|1.||Aiuti, Alessandro: 20 articles (04/2015 - 06/2002)|
|2.||Blackburn, Michael R: 16 articles (01/2011 - 02/2002)|
|3.||Fröde, Tânia Silvia: 12 articles (12/2015 - 10/2002)|
|4.||Gaspar, H Bobby: 11 articles (05/2015 - 10/2006)|
|5.||Hershfield, Michael S: 8 articles (01/2015 - 05/2004)|
|6.||Gloria-Bottini, F: 8 articles (07/2010 - 12/2002)|
|7.||Titarenko, O T: 8 articles (01/2010 - 01/2000)|
|8.||Schetinger, Maria Rosa Chitolina: 7 articles (05/2015 - 02/2012)|
|9.||Kohn, Donald B: 7 articles (01/2015 - 10/2003)|
|10.||Thrasher, Adrian J: 7 articles (03/2014 - 10/2006)|
|1.||Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
01/01/2006 - "Indeed, the first clinical gene therapy trial was safely performed and was in part, effective for adenosine deaminase (ADA) deficiency patients, a type of severe combined immunodeficiency diseases (SCID). "
03/01/2014 - "Gene transfer into autologous hematopoietic stem cells by γ-retroviral vectors (gRV) is an effective treatment for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID). "
11/01/2013 - "Improved outcomes for 'difficult' conditions [adenosine deaminase-severe combined immunodeficiency (ADA-SCID), major histocompatibility complex class II deficiency] and potential advantages of using cord blood as a stem cell source have also been described. "
12/01/1993 - "Severe combined immunodeficiency of reduced severity due to homozygosity for an adenosine deaminase missense mutation (Arg253Pro)."
09/01/2015 - "In fact, the first human gene therapy trial performed involved the implantation of autologous bone marrow cells transduced ex vivo with gamma retrovirus vectors expressing adenosine deaminase in a patient with severe combined immunodeficiency. "
|2.||Hairy Cell Leukemia
01/01/1994 - "Since the introduction of adenosine deaminase analogues the vast majority of patients with Hairy cell leukemia obtain lasting complete remission. "
06/01/1988 - "This antimetabolite, an adenosine deaminase inhibitor, also shows particular efficacy in hairy cell leukemia. "
09/01/1994 - "Pentostatin, an adenosine deaminase inhibitor, has been approved for the treatment of refractory hairy cell leukemia. "
07/01/1992 - "Pentostatin: an adenosine deaminase inhibitor for the treatment of hairy cell leukemia."
02/01/1989 - "2'-Deoxycoformycin (pentostatin [dCF]), a potent inhibitor of adenosine deaminase (ADA), was administered in a biweekly low-dose (2 to 4 mg/m2) intravenous (IV) schedule to patients with advanced hairy cell leukemia. "
03/01/2013 - "In some studies, the level of adenosine deaminase (ADA) in sputum and effusion liquids was used for the diagnosis of tuberculosis (TB). "
01/01/2013 - "This study was set up to investigate the diagnostic value of serum Adenosine deaminase in diagnosis of tuberculosis. "
09/01/2006 - "Adenosine deaminase (ADA) levels are used for diagnosing tuberculosis in several locations and although many studies have evaluated ADA levels in ascitic fluid. "
10/01/2002 - "The aim of our study was to compare the significance of different adenosine deaminase dependent parameters in diagnosing tuberculosis. "
11/01/1992 - "Adenosine deaminase (ADA) was estimated in 84 pleural, 140 peritoneal and 136 cerebrospinal fluids to study its diagnostic usefulness as a routine test for tuberculosis. "
01/01/2004 - "The results indicate that serum adenosine deaminase activity may be helpful in the diagnosis and follow-up of head and neck cancers. "
12/01/2012 - "The relationship between adenosine deaminase and various cancers has been investigated in several studies. "
08/05/2005 - "This study was also extended to monitor adenosine deaminase activity in different cancer cells of hematological origin. "
09/01/1986 - "Adenosine deaminase complexing protein in cancer studies."
02/01/1958 - "[Studies on increase of diagnostic possibilities in cancer; determination of activity of adenosine deaminase in plasma]."
12/01/1996 - "Injection of adenosine deaminase into the eye before ischemia seemed to potentiate the ischemia-reperfusion effect because the reduction of the b-wave was almost complete (8% +/- 4%, n = 6). "
11/01/1988 - "Inhibition of adenosine deaminase during ischemia results in a injury similar to that seen after a shorter period of insult."
11/01/1988 - "Metabolic and functional consequences of inhibiting adenosine deaminase during renal ischemia in rats."
05/01/2015 - "Neuroinflammation after neonatal hypoxia-ischemia is associated with alterations in the purinergic system: adenosine deaminase 1 isoenzyme is the most predominant after insult."
12/01/2009 - "Adenosine deaminase activity, lipid peroxidation and astrocyte responses in the cerebral cortex of rats after neonatal hypoxia ischemia."
|4.||Interferon-gamma (Interferon, gamma)
|7.||Adenosine Triphosphate (ATP)
|9.||Biological Markers (Surrogate Marker)
|1.||Enzyme Replacement Therapy
|2.||Drug Therapy (Chemotherapy)
|5.||Induced Heart Arrest (Cardioplegia)