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Acetyl-CoA Carboxylase

A carboxylating enzyme that catalyzes the conversion of ATP, acetyl-CoA, and HCO3- to ADP, orthophosphate, and malonyl-CoA. It is a biotinyl-protein that also catalyzes transcarboxylation. The plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA (From Enzyme Nomenclature, 1992) EC 6.4.1.2.
Also Known As:
Acetyl CoA Carboxylase; Carboxylase, Acetyl-CoA; Acetyl Coenzyme A Carboxylase; Acetyl-CoA:carbon-dioxide ligase (ADP-forming)
Networked: 530 relevant articles (21 outcomes, 34 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Steinberg, Gregory R: 7 articles (01/2022 - 08/2006)
2. Harwood, H James: 7 articles (01/2019 - 09/2003)
3. Kemp, Bruce E: 6 articles (11/2021 - 08/2006)
4. Freedman, Barry I: 5 articles (05/2022 - 02/2010)
5. Esler, William P: 5 articles (10/2020 - 12/2014)
6. Cao, Deliang: 5 articles (11/2011 - 02/2008)
7. Houde, Vanessa P: 4 articles (11/2021 - 07/2015)
8. Müller, Rolf: 4 articles (10/2021 - 01/2018)
9. Swinnen, Johannes V: 4 articles (10/2021 - 08/2005)
10. Li, Xiaobing: 4 articles (08/2019 - 10/2018)

Related Diseases

1. Insulin Resistance
2. Fibrosis (Cirrhosis)
3. Non-alcoholic Fatty Liver Disease
4. Obesity
5. Fatty Liver

Related Drugs and Biologics

1. Fatty Acid Synthases (Fatty Acid Synthase)
2. AMP-Activated Protein Kinases
3. Messenger RNA (mRNA)
4. Adenosine Monophosphate (AMP)
5. Glucose (Dextrose)
6. Peroxisome Proliferator-Activated Receptors (PPAR)
7. Phosphoenolpyruvate
8. Fatty Acids (Saturated Fatty Acids)
9. Proteins (Proteins, Gene)
10. Lipids

Related Therapies and Procedures

1. Therapeutics
2. Castration
3. Aftercare (After-Treatment)
4. Ketogenic Diet
5. Fat-Restricted Diet (Diet, Fat Restricted)