|2.||Septic Shock (Toxic Shock Syndrome)
|3.||Hypopituitarism (Sheehan's Syndrome)
|5.||Systemic Lupus Erythematosus (Libman-Sacks Disease)
|1.||Arlt, Wiebke: 15 articles (10/2014 - 09/2002)|
|2.||Huebner, Angela: 13 articles (09/2015 - 02/2003)|
|3.||Annane, Djillali: 13 articles (05/2013 - 01/2002)|
|4.||Koehler, Katrin: 10 articles (07/2015 - 03/2006)|
|5.||Allolio, Bruno: 10 articles (01/2014 - 09/2002)|
|6.||Hahner, Stefanie: 8 articles (01/2015 - 11/2005)|
|7.||Sprung, Charles L: 8 articles (02/2013 - 10/2002)|
|8.||Ross, Richard J: 7 articles (04/2015 - 09/2004)|
|9.||Marik, Paul E: 7 articles (10/2011 - 06/2002)|
|10.||Huebner, A: 7 articles (08/2010 - 11/2000)|
|1.||Hydrocortisone (Cortisol)FDA LinkGeneric
02/01/2015 - "Two parameters were found to be significant predictors of remission after the first treatment: age at disease diagnosis and the development of adrenal insufficiency (cortisol <3 μg/dl) in the immediate post-operative state. "
10/01/2012 - "Adjunctive therapy with hydrocortisone is sometimes beneficial in the setting of catecholamine resistance and/or adrenal insufficiency. "
06/01/2005 - "Although all cured CD patients (Group I) presented serum cortisol level lower than 55 nmol/l until 72 h after surgery, none had significant complications related to adrenal insufficiency. "
06/01/2007 - "This study showed that a 60-minute cortisol value during SST was reliable enough in identifying normal subjects for excluding adrenal insufficiency, and was equally effective in identifying abnormal cases, as compared to values at both 30 and 60 minutes. "
07/01/2013 - "Salivary cortisol is a useful tool to assess endogenous cortisol excess or adrenal insufficiency and to evaluate stable CD in remission."
09/01/2001 - "The exact physiological role of DHEA remains unknown but DHEA supplementation has recently been proven beneficial in typical deficient states like adrenal insufficiency or major depressive illlnesses. "
09/01/2004 - "Our study confirms that DHEA may be beneficial for female patients with hypoadrenalism, mainly in restoring androgen levels. "
04/01/2009 - "The efficacy of oral dehydroepiandrosterone (DHEA) in the treatment of atrichia pubis and psychological distress in young females with central adrenal insufficiency is unknown. "
11/01/2010 - "To date, studies of dehydroepiandrosterone therapy in women with adrenal insufficiency suggest that they are the most likely group to gain health benefits from dehydroepiandrosterone replacement therapy. "
10/01/2009 - "Eligible trials randomly assigned women with primary or secondary adrenal insufficiency to either DHEA or control and measured the effect of treatment on HRQOL. "
|3.||Adrenocorticotropic Hormone (ACTH)FDA Link
10/01/1999 - "The efficacy of the standard high dose ACTH stimulation test (HDT), using a pharmacological 250-microg dose of synthetic ACTH-(1-24), in the diagnosis of central hypoadrenalism is controversial. "
05/01/2013 - "Intramuscular ACTH test using Acton Prolongatum is effective in evaluation of adrenal function in all suspected cases of primary or secondary adrenal insufficiency. "
05/01/2013 - "First group called validation group, was studied for validation of intramuscular ACTH test and second group called study group, was evaluated for efficacy of intramuscular ACTH test to detect adrenal insufficiency. "
01/01/2013 - "The low-dose ACTH stimulation test is increasingly used for evaluation of secondary adrenal insufficiency as several studies performed in adults have demonstrated high sensitivity and specificity when compared to the ITT. "
10/01/2012 - "The purposes of the study were to determine the incidence of adrenal insufficiency (AI) using several published techniques, compare the response rates using a low-dose (LD) corticotropin (ACTH) stimulation test vs a standard dose (SD), and identify the technique that is most closely related to vasopressor use. "
01/01/2015 - "With few and sometimes conflicting data and study methodology the prevalence of adrenal insufficiency secondary to locally applied glucocorticoids is not clear. "
12/17/2010 - "In this study, we analyzed the possible roles of endogenous glucocorticoids in hematopoiesis and lymphopoiesis in MC2R(-/-) and CRH(-/-) mice as models of chronic adrenal insufficiency. "
05/01/2009 - "Randomized controlled trials are needed to evaluate the efficacy and safety of glucocorticoids for the treatment of cardiovascular insufficiency due to relative adrenal insufficiency in ill preterm and term newborn infants."
