HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

N- 4,4- dimethyl- 2- thioxo- 1,4- dihydro- 2H- 3,1- benzoxazin- 6- ylthiophene- 2- sulfonamide

structure in first source

Also Known As:

SM 368229; SM-368229; SM368229

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - N-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-ylthiophene-2-sulfonamide: 2
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - N-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-ylthiophene-2-sulfonamide: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - Benzoxazines: 58
      - N-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-ylthiophene-2-sulfonamide: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzoxazines: 58
      - N-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-ylthiophene-2-sulfonamide: 2

Experts

1.	Fujita, Katsuya: 2 articles (01/2012 - 01/2011)
2.	Hori, Seiji: 2 articles (01/2012 - 01/2011)
3.	Katayama, Seiji: 2 articles (01/2012 - 01/2011)
4.	Matsui, Kazuki: 2 articles (01/2012 - 01/2011)
5.	Mori, Masaya: 2 articles (01/2012 - 01/2011)
6.	Nariai, Tetsuro: 2 articles (01/2012 - 01/2011)

Related Diseases

1.	Hypertension (High Blood Pressure) 01/01/2011 - "These findings indicate that SM-368229 may offer a new promising therapeutic option for the treatment of hypertension and heart failure." 01/01/2012 - "These results clearly demonstrated that SM-368229 strongly attenuated the progression of hypertension and exerted cardiorenal protection in aldosterone/salt-treated hypertensive rats."
2.	Heart Failure 01/01/2011 - "These findings indicate that SM-368229 may offer a new promising therapeutic option for the treatment of hypertension and heart failure."
3.	Fibrosis (Cirrhosis) 01/01/2012 - "In real-time polymerase chain reaction analysis, SM-368229 abolished aldosterone-induced gene expression levels for inflammatory, fibrosis and oxidative stress markers in hearts and kidneys. "

Related Drugs and Biologics

1.	Salts
2.	Aldosterone