ERW1227B

06/01/2011 - "The above findings identify ERW1227B as a potential novel therapeutic agent in the treatment of glioblastomas."
06/01/2011 - "Bioassays as well as time-lapse photography of glioblastoma cells treated with ERW1227B showed cell death and rapid loss of cellular motility. "
06/01/2011 - "Novel chemo-sensitizing agent, ERW1227B, impairs cellular motility and enhances cell death in glioblastomas."
06/01/2011 - "Treatment of glioblastoma cells with ERW1227B was associated with both down-regulation of the PI-3 kinase/Akt pathway, which enhanced cell death; as well as disruption of focal adhesive complexes and intracellular actin fibers, which impaired cellular mobility. "
06/01/2011 - "Mice studies with in vivo glioblastoma models demonstrated the ability of ERW1227B to sensitize tumor cells to cell death after treatment with either chemotherapy or radiation. "

06/01/2011 - "Mice studies with in vivo glioblastoma models demonstrated the ability of ERW1227B to sensitize tumor cells to cell death after treatment with either chemotherapy or radiation. "