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euphorbiasteroid

may reverse multidrug resistance; a phytogenic antineoplastic agent; isolated from Euphorbia lathyris; structure in first source

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - euphorbiasteroid: 4
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylacetates: 3
      - euphorbiasteroid: 4

Experts

1.	Ahn, Kwang Seok: 1 article (06/2022)
2.	Alharbi, Sulaiman Ali: 1 article (06/2022)
3.	Chinnathambi, Arunachalam: 1 article (06/2022)
4.	Kim, Na Young: 1 article (06/2022)
5.	Mohan, Chakrabhavi Dhananjaya: 1 article (06/2022)
6.	Rangappa, Kanchugarakoppal S: 1 article (06/2022)
7.	Sethi, Gautam: 1 article (06/2022)
8.	Choi, Jung Sook: 1 article (07/2010)
9.	Kang, Nam Sook: 1 article (07/2010)
10.	Kim, Seong Hwan: 1 article (07/2010)

Related Diseases

1.	Sarcoma (Soft Tissue Sarcoma) 07/01/2010 - "In this study, we evaluated whether euphorbiasteroid isolated from Euphorbia lathyris has the potential to reverse P-glycoprotein (P-gp)-mediated multi-drug resistance (MDR) by using the drug-sensitive human sarcoma cell line MES-SA and its MDR counterpart MES-SA/Dx5. " 07/01/2010 - "Euphorbiasteroid reverses P-glycoprotein-mediated multi-drug resistance in human sarcoma cell line MES-SA/Dx5." 09/05/2023 - "Euphorbiasteroid (EPBS) has gained attention for its activity against human lung cancer and sarcoma; however, its impact on hepatocellular carcinoma has not yet been elucidated. "
2.	Obesity 09/02/2022 - "Euphorbiasteroid, a lathyrane-type diterpene from Euphorbiae semen (the seeds of Euphorbia lathyris L.), has been shown to have a variety of pharmacological effects such as anti-tumor and anti-obesity. "
3.	Neoplasms (Cancer) 09/02/2022 - "Euphorbiasteroid, a lathyrane-type diterpene from Euphorbiae semen (the seeds of Euphorbia lathyris L.), has been shown to have a variety of pharmacological effects such as anti-tumor and anti-obesity. "
4.	Lung Neoplasms (Lung Cancer) 09/05/2023 - "Euphorbiasteroid (EPBS) has gained attention for its activity against human lung cancer and sarcoma; however, its impact on hepatocellular carcinoma has not yet been elucidated. "
5.	Hepatocellular Carcinoma (Hepatoma) 09/05/2023 - "Euphorbiasteroid Induces Apoptosis as Well as Autophagy through Modulating SHP-1/STAT3 Pathway in Hepatocellular Carcinoma Cells." 09/05/2023 - "Euphorbiasteroid (EPBS) has gained attention for its activity against human lung cancer and sarcoma; however, its impact on hepatocellular carcinoma has not yet been elucidated. "

Related Drugs and Biologics

1.	Member 1 Subfamily B ATP Binding Cassette Transporter
2.	Catenins
3.	Diterpenes
4.	lathyrane