Insulin FDA Link

A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).

Also Known As:

Novolin; Iletin; Insulin A Chain; Insulin B Chain; Insulin, Regular; Sodium Insulin; Soluble Insulin; Chain, Insulin B; Insulin, Sodium; Insulin, Soluble; Regular Insulin

Pharmalogical Action Categories:

Hypoglycemic Agents

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Pancreatic Hormones: 113
      - Insulins: 644
        Proinsulin: 1195
        Insulin: 113363
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Hormones: 1347
    - Pancreatic Hormones: 113
      - Insulins: 644
        Proinsulin: 1195
        Insulin: 113363

1.	Diabetes Mellitus 11/01/1949 - "Experiences in the clinical use of globin zinc insulin in the treatment of diabetes mellitus."

Globin Zinc Insulin

Bio-Agent Context: Research Results

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