Achlorhydria (Hypochlorhydria)

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535 relevant articles (7 outcomes, 29 trials/studies) found for this Disease

Description: A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion.

Also Known As:

Hypochlorhydria; Achylia Gastrica

Relationship Network

Disease Context: Research Results

Digestive System Diseases: 29

Gastrointestinal Diseases: 1158

Stomach Diseases: 357

Achlorhydria: 535

Nutritional and Metabolic Diseases

Metabolic Diseases: 1264

Acid-Base Imbalance: 63

Achlorhydria: 535

Related Diseases

1.	Duodenal Ulcer (Curling's Ulcer)
2.	Gastritis
3.	Peptic Ulcer (Peptic Ulcers)
4.	Hemorrhage
5.	Dyspepsia (Indigestion)
91 Diseases and 274 more articles analyzed in the Research Interface, order at left...

Experts

1.	Kuwamura, M: 1 article (07/2008)
2.	Kuramoto, T: 1 article (07/2008)
3.	Serikawa, T: 1 article (07/2008)
4.	Yamate, J: 1 article (07/2008)
5.	Kotani, T: 1 article (07/2008)
6.	Okajima, R: 1 article (07/2008)
7.	Friis-Hansen, L: 1 article (01/2006)
8.	Rubio, Carlos A: 1 article (08/2005)
9.	Miller, Marian L: 1 article (08/2005)
10.	Shull, Gary E: 1 article (08/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Achlorhydria:

