selenoneine

isolated from the blood of bluefin tuna, Thunnus orientalis; structure in first source

Also Known As:

2-selenyl-Nalpha,Nalpha,Nalpha-trimethylhistidine; 3-(2-hydroselno-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate

Networked: 5 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Histidine: 2980
      - selenoneine: 5
  - Cyclic Amino Acids: 3
    - Histidine: 2980
      - selenoneine: 5
Organic Chemicals: 133
- Organoselenium Compounds: 63
  - selenoneine: 5

Experts

1.	Yamashita, Michiaki: 3 articles (06/2020 - 05/2010)
2.	Yamashita, Yumiko: 2 articles (01/2018 - 05/2010)
3.	Matsushita, Koki: 1 article (06/2020)
4.	Miyata, Masaaki: 1 article (06/2020)
5.	Shimokawa, Yutaro: 1 article (06/2020)
6.	Shindo, Ryunosuke: 1 article (06/2020)
7.	Sugiura, Yoshimasa: 1 article (06/2020)
8.	Masuda, Junko: 1 article (01/2018)
9.	Seko, Takuya: 1 article (01/2018)
10.	Umemura, Chiho: 1 article (01/2018)

Related Diseases

1.	Non-alcoholic Fatty Liver Disease 06/26/2020 - "Selenoneine Ameliorates Hepatocellular Injury and Hepatic Steatosis in a Mouse Model of NAFLD." 06/26/2020 - "This study aimed to determine whether selenoneine attenuates hepatocellular injury and hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD). " 06/26/2020 - "These results suggest that selenoneine attenuates hepatic steatosis and hepatocellular injury in an NAFLD mouse model."
2.	Carcinogenesis 01/01/2018 - "The aim of this study was to determine whether a selenoneine-rich diet exerts antioxidant activities that can prevent carcinogenesis in two types of colorectal cancer model in mice. " 01/01/2018 - "We administrated selenoneine-containing tuna dark muscle extract (STDME) to mice for one week and used azoxymethane (AOM) and dextran sodium sulfate (DSS) for inducing colorectal carcinogenesis. " 05/26/2010 - "Thus, the dietary intake of selenoneine, by consuming fish, might decrease the formation of reactive oxygen radicals that could oxidize nucleotides in DNA, and thereby inhibit carcinogenesis, chronic diseases, and aging."
3.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2018 - "Dietary Supplementation of Selenoneine-Containing Tuna Dark Muscle Extract Effectively Reduces Pathology of Experimental Colorectal Cancers in Mice." 01/01/2018 - "The aim of this study was to determine whether a selenoneine-rich diet exerts antioxidant activities that can prevent carcinogenesis in two types of colorectal cancer model in mice. "
4.	Chronic Disease (Chronic Diseases) 12/01/2023 - "Ergothioneine and selenoneine are structurally related dietary antioxidants and cytoprotectants that may help prevent several chronic diseases associated with inflammation and aging. " 05/26/2010 - "Thus, the dietary intake of selenoneine, by consuming fish, might decrease the formation of reactive oxygen radicals that could oxidize nucleotides in DNA, and thereby inhibit carcinogenesis, chronic diseases, and aging."
5.	Thrombosis (Thrombus) 06/26/2020 - "A marked accumulation of selenoneine was found in the liver and blood clot of the selenoneine group. " 06/26/2020 - "Hepatic and blood clot total selenium concentrations were 1.7 and 1.9 times higher in the selenoneine group than in the control group. "

Related Drugs and Biologics

1.	Antioxidants
2.	Sodium Selenite
3.	Reactive Oxygen Species (Oxygen Radicals)
4.	Triglycerides (Triacylglycerol)
5.	Selenomethionine (Sethotope)
6.	Selenium
7.	Nucleotides
8.	Ergothioneine
9.	DNA (Deoxyribonucleic Acid)
10.	Dextrans (Dextran)