06/01/2015 - "Adrenal Insufficiency in Australia: Is it Possible that the Use of Lower Dose, Short-Acting Glucocorticoids has Increased the Risk of Adrenal Crises?"
01/01/2015 - "More work assessing the prevalence of adrenal insufficiency secondary to locally applied glucocorticoids is urgently needed. "
05/01/2013 - "This method allows fludrocortisone pharmacokinetic/pharmacodynamic studies when given at low dosage in an intensive care unit in case of adrenal insufficiency during a septic shock."
11/01/2005 - "Recent studies have proven that low doses of hydrocortisone and fludrocortisone can significantly reduce mortality in patients with relative adrenal insufficiency (RAI) without increasing adverse events. "
01/01/2011 - "The patient was known with Adrenal insufficiency and was treated optimally with fludrocortisone and prednisolone since seven years with no history of adrenal crisis. "
04/01/1986 - "Adverse effect of phenytoin on mineralocorticoid replacement with fludrocortisone in adrenal insufficiency."
08/20/1955 - "Metabolic effects of 9 alpha-fluorohydrocortisone and of cortisone in adrenal insufficiency."
06/01/2012 - "In addition, it examines the diagnosis of adrenal insufficiency in this population and provides an overview of recent studies on the use of steroids in treating hemodynamic instability in these children. "
01/01/2012 - "These studies reported that supplemental perioperative steroids were not required during surgery for patients with adrenal insufficiency. "
01/01/2009 - "These studies reported that supplemental perioperative steroids were not required during surgery for patients with adrenal insufficiency. "
08/01/1980 - "In conclusion, the present studies are consistent with the view that the concentrating defect seen in adrenal insufficiency is at least partly the result of the absence of the permissive effect that adrenal steroids exert on the ADH-induced reabsorption of water across the collecting duct. "
11/01/2014 - "Two days after cessation of steroids, she presented with non-specific symptoms of adrenal insufficiency (AI). "
|7.||Insulin (Novolin)FDA Link
03/01/2010 - "The insulin tolerance test (ITT) is considered the gold standard for the diagnosis of adrenal insufficiency (AI). "
09/01/2003 - "The present study was undertaken to compare the relative impact of three different regimes of glucocorticoid replacement in patients with adrenal insufficiency on parameters of bone turnover and insulin sensitivity. "
07/01/2014 - "The short Synacthen test (SST) is widely used as alternative test to the insulin tolerance test (ITT) to investigate central adrenal insufficiency (CAI), but the methodology and cut-off values of the SST are controversial. "
07/01/2014 - "Different cut-off values of the insulin tolerance test, the high-dose short Synacthen test (250 μg) and the low-dose short Synacthen test (1 μg) in assessing central adrenal insufficiency."
09/01/2012 - "We examined the effects of DHEAS on insulin action and the quality of life in female patients with hypopituitary hypoadrenalism. "
|8.||Dexamethasone (Maxidex)FDA LinkGeneric
08/01/2014 - "Adrenal insufficiency occurs in about half of the patients with SH if defined only by the pathological dexamethasone test. "
06/01/2012 - "Next, our data indicate that a four-day dexamethasone regimen during CAP does not lead to prolonged secondary adrenal insufficiency."
11/01/2007 - "Adrenal insufficiency can be assessed only by careful clinical evaluation, as the hormonal parameters are not reliable during receptor blockade, and is rapidly reversed by exogenous dexamethasone. "
12/01/2005 - "One subject (on long-term dexamethasone) developed hypoadrenalism, which responded to treatment. "
09/01/1997 - "We propose that conventional dexamethasone suppression-tests may be not enough sensitive in this kind of patients and that in selected cases the absence of controlateral uptake at scintigraphy may be more reliable in predicting post-surgical hypoadrenalism."
03/20/1965 - "[STUDY OF DISORDERS OF SODIUM AND WATER METABOLISM IN ADRENAL INSUFFICIENCY]."
04/30/1933 - "5. The balance studies show a striking loss of sodium from the body during the development of adrenal insufficiency. "
01/01/1989 - "One patient had adrenal insufficiency and the serum sodium corrected after steroid replacement. "
10/10/1987 - "The sodium retention associated with liquorice ingestion has been thought to be due to a direct mineralocorticoid effect, despite the fact that it does not seem to occur in patients or animals with severe adrenal insufficiency. "
09/28/1963 - "[DISORDERS OF SODIUM AND WATER METABOLISM DURING ADRENAL INSUFFICIENCY]."
