulinemia (failure of passive transfer) in calves when stored for 12 months at -20°C."
09/01/1990 - "Few pigs had hypogammaglobulinemia, less than 3% of the study population had serum IgG concentrations less than 1 g/dl. "
09/01/2015 - "Excretional loss rather than deficient production of IgG was demonstrated to underlay hypogammaglobulinemia. "
|3.||Intravenous Immunoglobulins (IVIG)FDA Link
02/01/1987 - "This study showed equivalent efficacy of native IVIG as compared with reduced and alkylated IVIG during maintenance therapy for hypogammaglobulinemia."
06/01/2014 - "CVID patients have hypogammaglobulinemia, respond to IVIG and have a dysregulated antimicrobial peptide response to pathogenic bacteria in the upper respiratory tract. "
04/01/2013 - "Symptomatic hypogammaglobulinemia that prompted IVIG administration developed in 6.6% of patients. "
02/01/2013 - "These molecules were used in low doses, mimicking the recommended use of IVIg in the case of hypogammaglobulinemia in humans. "
01/01/2009 - "Laboratory parameters revealed hypogammaglobulinemia prompting IVIG administration. "
|4.||rituximab (Mabthera)FDA Link
06/01/2013 - "We report two patients with granulomatosis with polyangiitis in remission with rituximab maintenance therapy with sustained hypogammaglobulinemia. "
08/01/2015 - "Caution should be exercised when considering rituximab for patients with preexisting hypogammaglobulinemia."
01/01/2015 - "[Rituximab and hypogammaglobulinemia]."
05/01/2014 - "Complicated pathophysiology behind rituximab-induced persistent hypogammaglobulinemia."
11/01/2013 - "Use of immunosuppressive treatment did not show a statistical association with hypogammaglobulinemia, although two of the patients with hypogammaglobulinemia did receive rituximab. "
12/01/1998 - "Anemia, lymphopenia, hypogammaglobulinemia, profound anti-F1 cytotoxicity, and the loss of cytotoxic potential against third party alloantigen is seen in acute lethal GVH disease. "
08/01/1995 - "Acute lethal GVH disease is characterized by anemia, lymphopenia, hypogammaglobulinemia, profound anti-F1 cytotoxicity, and the loss of cytotoxic potential against third-party alloantigen. "
10/01/1993 - "Acute lethal GVH disease is characterized by anemia, lymphopenia, hypogammaglobulinemia, profound anti-F1 cytotoxicity, and the loss of cytotoxic potential against third-party alloantigen. "
01/01/1987 - "The availability of intravenous gamma globulin preparations that are safe and effective has revolutionized replacement therapy in those patients suffering primary or secondary hypogammaglobulinemia. "
08/01/1964 - "HYPOGAMMAGLOBULINEMIA; IODINATED GAMMA GLOBULIN STUDIES."
11/01/2002 - "He was diagnosed with agammaglobulinemia at the age of 6 years and had been receiving gamma-globulin supplementation since then. "
11/11/1995 - "[The safety of treatment with intravenous gamma-globulin in patients with primary hypogammaglobulinemias]."
05/01/1992 - "[Side effects of administration of gamma globulin preparations in patients with primary agammaglobulinemia]."
|7.||Inosine Triphosphate (ITP)IBA
10/01/2014 - "We retrospectively analyzed 189 ITP patients receiving RTX in 3 referral centers in France and conducted a systematic review of 32 studies (results published 2001-2014) reporting the use of RTX for ITP, particularly searching for symptomatic secondary hypogammaglobulinemia. "
10/01/2014 - "Finally, we found 4 case reports of ITP and symptomatic hypogammaglobulinemia possibly related to RTX according to the authors. "
10/01/2014 - "We also searched for case reports of hypogammaglobulinemia after RTX initiation for ITP. "
04/01/2005 - "A retrospective review of 46 courses of IGIV therapy showed that the therapy was most often used for hematologic, neurologic, and immunologic indications, and the most common diagnoses for which it was used were hypogammaglobulinemia, ITP, and CIDP. "
04/01/2005 - "The three main indications for IGIV therapy were hypogammaglobulinemia, idiopathic thrombocytopenic purpura (ITP), and chronic inflammatory demyelinating polyneuropathy (CIDP). "
|8.||Immunoglobulin M (IgM)IBA
10/01/2012 - "The X-linked hyper-IgM (XHIM) syndrome is a rare form of primary immunodeficiency disorder characterized by hypogammaglobulinemia and impaired cell immunity. "
03/01/2012 - "Protective effect of IgM against colonization of the respiratory tract by nontypeable Haemophilus influenzae in patients with hypogammaglobulinemia."
12/01/2010 - "The set of criteria including low IgM scores, impaired antibody response and low B cell counts provided a high predictive value in detecting those with persistent hypogammaglobulinemia."
03/01/2010 - "Diagnostic cytology and morphometry of Penicillium marneffei in the sputum of a hypogammaglobulinemia with hyper-IgM patient."
