oncocin

01/01/1987 - "ONCOCIN is an expert system that provides advice to physicians who are treating cancer patients enrolled in clinical trials. "
10/01/1985 - "Physicians use the system, termed ONCOCIN, to record data during patient visits and to receive advice about treatment and tests required by experimental cancer protocols. "
02/01/1993 - "ONCOCIN provides therapy advice for patients on complex cancer therapy protocols based on a description of the patient's current medical status and laboratory-test values. "
01/01/1989 - "This paper presents a description of a system called ScriptGen that generates test data for validating the knowledge base of the ONCOCIN cancer therapy planning system. "
06/01/1987 - "Through our experience with the ONCOCIN cancer therapy consultation system, we have identified a set of medical planning problems to which no single existing computer-based reasoning technique readily applies. "

10/01/2012 - "Furthermore, the tested oncocin and apidaecin derivatives do not modulate the immune response after LPS stimulation, whereas CRAMP shows a reduction of the LPS-mediated immune response as expected. "
01/01/2016 - "Synergistic effects between lytic murine cathelicidin-related AMP (CRAMP) and apidaecin- and oncocin-derivatives were studied in chequerboard assays. "
10/01/2012 - "Therefore, we studied oncocin and apidaecin derivatives for their effects on murine dendritic cells (DC) and macrophages and compared them with well-known immunomodulatory activities of murine cathelicidin-related antimicrobial peptide (CRAMP). "

11/01/2015 - "Oncocin Onc72 is highly active against Gram-negative bacteria in vitro and in vivo protecting mice in systemic infection models with Escherichia coli and KPC-producing Klebsiella pneumoniae. "
10/01/2012 - "Oncocin derivative Onc72 is highly active against Escherichia coli in a systemic septicaemia infection mouse model."
11/01/2015 - "Oncocin Onc72 is efficacious against antibiotic-susceptible Klebsiella pneumoniae ATCC 43816 in a murine thigh infection model."

12/01/1985 - "Our results show that ONCOCIN provides advice on lymphoma treatment similar to the treatment provided in a university oncology clinic."
12/01/1985 - "In a blinded evaluation, four experts on lymphoma failed to find a significant difference between the treatments selected by physicians and those proposed by ONCOCIN. "
12/01/1985 - "We compared the chemotherapy administered by clinic physicians with the treatment that would have been recommended by ONCOCIN in 415 visits for 39 patients with lymphoma seen before the program's introduction. "

11/01/2015 - "After 75 min oncocin Onc72 or the antibiotic comparator meropenem were administered subcutaneously with 100 mg (43 µmol) and 25 mg (65 µmol) per kg of body weight, respectively, six times every 75 min. "