|1.||Grunfeld, Carl: 15 articles (04/2011 - 04/2002)|
|2.||Ramadori, Giuliano: 14 articles (01/2013 - 10/2002)|
|3.||Feingold, Kenneth R: 13 articles (04/2011 - 04/2002)|
|4.||Herndon, David N: 11 articles (06/2013 - 01/2002)|
|5.||Shigenaga, Judy K: 11 articles (04/2011 - 04/2002)|
|6.||Jeschke, Marc G: 9 articles (06/2013 - 01/2002)|
|7.||Wallin, Håkan: 8 articles (07/2015 - 01/2009)|
|8.||Friis, Henrik: 7 articles (10/2015 - 05/2003)|
|9.||Saber, Anne T: 7 articles (07/2015 - 01/2009)|
|10.||Vogel, Ulla: 7 articles (07/2015 - 01/2009)|
|1.||Interleukin-6 (Interleukin 6)IBA
04/01/1994 - "The serum concentration of TNF of IL-6 does not correlate with the presence of an acute-phase response, whereas rates of cytokine production by peripheral blood mononuclear cells are significantly greater in patients with such a response. "
11/01/2006 - "Interleukin-6 (IL-6) is a major regulator of the acute phase reaction in the liver and is thought to mediate protective effects in response to hepatotoxins. "
02/01/2004 - "The goal of this study was to determine if there is a relationship between urine albumin excretion and interleukin-6, a key mediator of acute phase reaction. "
03/01/2001 - "Physical examination was noncontributory, and extensive studies revealed only a marked acute-phase response associated with increased serum IL-6 levels. "
03/01/1996 - "Serum levels of albumin and interleukin-6 (IL-6) were compared with CRP levels in order to study the acute phase response. "
|2.||Fibrinogen (Factor I)FDA Link
11/01/2007 - "They were found to be significantly younger and lean, had an improved lipid profile and an attenuated acute-phase response in terms of lower erythrocyte sedimentation rate and fibrinogen concentration as well as white blood cell count. "
01/01/2007 - "Our conclusion is that the pro-aggregating properties of fibrinogen following intense physical activity are probable counterbalanced by the anti-aggregatory properties of an improved lipid profile and an attenuated acute phase response."
08/01/1993 - "The results of these studies confirmed the induction of the acute-phase response by mrIL-6, as reflected in an approximate doubling in circulating levels of fibrinogen and C3. "
08/01/1986 - "The technique was then employed in a limited clinical study of nine patients undergoing infrainguinal vascular reconstruction to evaluate the effect of operation and the associated increase in serum fibrinogen levels, resulting from the acute phase reaction, on blood viscosity. "
06/01/2015 - "Variation of fibrinogen oligosaccharide structure in the acute phase response: Possible haemorrhagic implications."
02/01/2004 - "The decreased PLP levels occurred despite a significant improvement in the acute phase response (increased albumin [P < 0.001] and reduced C-reactive protein levels [P < 0.01]). "
01/01/2015 - "In the ImmunoGuard™ study (24 participants) acute phase response indicators (including erythrocyte sedimentation rate, white blood cell count and C-reactive protein) were not reduced after one month treatment. "
03/01/2005 - "The aim of the present study was to evaluate (1) the relation between the MBL pathway and postoperative infectious complications and survival of patients resected for CRC, and (2) the role of MBL in acute phase response compared to C-reactive protein (CRP). "
10/06/1997 - "It is often of great clinical value to monitor the acute phase response in humans but the assays used to measure the acute response in man (e.g., erythrocyte sedimentation rate and C-reactive protein) is less well suited for experimental studies in the rat. "
12/01/1979 - "Studies of the acute phase response were carried out in nine patients following elective surgery, with C-reactive protein (CRP) used as the control protein: six patients showed no rise in beta 1H levels and three showed a small (20%) rise whereas all exhibited a gross rise in CRP. "
|4.||Proteins (Proteins, Gene)IBA
02/01/2011 - "This study confirmed that the intramuscular administration of TTX increases the gene expression of the acute-phase response proteins in the liver of puffer fish T. "
01/01/2004 - "The results of this study indicate that in drug-induced maculopapular eruptions the acute phase response can be initiated and that the observed increased activity of the examined proteins lasts longer than the clinical symptoms of the disease."
01/01/2002 - "The results of this study indicate that in severe drug-induced skin reactions the acute phase response can be initiated and that the increased activity of examined proteins is longer observed than clinical symptoms of the disease."
02/01/1993 - "To study the effects of changed synthesis on intracellular transport of secretory proteins, an acute phase response was induced in rats. "
07/01/2015 - "Functional analysis revealed that endometrial proteins with altered abundance on Day 12 irrespective of the reproductive status were related to growth and remodeling, acute phase response and free radical scavenging, whereas transport and small molecule biochemistry were the functions activated in the pregnant endometrium as compared to the cyclic endometrium. "
08/01/2002 - "The possibility of a decreased renal clearance of CRP and/or cytokines as a cause of an activated acute-phase response is discussed. "
07/07/2005 - "Irradiation is likely to cause an acute phase response, and the cytokines studied may be used to monitor this clinically important response in further trials."