11/01/2009 - "Hypogammaglobulinemia with hyper-IgM (HIGM) was recorded in 5 patients, and 3 patients developed panhypogammaglobulinemia. "
|9.||Growth Hormone (Somatotropin)IBA
12/01/2005 - "An additional case of X-linked hypogammaglobulinemia with isolated growth hormone deficiency and an unaffected male have been born to a female carrier in the family, allowing improved disease locus mapping. "
06/26/1980 - "We undertook clinical, immunologic, and endocrinologic studies of a family in which two brothers and their two maternal uncles had a similar disorder characterized by hypogammaglobulinemia and isolated growth hormone deficiency. "
05/28/2006 - "[X-linked hypogammaglobulinemia with growth hormone deficiency]."
03/01/2006 - "We report a first case with X-linked lymphoproliferative disease associated with hypogammaglobulinemia and growth-hormone deficiency, which was confirmed by SAP gene mutation. "
03/01/2006 - "X-linked lymphoproliferative disease associated with hypogammaglobulinemia and growth-hormone deficiency."
|10.||Carbamazepine (Tegretol)FDA LinkGeneric
04/01/2012 - "Carbamazepine-induced hypogammaglobulinemia."
01/01/2010 - "We report a case of hypogammaglobulinemia associated with aplasia of B lymphocytes after carbamazepine treatment. "
01/01/2010 - "B cell aplasia and hypogammaglobulinemia after carbamazepine treatment."
04/01/2012 - "Previous reports describe severe infection after carbamazepine-induced hypogammaglobulinemia. "
01/01/2012 - "In this report we describe the first pediatric patient who developed a severe interstitial pneumonitis and a pan-hypogammaglobulinemia 2 months after starting carbamazepine. "
09/01/1999 - "In the case of agammaglobulinemia effusion and swelling will decrease soon after treatment with intravenous gammaglobulin."
01/15/2002 - "Patient 2 is in complete remission 16 months after treatment, but patient 3 developed a hypogammaglobulinemia and died of invasive aspergillosis after 6 months. "
05/01/2008 - "Profound hypogammaglobulinemia 7 years after treatment for indolent lymphoma."
12/15/1994 - "Hepatitis C infection in patients with primary hypogammaglobulinemia after treatment with contaminated immune globulin."
09/01/1989 - " The literature indicates that hypogammaglobulinemia, immunocompromise, postpartum or postabortion fever, and urinary tract manipulation are the risk factors most commonly associated with mycoplasmal septic arthritis. "
|2.||Transplantation (Transplant Recipients)
05/01/2013 - "The aim of this study is to describe the phenomenon of hypogammaglobulinemia (HGG) in the immediate post-transplantation period among children undergoing LTx. "
03/22/1957 - "Transplantation studies in patients with agammaglobulinemia."
11/01/2014 - "Hypogammaglobulinemia was diagnosed at median of 5.6 months (range: 0-291.8 months) post-transplantation. "
11/01/2014 - "Severe hypogammaglobulinemia (IgG < 400 mg/dL) has adverse impact on mortality during the first year post-transplantation. "
07/01/2013 - "Hypogammaglobulinemia (HGG) has been associated with an increased risk of infectious complications in lung transplant recipients, but its effect specifically on community-acquired respiratory viruses (CARVs) remains unknown. "
|3.||Drug Therapy (Chemotherapy)
10/01/2007 - "At the study institution, hypogammaglobulinemia was found most often as a secondary immune deficiency due to chemotherapy or from complex cardiac anomalies. "
06/01/2011 - " is concluded that hypogammaglobulinemia is a common complication in chemotherapy using RTX combined with CHOP, the decreased level of Ig is recovered to normal level about 1 year after stop of treatment, the decrease of Ig in some cases can last even for over 2 years."
04/01/2002 - "Patient characteristics included: median age 67 years (range, 40-83), median 3 chemotherapy treatments (range, 1-8), and hypogammaglobulinemia in 73% of patients. "
01/01/1984 - "The hypogammaglobulinemia also remitted after chemotherapy for Hodgkin's lymphoma. "
01/09/2006 - "None of the following factors could predict a poor antibody response: gender, disease activity or aggressiveness in hematological malignancies, previous radiotherapy and/or chemotherapy, time between splenectomy and pneumococcal vaccination, time between chemotherapy/radiotherapy and study pneumococcal vaccination (1 year), or the presence of hypogammaglobulinemia. "
01/01/2002 - "Thus, we describe the case of a patient with Good's syndrome associated with independent humoral immunodeficiency in whom the effect of thymectomy for hypogammaglobulinemia was negative. "
12/01/1977 - "Hypogammaglobulinemia was detected two years after thymectomy. "
01/01/2009 - "We discuss a 46-year-old woman with thymoma and simultaneous PRCA and hypogammaglobulinemia who achieved complete remission from PRCA after perioperative steroid administration and extended thymectomy, and review the literature."
01/01/2002 - "In this respect, thymectomy was only beneficial when the thymoma proliferated and seemed to be more threatening than the hypogammaglobulinemia for the patient."
06/01/1999 - "[A case of pure red cell aplasia with hypogammaglobulinemia appearing after thymo-thymectomy]."