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SGA 360

an Ah receptor modulator with anti-inflammatory activity; structure in first source

Also Known As:

SGA-360; SGA360

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkenes: 265
      - Allyl Compounds: 7
        SGA 360: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - Indazoles: 179
        SGA 360: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indazoles: 179
      - SGA 360: 2

Experts

1.	Murray, Iain A: 2 articles (12/2017 - 05/2010)
2.	Perdew, Gary H: 2 articles (12/2017 - 05/2010)
3.	Amin, Shantu G: 1 article (12/2017)
4.	Gowda, Krishne: 1 article (12/2017)
5.	Hubbard, Troy D: 1 article (12/2017)
6.	Kuzu, Guray: 1 article (12/2017)
7.	Lahoti, Tejas S: 1 article (12/2017)
8.	Muku, Gulsum E: 1 article (12/2017)
9.	Podolsky, Michael A: 1 article (12/2017)
10.	Smith, Kayla J: 1 article (12/2017)

Related Diseases

1.	Edema (Dropsy) 05/17/2010 - "SGA 360 was tested in a 12-O-tetradecanoylphorbol-13-acetate (TPA)-mediated ear inflammatory edema model using C57BL6/J and Ahr(-/-) mice. " 12/01/2017 - "Topical exposure to SGA360 was also able to mitigate joint edema in a monosodium urate (MSU) crystal gout mouse model. "
2.	Shock 12/01/2017 - "Exposure to SGA360 was capable of significantly inhibiting lipopolysaccharide (LPS)-mediated endotoxic shock in a mouse model, both in terms of lethality and attenuating inflammatory signaling in tissues. "
3.	Inflammation (Inflammations) 12/01/2017 - "In vivo macrophage-driven acute inflammation models were utilized here to test whether the selective Ah receptor modulator 1-allyl-7-trifluoromethyl-1H-indazol-3-yl]-4-methoxyphenol (SGA360) would reduce inflammation. "
4.	Gout 12/01/2017 - "Topical exposure to SGA360 was also able to mitigate joint edema in a monosodium urate (MSU) crystal gout mouse model. "

Related Drugs and Biologics

1.	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
2.	Uric Acid (Urate)
3.	Lipopolysaccharides