|1.||Yang, Xiang-Jiao: 3 articles (02/2012 - 01/2004)|
|2.||Hein, David W: 3 articles (01/2010 - 03/2003)|
|3.||Valor, Luis M: 2 articles (01/2014 - 01/2013)|
|4.||Lopez-Atalaya, Jose P: 2 articles (01/2014 - 01/2013)|
|5.||Barco, Angel: 2 articles (01/2014 - 01/2013)|
|6.||Han, Qian: 2 articles (07/2012 - 09/2011)|
|7.||Christensen, Bruce M: 2 articles (07/2012 - 09/2011)|
|8.||Li, Jianyong: 2 articles (07/2012 - 09/2011)|
|9.||Zhao, Ping: 2 articles (03/2010 - 01/2010)|
|10.||Han, Xuesong: 2 articles (03/2010 - 01/2010)|
01/01/2015 - "Accumulating evidence indicates that Nα-terminal acetyltransferases (NATs), that are dysregulated in numerous human cancers, can serve as therapeutic targets. "
10/01/2014 - "The human N-acetyltransferase Ard1 (hArd1) is one of the acetyltransferases that has been found to be overexpressed in various cancer cells and tissues, and knockout of the hArd1 gene significantly reduces growth rate of the cancer cell lines. "
01/17/2013 - "Protein N-terminal acetyltransferases in cancer."
02/01/2012 - "These results demonstrate the importance of ING association with MYST acetyltransferases in controlling cell proliferation, a regulated link that accounts for the reported tumor suppressor activities of these complexes."
07/01/2008 - "Polymorphisms of human N-acetyltransferases and cancer risk."
|2.||Breast Neoplasms (Breast Cancer)
05/01/1998 - "Cigarette smoking, N-acetyltransferases 1 and 2, and breast cancer risk."
01/01/2006 - "In this study, arylamine N-acetyltransferases, NATs (E.C.126.96.36.199) and glutathione-S-transferase-T2-2, GSTT2-2 (E.C.188.8.131.52) enzyme activities in the breast tumor and surrounding tumor-free tissues of 22 female breast cancer patients with infiltrating ductal carcinoma were measured. "
04/25/2002 - "This study examined the possible effect of cytochrome P450 (CYP1A1), glutathione S-transferase (GSTM1 and T1) and N-acetyltransferases 2 (NAT2) polymorphisms on DNA-protein crosslinks (DPC) formation in the white blood cells of breast cancer patients, and assessed the levels of DPC detected. "
04/15/2001 - "Since individuals with modified ability to metabolize these carcinogens could have a different risk for breast cancer, we investigated the role of cytochromes P-450 (CYP1A1, CYP2D6), glutathione-S-transferases (GSTM1, GSTT1, GSTP1) and N-acetyltransferases (NAT1, NAT2) gene variants in breast carcinogenesis. "
|3.||Lung Neoplasms (Lung Cancer)
04/01/2009 - "Studies have linked the polymorphisms in N-acetyltransferases (NAT2), a key enzyme for metabolism of hydrocarbons, with lung cancer in Asian female nonsmokers. "
07/01/2010 - "Polymorphism of cytochrome p450, glutathione-s-transferase and N-acetyltransferases: influence on lung cancer susceptibility."
07/01/2010 - "Many studies have focused on the relation between the distribution of polymorphic variants of different forms of the metabolic enzymes and lung cancer susceptibility, Few of human biotransformating enzymes (Phase I enzyme: Cytochrome p450 enzymes, and Phase II enzymes: Glutathione-s-transferases, N-acetyltransferases) have been implicated in the formation and scavenging of ultimate reactive metabolites. "
|4.||Non-Hodgkin Lymphoma (Lymphosarcoma)
01/01/2010 - "Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma."
03/01/2010 - "The aim of this study was to investigate whether genetic polymorphisms in cytochrome P450s (CYPs), glutathione S-transferases (GSTs), and N-acetyltransferases (NATs) genes modify the relationship between alcohol consumption and risk of non-Hodgkin's lymphoma (NHL) in a population-based, case-control study including 1,115 Connecticut women. "
|5.||Alzheimer Disease (Alzheimer's Disease)
12/04/1995 - "In this study, enzyme activities previously investigated in Alzheimer's disease (peptidases, dehydrogenases and acetyltransferases) were measured in the septum and hippocampus of control and streptozotocin-treated rats. "
03/09/2012 - "The cellular levels of β-site APP cleaving enzyme 1 (BACE1), the rate-limiting enzyme for the generation of the Alzheimer disease (AD) amyloid β-peptide (Aβ), are tightly regulated by two ER-based acetyl-CoA:lysine acetyltransferases, ATase1 and ATase2. "
|2.||Glutathione (Reduced Glutathione)
|4.||Cytochrome P-450 Enzyme System (Cytochrome P450)
|6.||Cytochrome P-450 CYP1A1 (CYP1A1)
|9.||Histone Deacetylases (Histone Deacetylase)
|10.||Glutathione Transferase (Glutathione S-Transferase)