HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

BPR1P0034

has potent and selective anti-influenza virus activity; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - BPR1P0034: 1

Experts

1.	Chao, Yu-Sheng: 1 article (02/2010)
2.	Chen, Hsiun-Ling: 1 article (02/2010)
3.	Chu, Tzu-Yun: 1 article (02/2010)
4.	Horng, Jim-Tong: 1 article (02/2010)
5.	Hsieh, Hsing-Pang: 1 article (02/2010)
6.	Hsu, John Ta: 1 article (02/2010)
7.	Reddy, Gadarla Randheer: 1 article (02/2010)
8.	Shih, Shin-Ru: 1 article (02/2010)
9.	Tang, Wen-Fang: 1 article (02/2010)
10.	Tseng, Sung-Nain: 1 article (02/2010)

Related Diseases

1.	Virus Diseases (Viral Diseases) 02/23/2010 - "BPR1P0034 exhibited broad inhibition spectrum for influenza viruses but showed no antiviral effect for enteroviruses and echovirus 9. In a time-of-addition assay, in which the compound was added at different stages along the viral replication cycle (such as at adsorption or after adsorption), its antiviral activity was more efficient in cells treated with the test compound between 0 and 2 h, right after viral infection, implying that an early step of viral replication might be the target of the compound. "
2.	Human Influenza (Influenza) 02/23/2010 - "To the best of our knowledge, BPR1P0034 is the first pyrazole-based anti-influenza compound ever identified and characterized from high throughput screening to show potent (sub-microM) antiviral activity. "

Related Drugs and Biologics

1.	Antiviral Agents (Antivirals)
2.	pyrazole