01/01/2004 - "Several in vivo studies have demonstrated an acute-phase reaction after the first administration of aminobisphosphonates, with a significant increase in the main pro-inflammatory cytokines. "
11/01/1998 - "In the present study, we have analyzed the direct effects of cytokines, which mediate the acute-phase response in liver, on connexin expression and gap-junctional intercellular communication in immortalized MHSV12 mouse hepatocytes. "
02/01/1997 - "These studies suggest that AAG may function as an immune-modulator in the acute phase response, possibly by counter-regulating the activity of macrophage pro-inflammatory cytokines."
07/01/2007 - "In the present study, turpentine oil was injected in the hind limb muscle of the rat to stimulate an acute-phase response (APR). "
01/15/2006 - "To study the way in which the acute-phase response induced by sterile tissue injury influences pulmonary host defense, mice were injected subcutaneously with turpentine or saline in both hind limbs either 2 or 5 days before intranasal inoculation with A. "
04/01/2004 - "These in vitro results were confirmed by in vivo studies in IL-6(-/-) mice injected with turpentine, an experimental model of acute-phase response. "
01/01/1996 - "In this study, an acute phase response was induced by subcutaneous turpentine injection in rats. "
04/01/2011 - "Intra-muscular injection of turpentine oil was used to induce acute phase response (APR) in Atlantic cod (Gadus morhua L.). "
|7.||Interleukin-1 (Interleukin 1)IBA
07/01/1999 - "Our data suggest that centrally injected IL-1 induces higher circulating and hepatic IL-1 levels and contributes to the fact that the i.c.v. route of administration is particularly effective in inducing a liver acute-phase response."
12/01/1997 - "The objective was to study the relationship between the levels of interleukin-1 receptor antagonist (IL-1Ra) and disease activity and the acute-phase response in SLE patients with and without renal involvement. "
03/01/2013 - "However, interleukin-1 receptor antagonist was also upregulated, and the acute-phase response pathways and oxidant capacity decreased or remained unchanged, marking a concomitant activation of an anti-inflammatory response. "
01/01/2008 - "In the liver, IL-1 initiates the acute phase response resulting in an increase in hepatic protein synthesis and decreased albumin production IL-1 also plays an important role in immune functions, having effects on macrophages/monocytes, T lymphocytes, B lymphocytes, NK cells, and LAK cells. "
02/16/2007 - "Interleukin-1 receptor antagonist induction as an additional mechanism for liver receptor homolog-1 to negatively regulate the hepatic acute phase response."
|8.||Transcription Factors (Transcription Factor)IBA
03/19/2001 - "In this study we asked whether the heavy metal treatment affects the regulation of the C/EBP transcription factors which play a key role in regulation of the acute phase response gene. "
07/01/2015 - "The SNPs at positions -221 and -611 were located in regions predicted to bind to transcription factors linked to the acute phase response."
05/01/2013 - "In conjunction with the acute-phase response, additional biological pathways are induced in the liver and are dependent on the transcription factors STAT3 and NF-κB, but these responses are poorly understood. "
04/01/2011 - "Thus, ChREBP joins a growing list of transcription factors that are regulated during the acute phase response."
05/01/2008 - "These genes were mainly associated with acute-phase response, cell adhesion, cell cycle and growth, growth factor, ion binding, metabolism, proteolysis and transcription factor. "
|9.||NF-kappa B (NF-kB)IBA
01/01/2007 - "T(3) administration involving transient oxidative stress in the liver exerts significant protection against IR injury, a novel preconditioning maneuver that is associated with NF-kappaB and STAT3 activation and acute-phase response."
06/01/2009 - "Both Stat3 and NF-kappaB have been shown to regulate the expression of genes involved in inflammatory signalling and the acute phase response. "
09/01/2007 - "The upcoming group of NF-kappaB inhibitors may have a place in the treatment of the acute-phase response."
09/01/2002 - "NF-kappaB plays a role in immune response, cellular adhesion or acute phase response. "
03/01/2000 - "In the adult liver, activation of the NF-kappaB heterodimer RelA/p50 can cause hepatocyte proliferation, apoptosis, or the induction of acute-phase response genes. "
01/13/2015 - "This altered profile associated with enhanced acute phase response, deregulated cholesterol metabolism, and steatoheptatitis. "
04/01/2010 - "The acute phase response inhibits reverse cholesterol transport."
