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CP 4200

an antineoplastic antimetabolite; structure in first source

Also Known As:

CP-4200; CP4200

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hals, Petter-Arnt: 2 articles (09/2013 - 05/2010)
2.	Lyko, Frank: 2 articles (09/2013 - 05/2010)
3.	Rius, Maria: 2 articles (09/2013 - 05/2010)
4.	Sandvold, Marit Liland: 2 articles (09/2013 - 05/2010)
5.	Hascher, Antje: 1 article (09/2013)
6.	Hummel-Eisenbeiss, Johanna: 1 article (09/2013)
7.	Müller-Tidow, Carsten: 1 article (09/2013)
8.	Brueckner, Bodo: 1 article (05/2010)
9.	Fichtner, Iduna: 1 article (05/2010)
10.	Markelova, Maria Rivera: 1 article (05/2010)

Related Diseases

1.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 05/01/2010 - "In agreement with this notion, CP-4200 showed a significantly higher antitumoral activity than azacytidine in an orthotopic mouse tumor model for acute lymphocytic leukemia. "
2.	Neoplasms (Cancer) 05/01/2010 - "In agreement with this notion, CP-4200 showed a significantly higher antitumoral activity than azacytidine in an orthotopic mouse tumor model for acute lymphocytic leukemia. " 05/01/2010 - "We show here that CP-4200, an elaidic acid derivative of azacytidine, has strong epigenetic modulatory potency in human cancer cell lines, as evidenced by efficient depletion of DNA methyltransferase protein, genome-wide DNA demethylation, and robust reactivation of epigenetically silenced tumor suppressor genes. "
3.	Leukemia 09/01/2013 - "The role of human equilibrative nucleoside transporter 1 on the cellular transport of the DNA methyltransferase inhibitors 5-azacytidine and CP-4200 in human leukemia cells."

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Azacitidine (5 Azacytidine)
3.	Equilibrative Nucleoside Transporter 1
4.	Protein Methyltransferases
5.	Methyltransferases
6.	elaidic acid