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AD 6048

a blonanserin metabolite; structure in first source

Also Known As:

AD-6048; AD6048

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - AD 6048: 3
  - Piperazines: 26
    - AD 6048: 3

Experts

1.	Ohno, Yukihiro: 3 articles (11/2015 - 08/2010)
2.	Shimizu, Saki: 3 articles (11/2015 - 08/2010)
3.	Tatara, Ayaka: 3 articles (11/2015 - 08/2010)
4.	Masui, Atsushi: 1 article (11/2015)
5.	Minamimoto, Shoko: 1 article (11/2015)
6.	Mizobe, Yusuke: 1 article (11/2015)
7.	Mizuguchi, Yuto: 1 article (11/2015)
8.	Ochiai, Midori: 1 article (11/2015)
9.	Tamura, Miyuki: 1 article (11/2015)
10.	Andatsu, Saki: 1 article (04/2014)

Related Diseases

1.	Catalepsy 11/01/2015 - "AD-6048 did not cause extrapyramidal side effects (EPS) even at high doses (up to 10mg/kg, s.c.), whereas HAL at doses of 0.1-3mg/kg (s.c.) significantly induced bradykinesia and catalepsy in a dose-dependent manner. " 08/01/2010 - "Furthermore, combined treatment of AD-6048 (0.1-3mg/kg, s.c.) with haloperidol (0.5mg/kg, i.p.) significantly attenuated haloperidol-induced bradykinesia and catalepsy. " 04/03/2014 - "In addition, U-99194A and AD-6048 per se significantly alleviated catalepsy induced by a high dose (0.5mg/kg) of haloperidol. " 04/03/2014 - "U-99194A (a selective D(3) antagonist) or AD-6048 (a preferential D(3) vs. D(2) antagonist) antagonized both the catalepsy enhancement and the locomotor inhibition with 7-OH-DPAT. "
2.	Hypokinesia (Bradykinesia) 11/01/2015 - "AD-6048 did not cause extrapyramidal side effects (EPS) even at high doses (up to 10mg/kg, s.c.), whereas HAL at doses of 0.1-3mg/kg (s.c.) significantly induced bradykinesia and catalepsy in a dose-dependent manner. " 08/01/2010 - "Furthermore, combined treatment of AD-6048 (0.1-3mg/kg, s.c.) with haloperidol (0.5mg/kg, i.p.) significantly attenuated haloperidol-induced bradykinesia and catalepsy. "

Related Drugs and Biologics

1.	Haloperidol (Haldol)
2.	(5,6-dimethoxyindan-2-yl)dipropylamine
3.	7-hydroxy-2-N,N-dipropylaminotetralin