02/01/2009 - "The net result of this remodeling was a relative preservation of ABCA1- and ABCG1-dependent cholesterol efflux during the acute phase response. "
01/01/2006 - "Total cholesterol (TC) was a negative predictor for AMI in both sexes, because mean TC level of AMI patients was less than that of controls probably because of acute phase reaction. "
10/01/2001 - "Significant induction of cholesterol levels and SREBP-1 activation was observed only in C57Bl/6J mice, indicating that cytokine production is crucial for the regulation of SREBP-1, and that the transcriptional activation of cholesterol biosynthesis may be part of the acute-phase response."
05/15/2014 - "We analyzed graft function, the acute-phase response, and oxidative stress in the pancreatic graft monitoring membrane fluidity and lipid peroxidation. "
10/01/2011 - "The acute phase response after surgical reconstruction remains poorly defined but may influence graft integration through modulation of host tissue remodelling. "
01/01/2010 - "[Acute phase reaction of different macromolecule vascular grafts healing in rat muscle]."
03/15/2003 - "The aim of this study is to investigate the gene expression pattern of acute phase response in relation to graft size in a rat-liver transplantation model. "
01/01/1992 - "Due to the stress imposed by the process of bone marrow transplantation (BMT), we hypothesized that individuals receiving such a transplant underwent an acute phase response (APR). "
02/01/2006 - "First, a mouse model of acute phase response was established by intraperitoneal injection of LPS. "
03/01/2002 - "Induction of an acute phase response in connexin-32-deficient mice by intraperitoneal injection of lipopolysaccharide increased dye coupling by 33%, probably due to upregulation of connexin-26-containing gap junction channels."
04/01/2000 - "Although intraperitoneal injection of mIL-1, mIL-6 as well as mTNF-alpha did not induce an acute-phase response, Cx32 protein expression was diminished, suggesting that post-transcriptional downregulation of Cx32 preceded the acute-phase response. "
04/01/2000 - "Acute-phase response was triggered by intraperitoneal injection of lipopolysaccharide (LPS). "
10/01/1991 - "The acute-phase reaction was induced by intraperitoneal injections of bacterial lipopolysaccharide (LPS). "
|3.||Enteral Nutrition (Feeding, Tube)
03/01/1998 - "The acute phase response and disease severity scores were significantly improved following enteral nutrition (CRP: 156 (117-222) to 84 (50-141), p < 0.005; APACHE II scores 8 (6-10) to 6 (4-8), p < 0.0001) without change in the CT scan scores. "
03/13/2005 - "Enteral feeding seems to be the only proven tool in attenuating acute phase response and improving disease severity."
01/01/2003 - "Modulation by enteral nutrition of the acute phase response and immune functions."
01/01/2010 - "Perhaps, the best therapeutic option would be to favor early hypometabolism during the ischemia-reperfusion phase, to boost the antienzymatic metabolism and to reduce hypermetabolism during the leukocytic phase through the early administration of enteral nutrition and the modulation of the acute phase response. "
03/01/1998 - "Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis."
|4.||Cardiopulmonary Bypass (Heart-Lung Bypass)
12/01/2007 - "This study characterized compositional changes in LDL and HDL during the acute phase response following cardiac surgery with cardiopulmonary bypass. "
08/01/1996 - "This study demonstrated a marked acute-phase response to operation; the greater response to procedures with cardiopulmonary bypass was abrogated by intraoperative steroid administration. "
07/01/2008 - "Cardiac surgery with cardiopulmonary bypass (CPB) induces an acute phase reaction that is implicated in the pathogenesis of several postoperative complications. "
08/01/2007 - "Cardiopulmonary bypass-induced acute liver injury is a life-threatening complication thought to be associated with the inflammatory response and the acute-phase response. "
06/01/2007 - "Cardiopulmonary bypass (CPB)-induced acute liver injury is a life-threatening complication after cardiac surgery and is thought to be associated with inflammatory response and acute-phase response (APR). "
|5.||Prostatectomy (Retropubic Prostatectomy)
05/01/2008 - "To evaluate whether robotically assisted laparoscopic prostatectomy (RALP) is less invasive than radical retropubic prostatectomy (RRP), as experimental studies suggest that the acute phase reaction is proportional to surgery-induced tissue damage. "
06/01/2009 - "Furthermore, MP-associated TF PCA was higher in patients with (n=29) than in those without (n=39) laboratory evidence of an acute-phase reaction (p=0.004) and decreased to normal levels within one week after radical prostatectomy. "
05/01/2013 - "In this small prospective randomized study, thoracic epidural analgesia reduced the early postoperative stress response but not the acute inflammatory response after radical retrobupic prostatectomy, suggesting that other pathways are involved during the acute phase reaction."
02/01/2000 - "This study evaluated the effects of sodium nitroprusside-induced controlled hypotension on the acute phase response in patients undergoing radical prostatectomy. "
07/01/2011 - "Acute phase response to nitroprusside-induced controlled hypotension in patients undergoing radical prostatectomy."