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ARQ 197

an oral small-molecule inhibitor of c-Met for the treatment of solid tumors
Also Known As:
(-)-trans-3-(5,6-dihydro-4H-pyrrolo(3,2,1-ij)quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidin-2,5-dione; ARQ-197; ARQ197
Networked: 25 relevant articles (4 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Schwartz, Brian: 7 articles (08/2015 - 01/2011)
2. Abbadessa, Giovanni: 3 articles (01/2013 - 12/2011)
3. Waghorne, Carol: 3 articles (12/2012 - 04/2011)
4. Chai, Feng: 3 articles (12/2012 - 04/2011)
5. France, Dennis S: 3 articles (01/2012 - 06/2010)
6. Hirashima, T: 2 articles (10/2015 - 06/2013)
7. Akinaga, S: 2 articles (10/2015 - 06/2013)
8. Takahashi, T: 2 articles (10/2015 - 06/2013)
9. Yamamoto, N: 2 articles (10/2015 - 06/2013)
10. Sequist, Lecia V: 2 articles (08/2015 - 09/2012)

Related Diseases

1. Neoplasms (Cancer)
2. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
3. Lung Neoplasms (Lung Cancer)
4. Mesothelioma
5. Hepatocellular Carcinoma (Hepatoma)

Related Drugs and Biologics

1. erlotinib (CP 358,774)
2. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
3. NVP BEZ235
4. Phosphotransferases (Kinase)
5. BIBW 2992
6. gemcitabine
7. Microphthalmia-Associated Transcription Factor
8. Adenosine Triphosphate (ATP)
9. cetuximab (Erbitux)
10. Epidermal Growth Factor Receptor (EGF Receptor)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Oral Administration