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ARQ 197

an oral small-molecule inhibitor of c-Met for the treatment of solid tumors
Also Known As:
(-)-trans-3-(5,6-dihydro-4H-pyrrolo(3,2,1-ij)quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidin-2,5-dione; ARQ-197; ARQ197; tivantinib
Networked: 106 relevant articles (14 outcomes, 54 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Schwartz, Brian: 15 articles (01/2019 - 01/2011)
2. Santoro, Armando: 11 articles (01/2019 - 01/2013)
3. Abbadessa, Giovanni: 9 articles (01/2018 - 12/2011)
4. Rimassa, Lorenza: 8 articles (01/2019 - 01/2013)
5. Porta, Camillo: 7 articles (01/2018 - 01/2013)
6. Chai, Feng: 6 articles (01/2018 - 04/2011)
7. Daniele, Bruno: 6 articles (01/2018 - 01/2013)
8. Trojan, Jörg: 6 articles (01/2018 - 01/2013)
9. Personeni, Nicola: 5 articles (01/2018 - 01/2013)
10. Shuster, Dale: 5 articles (01/2018 - 08/2015)

Related Diseases

1. Hepatocellular Carcinoma (Hepatoma)
2. Neoplasms (Cancer)
3. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
4. Lung Neoplasms (Lung Cancer)
5. Adenocarcinoma

Related Drugs and Biologics

1. ARQ 197
2. Erlotinib Hydrochloride (CP 358,774)
3. Sorafenib (BAY 43-9006)
4. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
5. 1- (4- ((2- (2- aminopyrimidin- 5- yl)- 7- methyl- 4- morpholinothieno(3,2- d)pyrimidin- 6- yl)methyl)piperazin- 1- yl)- 2- hydroxypropan- 1- one
6. dactolisib
7. Phosphotransferases (Kinase)
8. Afatinib
9. 5- ((2,6- dichlorobenzyl)sulfonyl)- 3- ((3,5- dimethyl- 4- ((2- (pyrrolidin- 1- ylmethyl)pyrrolidin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- 1,3- dihydro- 2H- indol- 2- one
10. JNJ38877605

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Castration
4. Oral Administration