1.	GastrinsIBA 06/01/1987 - "2. Since low gastric acid secretion is a stimulus for gastrin release in mature animals the present study examined whether the relative hypochlorhydria in the sheep fetus was sustaining the hypergastrinaemia" 07/01/2007 - "Furthermore, vtg-2J/vtg-2J mice showed gastric achlorhydria associated with elevation of their serum gastrin levels" 07/01/2006 - "CONCLUSIONS: Independently of gastrin, achlorhydria is associated with gastric bacterial overgrowth and intestinal gene expression patterns and is associated with predisposition to disease" 07/01/2006 - "We also explored the associated changes in the gastric microflora and the long-term consequences of gastrin-deficient achlorhydria" 02/01/2006 - "Plasma gastrin concentrations indicative of hypochlorhydria (i.e" Get all the results and reference details, order at left...
2.	Cimetidine (Biomet)FDA LinkGeneric 02/01/2003 - "These numbers show a trend suggesting that cimetidine-induced hypochlorhydria increases shedding of viable H" 02/01/2003 - "Five of the 16 patients gave positive cultures with at least one stool from both normal pH and cimetidine-induced hypochlorhydria" 02/01/2003 - "Helicobacter pylori in cathartic stools of subjects with and without cimetidine-induced hypochlorhydria." 03/01/1985 - "Only when the dose of cimetidine infusion was doubled to 100 mg/h and administered with a constant infusion of antacid was sustained achlorhydria achieved in each patient." 08/01/1981 - "Cimetidine-induced hypochlorhydria allows bacterial proliferation in the stomach; 75 per cent of aspirates from 44 fasting patients taking cimetidine 1 g daily were found to contain bacteria 2--4 h after the last dose" Get all the results and reference details, order at left...
3.	Pepsinogen A (Pepsinogen)IBA 01/01/1991 - "In relatives with achlorhydria and low serum pepsinogen I levels the incidence of malignancy did not significantly differ from that in controls of similar age and sex distribution" 09/06/1957 - "Uropepsinogen excretion in patients with pernicious anaemia and in subjects with simple achlorhydria." 09/01/1994 - "The efficacy of this test in the diagnostic investigation of pernicious anaemia was compared with that of serum pepsinogen I. Twenty one patients with pernicious anaemia--that is, patients with achlorhydria--and 22 with healed duodenal ulcer and normal chlorhydria were studied" 11/01/1989 - "These results show that achlorhydria is frequently associated with hypergastrinemia and low pepsinogen I serum levels in patients with cirrhosis and gastric vascular ectasias and suggest that this disturbance is not secondary to a morphologic abnormality of the gastric mucosa." 04/01/1983 - "The father had hypochlorhydria and a low serum pepsinogen I/II ratio, suggesting atrophic gastritis" Get all the results and reference details, order at left...
4.	Secretin FDA Link 05/01/1988 - "Secretin test and achlorhydria." 04/01/1988 - "False-positive secretin-KABI provocation test associated with achlorhydria." 07/01/1987 - "Thus, the intravenous secretin test may be positive in patients with achlorhydria-related hypergastrinemia" 07/01/1987 - "Positive intravenous secretin test in patients with achlorhydria-related hypergastrinemia." 08/01/1986 - "Diagnosis of achlorhydria by plasma secretin determination--a tubeless approach." Get all the results and reference details, order at left...
5.	Hydrochloric Acid (Hydrogen Chloride)FDA Link 12/01/1992 - "In reduced or absent stomach acid secretion a constellation of gastrointestinal symptoms has been consistently observed and reported by clinicians in the past, and treatment of the hypochlorhydria with hydrochloric acid or its substitutes has often been observed to be effective in reducing these symptoms." 08/01/1991 - "In achlorhydria is can be used for determination of a residual capacity of the stomach to secrete the hydrochloric acid in failure of humoral stimulators." 04/02/1979 - "Hydrochloric acid treatment of achlorhydria]" 01/01/1973 - "Gastric emptying in patients with achlorhydria or hyposecretion of hydrochloric acid." 11/27/1958 - "Excretion of 5-hydroxyindoleacetic acid in achlorhydria and the effect upon it of hydrochloric acid." Get all the results and reference details, order at left...
6.	Anti-Bacterial Agents (Antibiotics)IBA 04/01/1997 - "pylori and extreme hypochlorhydria has a deleterious effect on the organism, the most likely mechanism by which antisecretory drugs as a class provide this effect is by improving the efficacy of the antibiotics themselves" 10/01/2001 - "Significant risk factors for HUS were age <15 years or >65 years (odds ratio [OR], 4.4; 95% confidence interval [CI], 1.3-14.4), hypochlorhydria (OR, 6.7; 95% CI, 1.9-24.0), and coincidental antibiotics (OR, 4.7; 95% CI 1.4-16.5)" 11/10/1998 - "Some special risk groups for which the risks could be quantified are (1) persons with underlying diseases, such as neoplasms or diabetes mellitus (1200 cases/100,000 pyar); (2) persons with achlorhydria or who excessively use antacids (1100 cases/100,000 pyar); (3) persons who have recently been treated with antibiotics that disturb the normal gut flora (1700 cases/100,000 pyar); (4) nurses (900 cases/100,000 pyar); (5) caterers (900 cases/100,000 pyar); (6) slaughterline personnel (1800 cases/100,000 pyar)" 01/01/2002 - "When omeprazole-treated mice were treated with antibiotics alone, elevated plasma gastrin levels returned to baseline and D cell numbers returned to resting levels despite persistent hypochlorhydria" Get all the results and reference details, order at left...
