|1.||Popova, T N: 11 articles (07/2014 - 08/2002)|
|2.||Juang, Horng-Heng: 9 articles (01/2013 - 03/2004)|
|3.||Tsui, Ke-Hung: 5 articles (01/2013 - 06/2005)|
|4.||Matasova, L V: 5 articles (12/2012 - 08/2002)|
|5.||Agarkov, A A: 4 articles (05/2015 - 10/2009)|
|6.||Chang, Phei-Lang: 4 articles (01/2013 - 02/2006)|
|7.||Szweda, Luke I: 3 articles (06/2015 - 04/2005)|
|8.||Popov, S S: 3 articles (05/2015 - 08/2007)|
|9.||Zweier, Jay L: 3 articles (01/2014 - 02/2006)|
|10.||Feng, Tsui-Hsia: 3 articles (01/2013 - 06/2005)|
07/01/1988 - "Since aconitate hydratase is not a key enzyme, these unexpected data are of interest in the study of cancer biochemistry."
07/01/1988 - "Moreover, the specific activities of aconitate hydratase in both cytoplasm and mitochondria decrease when the tumor progresses in the peritoneum of BALB/C mice, as well as the percentage of aconitate hydratase activity in the presence of oxalacetate as the inhibitor. "
09/01/1986 - "Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. "
07/01/1988 - "Characterization of aconitate hydratase from mitochondria and cytoplasm of ascites tumor cells."
01/23/1987 - "Previous studies have shown that cytotoxic activated macrophages cause inhibition of DNA synthesis, of mitochondrial respiration, and of aconitase activity in tumor target cells. "
01/01/2011 - "p53 downregulates the gene expression of mitochondrial aconitase in human prostate carcinoma cells."
03/01/2004 - "Modulation of mitochondrial aconitase on the bioenergy of human prostate carcinoma cells."
01/01/2013 - "Hypoxia upregulates the gene expression of mitochondrial aconitase in prostate carcinoma cells."
08/01/2004 - "In vitro studies indicated that dihydrotestosterone (DHT) stimulates the enzymatic activity of the mitochondrial aconitase (mACON) in androgen-sensitive prostatic carcinoma cells, LNCaP. "
05/01/2006 - "To investigate the possible role of manganese in the regulation of mitochondrial aconitase (mACON) activity human prostate carcinoma cell line PC-3 cells. "
01/01/2006 - "That a relative deficiency in GSH precedes later changes in the activities of complex I and aconitase in vulnerable hippocampal sub-regions, occurring within a clinically relevant therapeutic time window, suggests that strategies to boost GSH levels and/or otherwise reduce oxidative stress following seizures, deserve further study, both in terms of preventing the biochemical consequences of SE and the neuronal dysfunction and clinical consequences."
03/01/2004 - "Before the age at which spontaneous seizures appear in a subset of the mice, Sod2(-/+) mice demonstrated increased susceptibility to behavioral seizures, mitochondrial aconitase inactivation, and neurodegeneration induced by the administration of kainate. "
01/01/2003 - "Kainate-induced seizures resulted in increased mitochondrial aconitase inactivation and 8-OHdG formation in adult (postnatal day 30 or more), but not in immature rats (postnatal days 12 and 21). "
06/01/2004 - "The data demonstrate that inhibition of aconitase in astrocytes lowers the doses of both kainic acid and pilocarpine that will cause behavioral seizures and may increase neuronal vulnerability to seizures."
03/01/2004 - "We demonstrate here that a subset of mice with partial deficiency of the mitochondrial superoxide dismutase (Sod2(-/+)) show increased incidence of spontaneous and handling-induced seizures that correlates with chronic mitochondrial oxidative stress (increased aconitase inactivation and 8-hydroxy-2'-deoxyguanosine formation in mitochondria) and diminished mitochondrial oxygen utilization. "
|4.||Muscular Diseases (Myopathy)
05/01/1995 - "Hereditary myopathy with lactic acidosis, succinate dehydrogenase and aconitase deficiency in northern Sweden: a genealogical study."
08/01/2009 - "Myopathy with deficiency of succinate dehydrogenase and aconitase is a recessively inherited disorder characterized by childhood-onset early fatigue, dyspnoea and palpitations on trivial exercise. "
03/01/2008 - "A myopathy with severe exercise intolerance and myoglobinuria has been described in patients from northern Sweden, with associated deficiencies of succinate dehydrogenase and aconitase in skeletal muscle. "
07/07/2009 - "Its critical importance has been recently underscored by the finding that a single intronic mutation in the human iscu gene is associated with a myopathy resulting from deficient succinate dehydrogenase and aconitase [Mochel, F., Knight, M. "
05/01/1995 - "A hereditary myopathy with lactic acidosis during physical exercise, low physical work capacity, and paroxysmal myoglobinuria (HML), called "Myopathy with deficiency of succinate dehydrogenase and aconitase" (McKusick 255125) has been described in 19 members of nine families who lived in two geographically separate areas in northern Sweden. "
06/01/1991 - "Conditioned medium (CM) from cultures of cytotoxic activated macrophages causes inhibition of mitochondrial respiration, DNA synthesis, and aconitase activity in murine EMT-6 mammary adenocarcinoma cells by an L-arginine dependent effector mechanism. "
07/01/1988 - "Treatment of EMT-6 mammary adenocarcinoma cells with gamma interferon (rMuIFN gamma) plus tumor necrosis factor (rMuTNF alpha) and/or interleukin-1 (rHuIL-1 alpha) causes release of iron-55 label, inhibition of DNA replication, and inhibition of aconitase activity. "
11/01/2007 - "The present study demonstrates that upon illumination, ZnTM-3-PyP inactivates glucose-6-phosphate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, lactate dehydrogenase, NADP+ -linked isocitrate dehydrogenase, aconitase, and fumarase in adenocarcinoma LS174T cells. "
|2.||Succinate Dehydrogenase (Fumarate Reductase)
|3.||Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))
|4.||Fumarate Hydratase (Fumarase)
|6.||DNA (Deoxyribonucleic Acid)
|7.||L-Lactate Dehydrogenase (Lactate Dehydrogenase)
|8.||Guanidine (Guanidine Nitrate)
|10.||Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)
|2.||Fluid Therapy (Oral Rehydration Therapy)