Transient Receptor Potential Channels

A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.

Also Known As:

TRP Cation Channels; TRP Membrane Proteins; Transient Receptor Potential Cation Channels; Cation Channel, TRP; Cation Channels, TRP; Channel, TRP Cation; Channels, TRP Cation; Membrane Proteins, TRP; Proteins, TRP Membrane; TRP Cation Channel; Transient Receptor Potential Cation Channel; Transient Receptor Potential Channel

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Membrane Transport Proteins: 589
      - Ion Channels: 6731
        Transient Receptor Potential Channels: 706
  - Membrane Proteins: 10078
    - Membrane Transport Proteins: 589
      - Ion Channels: 6731
        Transient Receptor Potential Channels: 706

Drosophila TRPM protein

Bio-Agent Context: Research Results