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Adenylosuccinate Synthase (Synthase, Adenylosuccinate)

A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyzes the synthesis of adenylosuccinate from GTP; IMP; and aspartate with the formation of orthophosphate and GDP. EC 6.3.4.4.
Also Known As:
Synthase, Adenylosuccinate; Adenylosuccinate Synthetase; Succino-AMP Synthetase; Succino AMP Synthetase; Synthetase, Adenylosuccinate; Synthetase, Succino-AMP; IMP:L-aspartate ligase (GDP-forming)
Networked: 31 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Hu, Feizi: 1 article (05/2022)
2. Liu, Qin: 1 article (05/2022)
3. Wang, Zhuang: 1 article (05/2022)
4. Zhang, Yuanxing: 1 article (05/2022)
5. Dewulf, Joseph P: 1 article (01/2022)
6. Marie, Sandrine: 1 article (01/2022)
7. Nassogne, Marie-Cécile: 1 article (01/2022)
8. Elliott, Gregory I: 1 article (12/2020)
9. Tibrewal, Nidhi: 1 article (12/2020)
10. Arumugam, Ramamani: 1 article (10/2015)

Related Diseases

1. Hyperuricemia
2. Neoplasms (Cancer)
3. Ascites
4. Lymphoma (Lymphomas)
5. T-Cell Lymphoma (Lymphoma, T Cell)

Related Drugs and Biologics

1. Enzymes
2. IMP Dehydrogenase
3. purine
4. Adenylosuccinate Synthase (Synthase, Adenylosuccinate)
5. Adenylosuccinate Lyase
6. Inosine Monophosphate (IMP)
7. alanosine (SDX 102)
8. Ribonucleotides
9. Ligases (Synthetase)
10. Isoenzymes

Related Therapies and Procedures

1. Therapeutics