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Calcimycin (A23187)

An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
Also Known As:
A23187; A-23187; Antibiotic A23187; A 23187; A23187, Antibiotic; 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-
Networked: 752 relevant articles (5 outcomes, 48 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wang, Qi: 4 articles (10/2011 - 07/2007)
2. Mizushina, Yoshiyuki: 3 articles (06/2015 - 11/2012)
3. Kuriyama, Isoko: 3 articles (06/2015 - 11/2012)
4. Kobayashi, Yuko: 3 articles (06/2014 - 01/2012)
5. Jippo, Tomoko: 3 articles (06/2014 - 01/2012)
6. Nakayama, Hiroto: 2 articles (06/2014 - 11/2012)
7. Mitoshi, Mai: 2 articles (06/2014 - 11/2012)
8. Yoshida, Hiromi: 2 articles (06/2014 - 11/2012)
9. Sugimoto, Keiichiro: 2 articles (06/2014 - 11/2012)
10. Miyazato, Hironari: 2 articles (06/2014 - 11/2012)

Related Diseases

1. Neoplasms (Cancer)
2. Anoxia (Hypoxia)
3. Lung Neoplasms (Lung Cancer)
4. Pleurisy (Pleuritis)
5. Asthma (Bronchial Asthma)

Related Drugs and Biologics

1. Calcium
2. phorbol
3. Carrageenan
4. anti-IgE
5. Etoposide (VP 16)
6. Egtazic Acid (EGTA)
7. Epidermal Growth Factor (EGF)
8. Nerve Growth Factor (NGF)
9. L 663536
10. Arachidonic Acid (Vitamin F)

Related Therapies and Procedures

1. Lenses
2. Aftercare (After-Treatment)
3. Ligation
4. Transplants (Transplant)
5. Parathyroidectomy