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mayamycin

cytotoxic; from a Streptomyces strain isolated from the marine sponge Halichondria panicea; structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Benz(a)Anthracenes: 2
        mayamycin: 3
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Benz(a)Anthracenes: 2
    - mayamycin: 3

Experts

1.	Kolympadi Markovic, Maria: 1 article (02/2022)
2.	Marković, Dean: 1 article (02/2022)
3.	Matulja, Dario: 1 article (02/2022)
4.	Pavelić, Sandra Kraljević: 1 article (02/2022)
5.	Vranješević, Filip: 1 article (02/2022)
6.	Indraningrat, Anak Agung Gede: 1 article (05/2016)
7.	Sipkema, Detmer: 1 article (05/2016)
8.	Smidt, Hauke: 1 article (05/2016)
9.	Erhard, Arlette: 1 article (07/2010)
10.	Imhoff, Johannes F: 1 article (07/2010)

Related Diseases

1.	Neoplasms (Cancer) 02/21/2022 - "Presented phenolic compounds inhibited cancer cells proliferation or migration, at sub-micromolar or nanomolar concentrations (lamellarins D (37), M (38), K (39), aspergiolide B (41), fradimycin B (62), makulavamine J (66), mayamycin (69), N-acetyl-N-demethylmayamycin (70) or norhierridin B (75)). " 07/23/2010 - "Mayamycin (1) exhibited potent cytotoxic activity against eight human cancer cell lines and showed activity against several bacteria including antibiotic-resistant strains."
2.	Human Influenza (Influenza) 05/02/2016 - "Based on in vitro activity tests, identified targets of potent antimicrobial substances derived from sponge-associated microbes include: human immunodeficiency virus 1 (HIV-1) (2-undecyl-4-quinolone, sorbicillactone A and chartarutine B); influenza A (H1N1) virus (truncateol M); nosocomial Gram positive bacteria (thiopeptide YM-266183, YM-266184, mayamycin and kocurin); Escherichia coli (sydonic acid), Chlamydia trachomatis (naphthacene glycoside SF2446A2); Plasmodium spp. (manzamine A and quinolone 1); Leishmania donovani (manzamine A and valinomycin); Trypanosoma brucei (valinomycin and staurosporine); Candida albicans and dermatophytic fungi (saadamycin, 5,7-dimethoxy-4-p-methoxylphenylcoumarin and YM-202204). "

Related Drugs and Biologics

1.	4-Quinolones (4 Quinolones)
2.	Staurosporine
3.	Quinolones
4.	Valinomycin
5.	Glycosides
6.	Anti-Bacterial Agents (Antibiotics)
7.	Acids
8.	kocurin
9.	sorbicillactone A
10.	naphthacene (tetracene)