8a- methyl- 1,3- dioxo- 2- (2- phenylcyclopropyl)- N- (1- phenyl- 1H- pyrazol- 5- yl)hexahydroimidazo(1,5- a)pyrazine- 7(1H)- carboxamide
a smoothened antagonist; structure in first source
Also Known As:
MK 5710; MK-5710; MK5710
Networked: 2
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Altamura, Sergio:
2 articles
(08/2011 - 08/2011)
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2. | Filocamo, Gessica:
2 articles
(08/2011 - 08/2011)
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3. | Hernando, Jose Ignacio Martin:
2 articles
(08/2011 - 08/2011)
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4. | Jones, Philip:
2 articles
(08/2011 - 08/2011)
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5. | Kinzel, Olaf:
2 articles
(08/2011 - 08/2011)
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6. | Malancona, Savina:
2 articles
(08/2011 - 08/2011)
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7. | Rowley, Michael:
2 articles
(08/2011 - 08/2011)
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8. | Scarpelli, Rita:
2 articles
(08/2011 - 08/2011)
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9. | Steinkühler, Christian:
2 articles
(08/2011 - 08/2011)
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10. | Alfieri, Anna:
1 article
(08/2011)
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Related Diseases
1. | Neoplasms (Cancer)
08/01/2011
- " Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydroimid azo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, part 1." 08/01/2011
- " Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclo- propyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydro-imidazo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, part 2."
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