7.	Interleukin-1beta (Interleukin 1 beta)IBA 05/01/2007 - "IL-1 beta is a potent proinflammatory cytokine which causes a partial clearance of the organism as well as hypochlorhydria" 09/01/2005 - "BACKGROUND: Interleukin-1beta (IL-1beta) gene polymorphisms are related to hypochlorhydria and increase the risk of gastric cancer in the presence of Helicobacter pylori infection" 07/01/2002 - "Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan." Get all the results and reference details, order at left...
8.	AlkaliesIBA 03/01/1978 - "A wider group of patients than those selected in previous series may benefit from this operation, as good results can be obtained in patients with dyspepsia relieved by alkali and without achlorhydria or gastritis" Get all the results and reference details, order at left...
9.	Histamine (Histamine Dihydrochloride)IBA 08/01/1965 - "Histamine tests in the study of the genesis and characteristics of stomach achlorhydria]" 12/01/1960 - "The Kay augmented histamine test has been used in a special study of 30 patients with pernicious anaemia and 136 other subjects suspected of having achlorhydria" 03/09/1996 - "A presumptive diagnosis of pernicious anaemia was confirmed by gastric analysis which revealed a histamine fast achlorhydria" 01/01/1996 - "4. The results are consistent with a role for VMAT2 in the transport of histamine into enterochromaffin-like cell secretory vesicles, and with upregulation of the transporter to accommodate the increased histamine biosynthesis and secretion that accompanies achlorhydria." 01/01/1990 - "In this case, basal achlorhydria is associated with resistance to histamine stimulation and with high values of gastrinemia" Get all the results and reference details, order at left...
10.	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/01/2002 - "These factors are in part physiological such as the achlorhydria which affects vitamin B12 absorption and in part socioeconomic and habitual" 05/01/1999 - "Acid inhibiting agents increase achlorhydria and reduce vitamin B12 absorption" 12/01/1994 - "OBJECTIVE: To investigate the effects of hypochlorhydria and acidic drink ingestion on protein-bound vitamin B12 absorption in elderly subjects" 01/01/1986 - "Low serum vitamin B12 levels were found in 27 patients (21%) and achlorhydria in 30" 12/01/1982 - "Many of these young patients with PCA already have achlorhydria and evidence of decreased absorption of cobalamin" Get all the results and reference details, order at left...
204 Drugs and Important Bio-Agents and 513 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Gastrectomy 03/01/1994 - "Patients with achlorhydria, hypertrophic gastropathy, or after total gastrectomy fell into an aberrant category" 10/01/1957 - "Factors responsible for achlorhydria after subtotal gastrectomy.]" 08/01/1957 - "Factors responsible for achlorhydria after subtotal gastrectomy.]" 07/01/1957 - "Factors responsible for achlorhydria after subtotal gastrectomy.]" 01/01/1951 - "Post-gastrectomy achlorhydria.]" Get all the results and reference details, order at left...
2.	Vagotomy 10/01/1975 - "Ulcus duodenum and ulcus pepticum jejuni post-operativum are the domain of vagotomy, whereas in ulcus ventriculi in most cases is resected according to Billroth I. In old patients or severe concomitant diseases vagotomies--even in hypochlorhydria--yield as satisfying results as excision of ulcer and segment resections" 05/01/1992 - "In our patients with pernicious anemia, as a result of hypo or achlorhydria, serum gastrin increase was higher than in any other cause of hypochlohydria: anti-acid treatment, vagotomy.." 01/01/1975 - "Hypergastrinaemia associated with hypo-achlorhydria occurs in atrophic gastritis without extensive antral lesion and after vagotomy" 01/01/1993 - "In our patients with pernicious anemia, as a result of hypo or achlorhydria, serum gastrin increase was higher than in any other cause of hypochlorhydria: anti-acid treatment, vagotomy .." 02/01/1989 - "Basal serum gastrin (mean +/- SEM) was progressively higher for each group; normal (42 +/- 3 pg/ml), duodenal ulcer (53 +/- 4 pg/ml), vagotomy (226 +/- 54 pg/ml), hypochlorhydria (346 +/- 92 pg/ml), achlorhydria (844 +/- 100 pg/ml)" Get all the results and reference details, order at left...
3.	Transplants (Transplant) 12/07/1979 - "33 transplant candidates of groups I (hypochlorhydria, no ulcer) and II (normochlorhydria, no ulcer) were treated by medical prophylaxis alone" 08/01/1963 - "ZOLLINGER-ELLISON SYNDROME: SURGICAL REMOVAL OF PARIETAL CELL MASS WITH PRESERVATION OF ANTRUM AND PYLORUS, ILEOCOLONIC TRANSPLANT AND RESULTANT ACHLORHYDRIA." Get all the results and reference details, order at left...
4.	Gastroenterostomy 10/01/1975 - "Ulcus duodenum and ulcus pepticum jejuni post-operativum are the domain of vagotomy, whereas in ulcus ventriculi in most cases is resected according to Billroth I. In old patients or severe concomitant diseases vagotomies--even in hypochlorhydria--yield as satisfying results as excision of ulcer and segment resections" 09/01/1985 - "Sixteen patients with pentagastrin-fast achlorhydria and 12 patients who had undergone Billroth II gastrectomy (at least 3 years previously) were compared with 10 acid-secreting volunteers and 13 patients with endoscopically proven peptic disease" Get all the results and reference details, order at left...
5.	Drug Therapy (Chemotherapy) 01/01/2008 - "Control of infection classically involves hand and healthcare hygiene, reduction of selective and ineffective chemotherapy, reduction of invasive procedures and achlorhydria and adequate staffing, along with appropriate containment and concentration of patients" 11/01/1992 - "It has been proposed that the generation of luminal hypo- or achlorhydria by powerful acid inhibitory pharmacotherapy may result in hypergastrinemia" Get all the results and reference details, order at left...
16 Therapies and Procedures and 41 more articles analyzed in the Research Interface, order at left...

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