|1.||Duarte, Iola F: 1 article (08/2011)|
|2.||Almeida, Maria do Céu: 1 article (08/2011)|
|3.||Graça, Gonçalo: 1 article (08/2011)|
|4.||Diaz, Sílvia O: 1 article (08/2011)|
|5.||Pinto, Joana: 1 article (08/2011)|
|6.||Barros, António S: 1 article (08/2011)|
|7.||Goodfellow, Brian J: 1 article (08/2011)|
|8.||Pita, Cristina: 1 article (08/2011)|
|9.||Carreira, Isabel M: 1 article (08/2011)|
|10.||Gil, Ana M: 1 article (08/2011)|
|1.||Renal Insufficiency (Renal Failure)
|2.||Body Weight (Weight, Body)
01/01/1992 - "When normalized to body weight (obese mice being 40% heavier) and to creatinine excretion (30% greater in obese mice), however, only the daily excretion of malate, 2-hydroxyglutarate, aconitate, 3-hydroxy-3-methylglutarate, oxalate, ethylmalonate, and 4-hydroxyphenylacetate were significantly greater in obese mice. "
|3.||Dehydration (Water Stress)
01/01/2002 - "PrpD also catalysed the dehydration of several other hydroxy acids but failed to hydrate cis-aconitate and related substrates containing double bonds, indicating that PrpD is not a typical aconitase but a dehydratase. "
08/03/1982 - "This enzyme, catalyzing a dehydration and rehydration of citrate, also catalyzes the elimination of HF from 3-fluorocitrate, yielding cis-aconitate and fluoride."
06/15/2006 - "The best characterized example of this family is the ubiquitous ACN (aconitase), which catalyses the dehydration of citrate to cis-aconitate, and the subsequent hydration of cis-aconitate to isocitrate. "
04/15/1992 - "Results of mutagenesis support the interpretation of the x-ray model, namely that Asp100 and His101 form an ion pair for elimination of the substrate hydroxyl and Ser642 may function as a general base for proton abstraction from citrate or isocitrate in the dehydration step and protonation of cis-aconitate in the hydration step. "
12/01/1987 - "The proton abstracted in the dehydration of [3H]citrate is transferred directly to undissociated cis-aconitate to form isocitrate without dilution, or cis-aconitate having dissociated, the tritium passes to the medium, presumably through the pool of bound protons indicated above. "
11/15/2004 - "In addition to inducing EP expression, cold shock results in the acquisition of sensitivity to micromolar concentrations of cis-aconitate and citrate by stumpy but not slender bloodstream forms. "
06/01/1998 - "In vitro differentiation of Trypanosoma brucei from the bloodstream to the procyclic form is efficiently induced by the combination of cold shock from 37 to 27 degrees C and the addition of citrate/cis-aconitate (CCA) to the incubation medium. "
11/12/1996 - "Stumpy populations emanating from these infections transformed rapidly and synchronously into dividing procyclic forms when triggered with cis-aconitate and a temperature shift. "
04/01/2008 - "pylori infection disturbs carbohydrate metabolism to elevate the levels of alpha- and beta-glucose, and cis-aconitate (a TCA cycle intermediate). "
|3.||ethylmalonic acid (ethylmalonate)
|4.||malic acid (malate)
|7.||N,N-dimethylarginine (asymmetric dimethylarginine)
|8.||Citric Acid (Citrate)
|9.||Aconitate Hydratase (Aconitase)
|10.||isocitric acid (isocitrate)
|1.||Fluid Therapy (Oral Rehydration Therapy)
|2.||Drug Therapy (Chemotherapy)