Sublingual Administration

Administration of a soluble dosage form by placement under the tongue.

Also Known As:

Administration, Sublingual; Administration, Sublingual Drug; Administrations, Sublingual; Administrations, Sublingual Drug; Drug Administrations, Sublingual; Sublingual Administrations; Sublingual Drug Administrations; Drug Administration, Sublingual; Sublingual Drug Administration

Networked: 235 relevant articles (20 outcomes, 29 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Drug Administration Routes: 28
    - Oral Administration: 17836
      - Sublingual Administration: 235

Experts

1.	Simons, Keith J: 3 articles (02/2018 - 07/2002)
2.	Barutcu, Irfan: 3 articles (05/2007 - 12/2004)
3.	Esen, Ali Metin: 3 articles (05/2007 - 12/2004)
4.	Chayama, Kazuaki: 3 articles (04/2007 - 05/2002)
5.	Goto, Chikara: 3 articles (04/2007 - 05/2002)
6.	Higashi, Yukihito: 3 articles (04/2007 - 05/2002)
7.	Deng, You-Bin: 3 articles (01/2003 - 04/2002)
8.	Li, Chun-Lei: 3 articles (01/2003 - 04/2002)
9.	Schug, Stephan A: 2 articles (09/2021 - 01/2009)
10.	Macchia, Daniele: 2 articles (01/2021 - 01/2019)

Related Diseases

1.	Heart Failure 01/30/1987 - "Because of the rapid action and feasability for sublingual administration of both drugs, their comparative hemodynamic and neurohumoral effects were studied in 12 patients with congestive heart failure. " 07/14/1989 - "The results indicate that sublingual administration of captopril in severe heart failure will achieve early and significant improvement in cardiac function." 06/01/2006 - "Although frequently reported, no study has investigated the effect on angiotensin II levels after sublingual administration in heart failure patients. " 07/14/1989 - "[Hemodynamics after sublingual administration of captopril in severe heart failure. " 03/01/1989 - "The plasma concentrations of 6-chloro-2-pyridylmethyl nitrate after sublingual administration were determined in six healthy male volunteers (venous plasma) and eleven patients (arterial plasma) with ischemic heart failure. "
2.	Neoplasms (Cancer) 01/01/2021 - "In the present study, we first established that the sublingual administration of type I IFN (IFN-I) is safe and feasible, and exerts antitumor effects both as monotherapy and in combination with chemotherapy in transplantable tumor models, i.e., B16-OVA melanoma and EG.7-OVA lymphoma. " 01/01/2023 - "Improved visualization of arterial supply of hepatic tumors during CT angiography using sublingual administration of glyceryl trinitrate." 06/01/2021 - "The study aimed to develop a method for sublingual administration of 5-aminolevulinic acid to patients and evaluate its effectiveness in fluorescence diagnostics and photodynamic therapy of neoplasms of the oral cavity and larynx. " 04/01/2010 - "Sublingual administration of fentanyl to cancer patients is an effective treatment for breakthrough pain: results from a randomized phase II study." 02/01/2005 - "Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain."
3.	Allergic Rhinitis 01/01/2016 - "Intralymphatic administration of an OVA-FlaB mixture was more effective in alleviating allergic inflammation than intranasal and sublingual administration in a mouse model of allergic rhinitis. " 01/11/2019 - "BACKGROUND The aim of this study was to determine the efficacy of sublingual administration of Dermatophagoides farinae drops for the treatment of allergic rhinitis (AR) accompanied by adenoid hypertrophy and the effect on immune function in children. " 01/11/2019 - "Efficacy of Sublingual Administration of Dermatophagoides Farinae Drops for Treatment of Pediatric Allergic Rhinitis Accompanied by Adenoid Hypertrophy and Improvement of Immune Function." 10/01/2016 - "Clinical evaluation of sublingual administration of dust mite drops in the treatment of allergic asthma and allergic rhinitis of children." 01/01/2018 - "Allergen-specific immunotherapy (AIT) is indicated for patients with allergic asthma and/or allergic rhinitis, and can be implemented by either subcutaneous injection (SCIT) or sublingual administration (SLIT). "
4.	Missed Abortion 04/01/2017 - "The followings were found to be independently associated with cervical dilatation in a linear regression analysis: sublingual administration, gestational age, missed abortion, and previous vaginal delivery. " 10/01/2016 - "Sublingual administration of misoprostol is more effective than its vaginal administration in missed abortion management. " 06/01/2010 - "To evaluate the efficacy of two routes of misoprostol administration (sublingual and vaginal) for the treatment of missed abortion. " 10/01/2016 - "The aim of the present study is to compare between sublingual administration of misoprostol and vaginal administration in the management of missed abortion. "
5.	Infections 05/01/2013 - "Sublingual administration of Lactobacillus rhamnosus affects respiratory immune responses and facilitates protection against influenza virus infection in mice." 05/01/2013 - "Sublingual administration of Lactobacillus rhamnosus provided enhanced protection against influenza virus infection by enhancing mucosal secretory IgA production, and T and NK cell activity. " 02/01/2013 - "Sublingual administration of bacteria-expressed influenza virus hemagglutinin 1 (HA1) induces protection against infection with 2009 pandemic H1N1 influenza virus."

Related Drugs and Biologics

1.	Misoprostol (Cytotec)
2.	Nitroglycerin (Dynamite)
3.	Captopril (Capoten)
4.	Nifedipine (Adalat)
5.	Isosorbide Dinitrate (Isordil)
6.	Nitrates
7.	Fentanyl (Sublimaze)
8.	Vasodilator Agents (Vasodilators)
9.	Allergens
10.	Sildenafil Citrate (Viagra)

Related Therapies and Procedures

1.	Intravaginal Administration
2.	Immunotherapy
3.	Oral Administration
4.	Therapeutics
5.	Catheters