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9- fluoro- 11,17,21- trihydroxy- 16- methylpregna- 1,4- diene- 3,20- dione 21-cyclohexanecarboxylate 17-cyclopropanecarboxylate

an anti-inflammatory corticosteroid with anti-allergic activity; structure in first source

Also Known As:

NS 126; NS-126; NS126 cpd

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Pregnenediones
        9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-cyclohexanecarboxylate 17-cyclopropanecarboxylate: 1

Experts

1.	Hashimoto, Mikiko: 1 article (01/2010)
2.	Hashino, Asami: 1 article (01/2010)
3.	Inoue, Naoki: 1 article (01/2010)
4.	Kageyama, Kiyoto: 1 article (01/2010)
5.	Kawakita, Naoko: 1 article (01/2010)
6.	Kyoi, Takashi: 1 article (01/2010)
7.	Mori, Kazuya: 1 article (01/2010)
8.	Sasagawa, Takahiro: 1 article (01/2010)
9.	Takahashi, Yosuke: 1 article (01/2010)
10.	Yoshida, Katsumi: 1 article (01/2010)

Related Diseases

1.	Allergic Rhinitis 01/01/2010 - "NS-126 is a long-acting intranasal corticosteroid and a promising therapeutic agent for allergic rhinitis." 01/01/2010 - "Pharmacological profile of the novel anti-inflammatory corticosteroid NS-126, a therapeutic agent for allergic rhinitis." 01/01/2010 - "In the allergic rhinitis model, NS-126 and FP reduced sneezing and nasal obstruction to similar extents. " 01/01/2010 - "We compared NS-126 and the widely used intranasal corticosteroid fluticasone propionate (FP) in a guinea-pig model of allergic rhinitis and a rat model of airway eosinophilia. "
2.	Nasal Obstruction 01/01/2010 - "In the allergic rhinitis model, NS-126 and FP reduced sneezing and nasal obstruction to similar extents. "
3.	Sneezing 01/01/2010 - "In the allergic rhinitis model, NS-126 and FP reduced sneezing and nasal obstruction to similar extents. "
4.	Eosinophilia 01/01/2010 - "In the airway eosinophilia model, both compounds inhibited the infiltration of eosinophils into the bronchoalveolar lavage fluid, but the effect of NS-126 was longer-lasting than that of FP. " 01/01/2010 - "We compared NS-126 and the widely used intranasal corticosteroid fluticasone propionate (FP) in a guinea-pig model of allergic rhinitis and a rat model of airway eosinophilia. "

Related Drugs and Biologics

1.	Adrenal Cortex Hormones (Corticosteroids)
2.	Fluticasone (Cutivate)