|1.||Prieto, Luis: 12 articles (02/2015 - 06/2002)|
|2.||Harder, Jürgen: 11 articles (11/2014 - 02/2006)|
|3.||Postma, D S: 11 articles (03/2011 - 05/2000)|
|4.||Hardie, D Grahame: 10 articles (01/2014 - 10/2002)|
|5.||Viollet, Benoit: 10 articles (12/2013 - 09/2004)|
|6.||Lipworth, Brian J: 10 articles (01/2011 - 02/2003)|
|7.||Gläser, Regine: 9 articles (11/2014 - 06/2007)|
|8.||Lipworth, B J: 9 articles (03/2009 - 10/2000)|
|9.||Kuttan, Girija: 8 articles (02/2012 - 06/2007)|
|10.||Chen, Zhijian J: 7 articles (10/2015 - 02/2013)|
|1.||Asthma (Bronchial Asthma)
01/01/2010 - "Can AMP induce sputum eosinophils, even in subjects with complete asthma remission?"
03/01/2012 - "PF5212372 significantly inhibited AMP-induced contraction of human bronchi (81% inhibition; p < 0.001); this finding, together with the ability of this drug to be effective in a wide range of preclinical asthma models, suggests that inhibition of cPLA(2)α with PF-5212372 may represent a new therapeutic option for the treatment of asthma."
09/01/2000 - "The responsiveness to both AMP and MCh of subjects in clinical remission was significantly higher as compared with responsiveness of healthy controls, and lower than responsiveness of subjects with current asthma. "
03/17/1997 - "More research is required on why AMPs are not more generally used and, more importantly, on what elements within the AMP model are useful and effective for people with asthma and likely to be used by their general practitioners (GPs)."
04/01/2004 - "Repeated dosing with FEX and ML as add-on therapy improved AMP PC(20) and other surrogate inflammatory markers along with asthma diary outcomes in ICS-treated atopic asthmatic patients. "
08/01/2013 - "Disease severity was significantly improved 7 days after infection, at which time AMP expression was returning to baseline. "
12/01/2013 - "A single-dose AMP regimen was shown to be effective and feasible for prevention of perioperative infection in urological surgery."
12/01/2010 - "In case mice given a combination of Amp B (0.5mg dose) plus MAb B6.1 at 2h post-infection - a condition of developing no therapeutic efficacy, the combination also reduced disease severity. "
09/01/2008 - "A single-dose regimen of AMP was effective for prevention ofperioperative infections including SSI, UTI, and RI in endoscopic-instrumental, clean, and clean-contaminated surgical procedures in urology."
06/01/2014 - "These compounds display an array of immunomodulatory effects that remain to be investigated in further detail to establish their role in the clearance of infection and possible modulation of AMP expression. "
09/01/2009 - "Our data support a selective use of blind-PD because (1) a significant portion (65%) of benign ampullary neoplasms can be safely and effectively treated by AMP, (2) blind-PD does not treat ampullary cancer at earlier stage, and (3) blind-PD is associated with significantly more complications and significantly longer hospital stay than AMP. "
11/01/2013 - "Taken together, these findings indicate that AMP has antitumor activity in vivo at least partly via improving immune responses of host organism, and seems to be safe and effective for the use of anti-tumor therapy."
09/01/2015 - "This study was aimed at designing a new AMP containing NGR and testing their biological activity against different types of tumor cells with varying CD13 and αvβ3 expression. "
01/01/1998 - "In order to study potential changes in phosphodiesterase (PDE) activity associated with malignant transformation, normal primary keratinocytes and cells corresponding to different stages of epidermal tumor development in mouse skin were analyzed with respect to their 3',5'-cyclic adenosine monophosphate (cAMP) hydrolyzing activity. "
11/01/2015 - "The AMP-based NGS method is applicable for profiling tumor variants. "
|4.||Body Weight (Weight, Body)
11/01/2008 - "After 10weeks of feeding trial, growth performances of fish (initial body weight, 35g) fed the AMP0 were significantly lower compared to that of fish fed diets supplemented with AMP. "
05/01/2015 - "Cows gained less body weight on the DMP diet, compared with AMP. "
05/01/2015 - "After 96 h, in vitro models were run simulating 10 mg DAP/kg body weight/day, 600 mg CPT every 8 h (q8h), 2 g AMP q4h, and 1 g ERT q24h, both alone and in combination against all strains. "
09/01/2014 - "After successful return of spontaneous circulation (ROSC, n=40), animals were randomized either to placebo group (n=14) or AMP group (800 mg/kg body weight, n=14). "
03/01/2014 - "In addition, despite recent evidence to support a role for intestinal epithelial LepRb signaling in pathogen susceptibility, ablation of LepRb from the intestinal epithelium fails to alter body weight, composition of the microbiota, or AMP expression, suggesting a role for LepRb elsewhere for this regulation. "
07/01/2003 - "The clinical efficacy of Parietaria SIT was exclusively associated with attenuation in seasonal worsening of PC15 AMP, suggesting that AMP may be useful in monitoring changes in allergic inflammation of the airways."
10/01/2001 - "Improvement in PC20 AMP was solely related to reduction in airway inflammation (i.e., change in the number of sputum eosinophils, lymphocytes, epithelial cells, and concentration of NO in exhaled air). "
01/01/2016 - "Epithelial cells and endothelial cells lose barrier function in the context of allergic airway inflammation, and this could be at least partially remedied by increasing the intracellular cyclic adenosine monophosphate levels through phosphodiesterase inhibition."
12/01/2015 - "Using BALB/c mice as the animal model, AMP-QDs were found to be detained in immune organs but did not evoke robust inflammation responses or obvious histopathological abnormalities, which reveals low immunotoxicity in vivo. "
11/01/2015 - "The inflammation in the VCZ and liposomal Amp-B groups was milder than that in the control group. "
|1.||Methacholine Chloride (Methacholine)
|2.||Adenosine Diphosphate (ADP)
|3.||Adenosine Triphosphate (ATP)
|4.||Protein Kinases (Protein Kinase)
|5.||Amphotericin B (Amphotericin)
|6.||liposomal amphotericin B
|7.||Nitric Oxide (Nitrogen Monoxide)
|9.||5'-Guanylic Acid (GMP)
|10.||Messenger RNA (mRNA)
|1.||Drug Therapy (Chemotherapy)
|4.||Continuous Positive Airway Pressure
|5.||Heterologous Transplantation (Xenotransplantation)