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4- (4- methoxyphenyl)- 5- (3,4,5- trimethoxyphenyl)- 1H- pyrazol- 3- amine

a tubulin polymerization inhibitor and potential antineoplastic agent; structure in first source

Also Known As:

XN 0502; XN-0502; XN0502

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	He, Qiaojun: 1 article (08/2010)
2.	Hu, Yongzhou: 1 article (08/2010)
3.	Xue, Na: 1 article (08/2010)
4.	Yang, Bo: 1 article (08/2010)
5.	Zhang, Jun: 1 article (08/2010)
6.	Zhu, Hong: 1 article (08/2010)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2010 - "Taken together, the current study demonstrates that the novel CA-4 analogue XN0502 is a promising anti-cancer agent with potent G2/M arrest- and apoptotic-inducing activities via targeting tubulin deserving further research and development, and helps provide data for exploiting new CA-4 analogues."
2.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/01/2010 - "XN0502 is characterized by its more potent anti-proliferative activities against non-small cell lung cancer A549 cells (IC(50): 1.8 +/- 0.6 microM), than that on the normal human liver HL-7702 cells (IC(50): 9.1 +/- 0.4 microM). "

Related Drugs and Biologics

1.	Tubulin