|1.||Sowa, Yoshihiro: 2 articles (08/2010 - 11/2007)|
|2.||Sakai, Toshiyuki: 2 articles (08/2010 - 11/2007)|
|3.||Matsui, Taka-Aki: 1 article (08/2010)|
|4.||Kubo, Toshikazu: 1 article (08/2010)|
|5.||Murata, Hiroaki: 1 article (08/2010)|
|6.||Horie, Naoyuki: 1 article (08/2010)|
|7.||Tsuji, Yoshiro: 1 article (08/2010)|
|8.||Koto, Kazutaka: 1 article (08/2010)|
|9.||Sakabe, Tomoya: 1 article (08/2010)|
|10.||Nanayama, Toyomichi: 1 article (11/2007)|
08/01/2010 - "In this study, we investigated the antitumor activity of JTP-70902, a novel specific MEK inhibitor, against human fibrosarcoma cells in which the ERK pathway is constitutively activated. "
08/01/2010 - "Our results showed that JTP-70902 inhibits cell growth and induces cell cycle arrest in human Ras mutant fibrosarcoma cells. "
08/01/2010 - "These results indicate that JTP-70902 might be an attractive compound for molecular-targeting chemotherapy for malignant soft tissue tumors with the activation of the Ras-MEK-ERK pathway."
11/01/2007 - "JTP-70902 suppressed the growth of most colorectal and some other cancer cell lines in vitro, and showed antitumor activity in an HT-29 xenograft model. "
|3.||Colonic Neoplasms (Colon Cancer)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)