01/01/2007 - "A third uncle failed to thrive during infancy but improved with a course of cortisone, then being untreated until further investigation revealed adrenal insufficiency. "
12/01/2014 - "However, our patient developed adrenal insufficiency after the oral cortisone supplementation was tapered. "
04/21/1978 - "This will reveal hypophyseal involvement and enable replacement hormonal therapy with cortisone to be added to symptomatic and antibiotic management in cases of concomitant hypophyseal and adrenal insufficiency."
05/01/1966 - "[Anomalies of steroid secretion during post-cortisone adrenal insufficiency]."
03/01/1965 - "[ACUTE ADRENAL INSUFFICIENCY IN THE COURSE OF CORTISONE THERAPY]."
04/01/2009 - "Adrenal-sparing surgery is an effective and safe alternative to total adrenalectomy for small, benign adrenal lesions and may decrease the risk of the development of adrenal insufficiency. "
08/01/1990 - "Pregnancy is permissible at a prolonged time following the onset of a stable clinical and hormonal remission, bilateral total adrenalectomy and compensation of chronic adrenal insufficiency. "
01/01/2015 - "The patient underwent left laparoscopic adrenalectomy with peri-operative glucocorticoid supplementation to prevent adrenal insufficiency. "
11/01/2013 - "She underwent right laparoscopic adrenalectomy and developed acute adrenal insufficiency. "
02/01/2013 - "An intended cortical-sparing adrenalectomy was performed in 39 patients and acute adrenal insufficiency developed in 1 (3%). "
|2.||Drug Therapy (Chemotherapy)
01/01/2013 - "The aim of this study was to report the response to various therapies and discuss the potential development of secondary adrenal insufficiency with cytotoxic chemotherapy. "
12/01/2013 - "According to our results, administration of chemotherapy and adrenal insufficiency are significant independent predictors of prognosis."
08/01/2010 - "Secondary adrenal insufficiency in an infant after intrathecal triple chemotherapy."
06/01/2000 - "We report a case of primary adrenal NHL associated with adrenal insufficiency which was successfully treated with steroid replacement and chemotherapy. "
05/01/1992 - "The authors suggest that such tests are essential if the staging of the NHL shows bilateral adrenal enlargement, and that the tests should be performed before chemotherapy begins because of the risk of acute adrenal insufficiency."
|3.||Transplantation (Transplant Recipients)
02/01/2010 - "A case of human intramuscular adrenal gland transplantation as a cure for chronic adrenal insufficiency."
07/01/2014 - "Four of these kidney transplant recipients presented with acute anterior MI; in these patients prophylactic steroid therapy prevented adrenal insufficiency, without any complication of the MI. "
06/01/2011 - "Although adrenal insufficiency can be managed with steroid replacement, transplantation of adrenocortical cells may represent a more definitive therapy. "
11/01/2010 - "Transplantation of functional adrenal cortex cells could reduce morbidity and increase the quality of life of patients with adrenal insufficiency. "
09/01/2009 - "Clinicians must be aware of the possibility of CMV-induced adrenal insufficiency in renal transplant recipients. "
|4.||Hormone Replacement Therapy (Therapy, Hormone Replacement)
03/01/2011 - "According to the international guidelines for medical practice, we believe that before considering hormone replacement therapy, a second test to confirm the diagnosis of GHD and adrenal insufficiency is required."
04/01/2009 - "Initiation of hormone replacement therapy in newly diagnosed adrenal insufficiency leads to rapid and impressive improvements. "
09/01/2008 - "Hormone-replacement therapy is necessary in all patients with adrenal insufficiency. "
10/01/2002 - "She was treated successfully for adrenal insufficiency acutely, and was later discharged on hormone replacement therapy. "
02/28/2004 - "The concept of relative adrenal insufficiency and peripheral syndrome of resistance to glycocorticosteroids have led to hormone replacement therapy during septic shock. "
01/01/2012 - "Safe anesthesia can be achieved by observing the preoperative development of tracheal aspiration, adrenal insufficiency and, autonomic dysfunction carefully and maintaining eye protection."
07/01/1964 - "[PREVENTION AND TREATMENT OF ADRENAL INSUFFICIENCY DURING OPERATIONS UNDER ANESTHESIA]."
04/01/2006 - "Anesthesia providers must be aware of the need for corticosteroid replacement not only in patients who have primary adrenal insufficiency but also in patients who have adrenal insufficiency resulting from long-term corticosteroid therapy. "
04/01/1985 - "Acute adrenal insufficiency in a patient with appendicitis during anesthesia."
02/06/1959 - "[Adrenal tumor, adrenalectomy, adrenal insufficiency and anesthesia]."