|1.||Burnstock, Geoffrey: 38 articles (03/2014 - 03/2002)|
|2.||Delivoria-Papadopoulos, Maria: 35 articles (08/2012 - 01/2002)|
|3.||Ambudkar, Suresh V: 28 articles (11/2015 - 10/2003)|
|4.||Terzic, Andre: 27 articles (01/2013 - 04/2003)|
|5.||Mishra, Om P: 25 articles (08/2010 - 01/2002)|
|6.||Seino, Susumu: 24 articles (09/2012 - 02/2002)|
|7.||Cree, Ian A: 23 articles (01/2012 - 07/2002)|
|8.||Di Virgilio, Francesco: 22 articles (06/2013 - 04/2003)|
|9.||Chen, Zhe-Sheng: 21 articles (11/2015 - 02/2003)|
|10.||Stanley, Charles A: 21 articles (07/2013 - 07/2003)|
04/04/2003 - "We recently demonstrated that it induces potent protective effects against ischemia-reperfusion (I-R) injury in rabbit hearts through the opening of mitochondrial ATP-dependent K+ channels. "
10/01/1999 - "Group IV also showed a significant marked inhibition of the decrease in ATP during global ischemia (59+/-5%) and a more significant improvement on recovery of ATP during postischemic reperfusion (86+/-3%) compared with the other 3 groups. "
08/01/1997 - "Group IV also showed a significantly marked improvement of ATP, CrP, and pH and significant suppression in Pi during low-flow ischemia compared with Group III. These were no differences in LV Dev.P and coronary flow among any groups. "
12/01/1990 - "Active force development in acute ischemia is inhibited by the accumulation of ischemic metabolic products (H+, inorganic phosphate (Pi), Mg++) but not by a marked decrease of [ATP]. "
07/01/1990 - "Restoration of CrP levels after complete reperfusion was also significantly greater in group V than in group II. The recovery of ATP after complete reperfusion was also much better in group V being comparable to those in group I, although the total duration of ischemia was longer in group V than in group I. These results indicate the beneficial effects of low-flow perfusion on the preservation during ischemia and recovery after reperfusion of myocardial HEP."
01/01/2011 - "We then confirmed the presence of autophagy under hypoxic conditions and demonstrated that the inhibition of this catabolic process dramatically reduced the ATP levels in hypoxic cells and stimulated hypoxia-induced cell death. "
12/01/1985 - "Decreasing the extracellular Ca to 2.5 microM decreased LDH release significantly during anoxia, suggesting that plasma membrane damage during anoxia may be associated with increased intracellular free Ca. Addition of Mg-adenosine triphosphate during anoxia dramatically improved recovery of all the measured parameters after the anoxic period."
03/01/2006 - "Anoxia triggered a marked decrease of metabolic activity (measured by microcalorimetry) and of ATP levels in both species. "
01/20/1992 - "This enhancement should provide more ATP for energy-requiring ion transport processes, and lead (1) to a delayed onset of complete depolarization of CA1 pyramidal cells during anoxia (anoxic depolarization) and (2) to greater ion transport activity following anoxia. "
11/01/1990 - "Acute hypoxia, which leads to a decrease in cellular ATP levels, was responsible for a marked decrease in myocardial performance, while R1 increased (+66 +/- 8%, P less than 0.05) and R2 decreased (-14 +/- 1%, P less than 0.05). "
09/01/2012 - "Concurrently, intracellular ATP levels increased markedly; thus, irradiation (0.225 J/cm(2)) for 5 min provided the best results in terms of the highest degree of cancer cell apoptosis. "
09/01/2015 - "The DHA-induced metabolic changes led to a marked decrease of intracellular ATP levels by 50% in both cancer cell lines, which mediated phosphorylation of metabolic stress marker, AMPK, at Thr172. "
08/28/2008 - "Consistently, expression of both K(ATP) and K(Ca) channels in 9L tumors was increased to a significantly greater extent in Wistar rats (allogeneic) as compared to Fischer rats (syngeneic). "
06/01/2015 - "Therefore, signaling pathways from Oct-3/4 to ATP binding cassette transporter G2 should be intensively elucidated to develop new therapeutic interventions for better efficacy of anti-cancer drugs."
01/01/2011 - "Understanding the ATP-linked mechanism of NAMPT and the catalytic site machinery may permit the design of improved NAMPT inhibitors as more efficient drugs against cancer."
07/01/2004 - "The above results, therefore, suggest to us that IP by activation of K(ATP) channels can afford protection against the ischemia-reperfusion injury in the hypertrophied heart."
07/01/2004 - "In this study we have demonstrated the role of ischemic preconditioning (IP) in preventing the reperfusion injury of the hypertrophied heart by activation of the depleted K(ATP) channels. "
07/15/1996 - "This study examines the effect of intestinal reperfusion injury (IIR) on renal blood flow and relates this temporally to changes in renal ATP levels and renal tubular function. "
01/01/1989 - "From this study it was concluded that PEP and ATP partially protect skeletal muscle from ischaemia and reperfusion injury."
12/01/2015 - "δPKC interaction with the d subunit of F1Fo ATP synthase impairs energetics and exacerbates ischemia/reperfusion injury in isolated rat hearts."
10/01/1993 - "3. Comparison of the concentrations of high-energy phosphate metabolites before and after electric shock using 31P-NMR revealed a marked decrease in beta-ATP and an increase in that of Pi. "
06/01/2000 - "Heat-shock preconditioning significantly improved the survival rate, suppressed the increase in liver-related enzyme levels and maintained adenosine triphosphate levels (P<0.01 each). "
01/01/1996 - "Administration of Lip-ATP significantly improved hepatic blood flow during shock (13.2 +/- 1.7 ml/min/100 g tissue in the Lip-ATP group vs. 9.4 +/- 2.2, in the control group, and 8.9 +/- 2.9 in the free ATP group) and during reperfusion (20.9 +/- 2.3, 16.3 +/- 2.2, and 16.2 +/- 1.8 ml/min/100 g tissue, respectively). "
09/01/1977 - "It has been shown that infusion of ATP-MgCl2 proved beneficial in the treatment of shock; however, it is not known whether this effect is due to improvement in the microcirculation or direct provision of energy or a combination of the above or other effects. "
09/01/2008 - "Before discharge from the hospital each patient had an electrophysiological study (EPS) performed through the device, to assess the efficacy of ATP and low-joule shock at terminating VFVT. "
|1.||Adenosine Triphosphate (ATP)
|3.||Potassium Channels (Potassium Channel)
|8.||Adenosine Diphosphate (ADP)
|10.||Nicorandil (SG 75)
|1.||Drug Therapy (Chemotherapy)
|2.||Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
|3.||Induced Heart Arrest (Cardioplegia)